SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x0g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 1x0g ISCA
(Thermosynechococ
cus
elongatus) 		4 / 7 GLY A 104
THR A 100
MET A 105
SER A  35
 None
 1.25A 2o5yH-1x0gA:
undetectable
2o5yL-1x0gA:
undetectable		 2o5yH-1x0gA:
16.14
2o5yL-1x0gA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 1x0g ISCA
(Thermosynechococ
cus
elongatus) 		4 / 6 ILE A  27
ARG A  29
LEU A  56
ASP A  54
 None
 1.03A 2rlfA-1x0gA:
undetectable
2rlfD-1x0gA:
undetectable		 2rlfA-1x0gA:
17.17
2rlfD-1x0gA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 1x0g ISCA
(Thermosynechococ
cus
elongatus) 		4 / 6 ARG A  41
MET A 105
PHE A  92
PHE A  90
 FES  A 500 ( 4.9A)
None
None
None
 1.42A 3af3A-1x0gA:
undetectable		 3af3A-1x0gA:
20.46