SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wyy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_D_SAMD301_1 (PUTATIVE METHYLTRANSFERASE BUD23)	1wyy	E2 GLYCOPROTEIN (Severe acute respiratory syndrome-related coronavirus)	4 / 5	GLN A 947 LEU A 948 SER A 949 ASP A 961	None	1.26A	4qtuD-1wyyA: undetectable	4qtuD-1wyyA: 20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVY_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	1wyy	E2 GLYCOPROTEIN (Severe acute respiratory syndrome-related coronavirus)	5 / 11	THR A 921 THR A 922 THR A 923 SER A 914 ALA A1171	None	1.28A	4qvyV-1wyyA: undetectable 4qvyb-1wyyA: undetectable	4qvyV-1wyyA: 22.78 4qvyb-1wyyA: 24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVY_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	1wyy	E2 GLYCOPROTEIN (Severe acute respiratory syndrome-related coronavirus)	5 / 11	THR A 921 THR A 922 THR A 923 SER A 914 ALA A1171	None	1.28A	4qvyH-1wyyA: undetectable 4qvyN-1wyyA: undetectable	4qvyH-1wyyA: 22.78 4qvyN-1wyyA: 24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5F_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	1wyy	E2 GLYCOPROTEIN (Severe acute respiratory syndrome-related coronavirus)	5 / 11	THR A 921 THR A 922 THR A 923 SER A 914 ALA A1171	None	1.28A	5l5fV-1wyyA: undetectable 5l5fb-1wyyA: undetectable	5l5fV-1wyyA: 22.78 5l5fb-1wyyA: 24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5F_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	1wyy	E2 GLYCOPROTEIN (Severe acute respiratory syndrome-related coronavirus)	5 / 11	THR A 921 THR A 922 THR A 923 SER A 914 ALA A1171	None	1.28A	5l5fH-1wyyA: undetectable 5l5fN-1wyyA: undetectable	5l5fH-1wyyA: 22.78 5l5fN-1wyyA: 24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5Z_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	1wyy	E2 GLYCOPROTEIN (Severe acute respiratory syndrome-related coronavirus)	5 / 12	THR A 921 THR A 922 THR A 923 SER A 914 ALA A1171	None	1.28A	5l5zV-1wyyA: undetectable 5l5zb-1wyyA: undetectable	5l5zV-1wyyA: 22.78 5l5zb-1wyyA: 24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5Z_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	1wyy	E2 GLYCOPROTEIN (Severe acute respiratory syndrome-related coronavirus)	5 / 12	THR A 921 THR A 922 THR A 923 SER A 914 ALA A1171	None	1.28A	5l5zH-1wyyA: undetectable 5l5zN-1wyyA: undetectable	5l5zH-1wyyA: 22.78 5l5zN-1wyyA: 24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF3_B_BO2B305_1 (PROTEASOME SUBUNIT BETA TYPE-6)	1wyy	E2 GLYCOPROTEIN (Severe acute respiratory syndrome-related coronavirus)	5 / 12	THR A 921 THR A 922 THR A 923 SER A 914 ALA A1171	None	1.28A	5lf3b-1wyyA: undetectable	5lf3b-1wyyA: 22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF3_N_BO2N304_1 (PROTEASOME SUBUNIT BETA TYPE-6)	1wyy	E2 GLYCOPROTEIN (Severe acute respiratory syndrome-related coronavirus)	5 / 12	THR A 921 THR A 922 THR A 923 SER A 914 ALA A1171	None	1.28A	5lf3N-1wyyA: undetectable	5lf3N-1wyyA: 22.75

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4QTU_D_SAMD301_1","PUTATIVE METHYLTRANSFERASE BUD23","1wyy","E2 GLYCOPROTEIN","Severe acute respiratory syndrome-related coronavirus",4,"GLN A 947;LEU A 948;SER A 949;ASP A 961","None","1.26A","4qtuD-1wyyA:undetectable","4qtuD-1wyyA:20.90"],["4QVY_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","1wyy","E2 GLYCOPROTEIN","Severe acute respiratory syndrome-related coronavirus",5,"THR A 921;THR A 922;THR A 923;SER A 914;ALA A1171","None","1.28A","4qvyV-1wyyA:undetectable;4qvyb-1wyyA:undetectable","4qvyV-1wyyA:22.78;4qvyb-1wyyA:24.27"],["4QVY_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","1wyy","E2 GLYCOPROTEIN","Severe acute respiratory syndrome-related coronavirus",5,"THR A 921;THR A 922;THR A 923;SER A 914;ALA A1171","None","1.28A","4qvyH-1wyyA:undetectable;4qvyN-1wyyA:undetectable","4qvyH-1wyyA:22.78;4qvyN-1wyyA:24.27"],["5L5F_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","1wyy","E2 GLYCOPROTEIN","Severe acute respiratory syndrome-related coronavirus",5,"THR A 921;THR A 922;THR A 923;SER A 914;ALA A1171","None","1.28A","5l5fV-1wyyA:undetectable;5l5fb-1wyyA:undetectable","5l5fV-1wyyA:22.78;5l5fb-1wyyA:24.27"],["5L5F_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","1wyy","E2 GLYCOPROTEIN","Severe acute respiratory syndrome-related coronavirus",5,"THR A 921;THR A 922;THR A 923;SER A 914;ALA A1171","None","1.28A","5l5fH-1wyyA:undetectable;5l5fN-1wyyA:undetectable","5l5fH-1wyyA:22.78;5l5fN-1wyyA:24.27"],["5L5Z_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","1wyy","E2 GLYCOPROTEIN","Severe acute respiratory syndrome-related coronavirus",5,"THR A 921;THR A 922;THR A 923;SER A 914;ALA A1171","None","1.28A","5l5zV-1wyyA:undetectable;5l5zb-1wyyA:undetectable","5l5zV-1wyyA:22.78;5l5zb-1wyyA:24.27"],["5L5Z_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","1wyy","E2 GLYCOPROTEIN","Severe acute respiratory syndrome-related coronavirus",5,"THR A 921;THR A 922;THR A 923;SER A 914;ALA A1171","None","1.28A","5l5zH-1wyyA:undetectable;5l5zN-1wyyA:undetectable","5l5zH-1wyyA:22.78;5l5zN-1wyyA:24.27"],["5LF3_B_BO2B305_1","PROTEASOME SUBUNIT BETA TYPE-6","1wyy","E2 GLYCOPROTEIN","Severe acute respiratory syndrome-related coronavirus",5,"THR A 921;THR A 922;THR A 923;SER A 914;ALA A1171","None","1.28A","5lf3b-1wyyA:undetectable","5lf3b-1wyyA:22.75"],["5LF3_N_BO2N304_1","PROTEASOME SUBUNIT BETA TYPE-6","1wyy","E2 GLYCOPROTEIN","Severe acute respiratory syndrome-related coronavirus",5,"THR A 921;THR A 922;THR A 923;SER A 914;ALA A1171","None","1.28A","5lf3N-1wyyA:undetectable","5lf3N-1wyyA:22.75"]]