SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x0u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FB7_A_ROCA100_1 (HIV-1 PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.84A	1fb7A-1x0uA: undetectable	1fb7A-1x0uA: 11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FO4_B_SALB4005_1 (XANTHINE DEHYDROGENASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 7	ARG A 513 THR A 399 VAL A 400 ALA A 394	None	0.93A	1fo4B-1x0uA: undetectable	1fo4B-1x0uA: 17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FOH_A_IPHA802_0 (PHENOL HYDROXYLASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 10	GLN A 99 VAL A 82 ILE A 116 TYR A 120 GLY A 132	None	1.20A	1fohA-1x0uA: undetectable	1fohA-1x0uA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FOH_B_IPHB802_0 (PHENOL HYDROXYLASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 10	GLN A 99 VAL A 82 ILE A 116 TYR A 120 GLY A 132	None	1.19A	1fohB-1x0uA: undetectable	1fohB-1x0uA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FOH_C_IPHC802_0 (PHENOL HYDROXYLASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 10	GLN A 99 VAL A 82 ILE A 116 TYR A 120 GLY A 132	None	1.21A	1fohC-1x0uA: undetectable	1fohC-1x0uA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_C_SAMC2293_0 (GLYCINE N-METHYLTRANSFERASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	TYR A 97 ALA A 43 GLY A 138 SER A 136 TYR A 151	None	1.15A	1nbiC-1x0uA: undetectable	1nbiC-1x0uA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_D_SAMD3293_0 (GLYCINE N-METHYLTRANSFERASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	TYR A 97 ALA A 43 GLY A 138 SER A 136 TYR A 151	None	1.15A	1nbiD-1x0uA: undetectable	1nbiD-1x0uA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AQU_B_DR7B300_1 (HIV-1 PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 10	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.79A	2aquA-1x0uA: undetectable	2aquA-1x0uA: 11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AQU_B_DR7B300_2 (HIV-1 PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 11	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.84A	2aquB-1x0uA: undetectable	2aquB-1x0uA: 11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVV_A_MK1A901_3 (POL POLYPROTEIN)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.79A	2avvB-1x0uA: undetectable	2avvB-1x0uA: 12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVV_E_MK1E902_2 (POL POLYPROTEIN)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	3 / 3	ASP A 426 ILE A 354 VAL A 368	None	0.28A	2avvD-1x0uA: undetectable	2avvD-1x0uA: 12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IJ7_C_TPFC2471_1 (CYTOCHROME P450 121)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 8	THR A 102 VAL A 103 VAL A 82 ALA A 23	None	0.92A	2ij7C-1x0uA: undetectable	2ij7C-1x0uA: 23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNP_A_ROCA401_1 (PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 11	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.92A	2nnpA-1x0uA: undetectable	2nnpA-1x0uA: 12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4K_A_DR7A301_2 (PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	6 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 403 ILE A 354 VAL A 368	None	1.23A	2o4kB-1x0uA: undetectable	2o4kB-1x0uA: 11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q5K_A_AB1A201_1 (PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 9	ALA A 347 ASP A 348 GLY A 383 ILE A 385 ILE A 342	None	0.92A	2q5kA-1x0uA: undetectable	2q5kA-1x0uA: 11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q5K_A_AB1A201_2 (PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 403 ILE A 354	None	0.87A	2q5kB-1x0uA: undetectable	2q5kB-1x0uA: 11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q63_A_1UNA1001_1 (PROTEASE RETROPEPSIN)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.83A	2q63A-1x0uA: undetectable	2q63A-1x0uA: 11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QX4_A_ML1A233_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 8	ILE A 141 PHE A 200 GLY A 138 GLY A 137	None	0.82A	2qx4A-1x0uA: 2.6 2qx4B-1x0uA: 2.3	2qx4A-1x0uA: 17.77 2qx4B-1x0uA: 17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2R5P_D_MK1D902_2 (PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	6 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 403 ILE A 354 VAL A 368	None	1.22A	2r5pD-1x0uA: undetectable	2r5pD-1x0uA: 17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VJ1_A_BEZA1303_0 (SARS CORONAVIRUS MAIN PROTEINASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	3 / 3	HIS A 226 MET A 191 MET A 199	None	1.34A	2vj1A-1x0uA: undetectable	2vj1A-1x0uA: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7K_A_SALA1303_1 (LYSR-TYPE REGULATORY PROTEIN)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 7	PRO A 375 ILE A 384 PRO A 371 GLY A 372	None	0.91A	2y7kA-1x0uA: undetectable	2y7kA-1x0uA: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZM_A_SAMA401_0 (UNCHARACTERIZED PROTEIN MJ0883)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	PHE A 338 PRO A 289 ILE A 342 ASN A 333 VAL A 374	None	1.06A	2zzmA-1x0uA: undetectable	2zzmA-1x0uA: 23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZN_A_SAMA401_0 (UNCHARACTERIZED PROTEIN MJ0883)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	PHE A 338 PRO A 289 ILE A 342 ASN A 333 VAL A 374	None	1.07A	2zznA-1x0uA: undetectable	2zznA-1x0uA: 23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOD_A_MIYA2001_1 (ACRIFLAVINE RESISTANCE PROTEIN B)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 8	GLY A 144 GLU A 69 ILE A 141 ALA A 139	None	0.80A	3aodA-1x0uA: undetectable	3aodA-1x0uA: 18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOD_A_MIYA2001_1 (ACRIFLAVINE RESISTANCE PROTEIN B)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 8	PHE A 338 GLY A 340 ILE A 342 ALA A 346	None	0.94A	3aodA-1x0uA: undetectable	3aodA-1x0uA: 18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ARR_A_PNXA607_1 (CHITINASE A)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 7	VAL A 368 SER A 410 HIS A 415 THR A 404	None	0.98A	3arrA-1x0uA: undetectable	3arrA-1x0uA: 22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AX7_B_SALB1336_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 9	ARG A 513 THR A 399 VAL A 400 LEU A 364 ALA A 394	None	1.12A	3ax7B-1x0uA: 0.0	3ax7B-1x0uA: 17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL1_A_DR7A100_2 (PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.89A	3el1B-1x0uA: undetectable	3el1B-1x0uA: 11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FAL_A_REAA501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 10	ILE A 316 ALA A 313 GLN A 314 ARG A 293 ILE A 354	None	1.05A	3falA-1x0uA: 0.5	3falA-1x0uA: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JW2_A_017A401_2 (GAG-POL POLYPROTEIN)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	6 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 403 ILE A 354 VAL A 368	None	1.32A	3jw2B-1x0uA: undetectable	3jw2B-1x0uA: 12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K4V_B_ROCB201_1 (HIV-1 PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.82A	3k4vA-1x0uA: undetectable	3k4vA-1x0uA: 12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LZV_A_017A200_1 (HIV-1 PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 10	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.85A	3lzvA-1x0uA: undetectable	3lzvA-1x0uA: 11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDT_A_ROCA101_1 (PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.83A	3ndtA-1x0uA: undetectable	3ndtA-1x0uA: 12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NXU_B_RITB600_2 (CYTOCHROME P450 3A4)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 9	ARG A 466 ILE A 453 ARG A 471 LEU A 473 GLY A 440	None	1.43A	3nxuB-1x0uA: undetectable	3nxuB-1x0uA: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OY4_B_017B200_2 (HIV-1 PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 10	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.81A	3oy4B-1x0uA: undetectable	3oy4B-1x0uA: 11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QOW_A_SAMA417_0 (HISTONE-LYSINE N-METHYLTRANSFERASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	GLY A 132 GLY A 85 VAL A 82 ALA A 123 PHE A 51	None	1.26A	3qowA-1x0uA: undetectable	3qowA-1x0uA: 23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SO9_A_017A100_1 (HIV-1 PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 8	GLY A 424 ALA A 425 ASP A 426 ILE A 354	None	0.63A	3so9A-1x0uA: undetectable	3so9A-1x0uA: 10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3C_A_017A201_1 (HIV-1 PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 7	GLY A 424 ALA A 425 ASP A 426 ILE A 354	None	0.47A	3t3cA-1x0uA: undetectable	3t3cA-1x0uA: 11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_C_ROCC901_3 (PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	3 / 3	ASP A 345 THR A 370 PRO A 371	None	0.67A	3tkgD-1x0uA: undetectable	3tkgD-1x0uA: 13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TL9_A_ROCA401_1 (PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.81A	3tl9A-1x0uA: undetectable	3tl9A-1x0uA: 13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TTP_A_017A201_1 (HIV-1 PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	6 / 10	ALA A 347 ASP A 348 ASP A 345 GLY A 383 ILE A 385 ILE A 342	None	1.27A	3ttpA-1x0uA: undetectable	3ttpA-1x0uA: 12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UQB_A_FK5A114_1 (UBIQUITIN-LIKE PROTEIN SMT3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 8	PHE A 395 VAL A 331 ILE A 330 ILE A 499	None	0.83A	3uqbA-1x0uA: undetectable	3uqbA-1x0uA: 16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W1W_B_CHDB504_0 (FERROCHELATASE, MITOCHONDRIAL)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	LEU A 246 LEU A 306 ILE A 192 VAL A 318 VAL A 233	None	1.42A	3w1wB-1x0uA: undetectable	3w1wB-1x0uA: 19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BLV_B_SAMB1281_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	LYS A 40 ASP A 100 GLY A 105 LEU A 108 ASP A 135	None	1.15A	4blvB-1x0uA: undetectable	4blvB-1x0uA: 21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DQF_B_017B101_2 (ASPARTYL PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 10	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.85A	4dqfB-1x0uA: undetectable	4dqfB-1x0uA: 17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J4V_E_SVRE301_1 (NUCLEOCAPSID PROTEIN)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 10	GLY A 329 ARG A 352 ALA A 351 VAL A 331 PHE A 305	None	1.49A	4j4vA-1x0uA: 0.5 4j4vE-1x0uA: 0.8	4j4vA-1x0uA: 20.87 4j4vE-1x0uA: 20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J5J_B_478B401_2 (PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 10	ALA A 332 ILE A 295 VAL A 407 ILE A 403 VAL A 300	None	1.01A	4j5jB-1x0uA: undetectable	4j5jB-1x0uA: 16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JEC_B_478B401_1 (HIV-1 PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.80A	4jecA-1x0uA: undetectable	4jecA-1x0uA: 12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKV_B_AERB601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	ALA A 394 ILE A 342 ILE A 316 VAL A 331 VAL A 318	None	0.90A	4nkvB-1x0uA: undetectable	4nkvB-1x0uA: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_A_STRA601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	ALA A 394 ILE A 342 ILE A 316 VAL A 331 VAL A 318	None	0.88A	4nkxA-1x0uA: undetectable	4nkxA-1x0uA: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q1W_A_017A104_1 (ASPARTYL PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 9	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.82A	4q1wA-1x0uA: undetectable	4q1wA-1x0uA: 11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q1X_A_017A101_1 (ASPARTYL PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 11	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.82A	4q1xA-1x0uA: undetectable	4q1xA-1x0uA: 16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q1Y_A_017A106_1 (ASPARTYL PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 10	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.79A	4q1yA-1x0uA: undetectable	4q1yA-1x0uA: 16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QGI_A_ROCA101_1 (PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 11	GLY A 424 ALA A 425 ASP A 426 ILE A 354 VAL A 368	None	0.91A	4qgiA-1x0uA: undetectable	4qgiA-1x0uA: 11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_B_BQ1B1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 8	ALA A 359 GLU A 397 ALA A 396 PHE A 395 LEU A 364	None	1.33A	4v1fA-1x0uA: undetectable 4v1fB-1x0uA: undetectable	4v1fA-1x0uA: 11.78 4v1fB-1x0uA: 11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_B_BQ1B1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 8	ALA A 359 GLU A 397 ALA A 396 PHE A 395 LEU A 364	None	1.37A	4v1fA-1x0uA: undetectable 4v1fB-1x0uA: undetectable	4v1fA-1x0uA: 11.78 4v1fB-1x0uA: 11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XDT_A_ACTA407_0 (FAD:PROTEIN FMN TRANSFERASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	3 / 3	ASP A 266 GLY A 268 ASP A 269	None	0.64A	4xdtA-1x0uA: 0.5	4xdtA-1x0uA: 22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CU6_A_ACTA403_0 (CASEIN KINASE II SUBUNIT ALPHA)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 6	TYR A 478 ILE A 406 VAL A 489 ALA A 430	None	0.83A	5cu6A-1x0uA: undetectable	5cu6A-1x0uA: 19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_B_PAUB601_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 7	GLU A 143 GLY A 81 SER A 107 GLY A 105	None	0.86A	5e26A-1x0uA: undetectable 5e26B-1x0uA: undetectable	5e26A-1x0uA: 21.55 5e26B-1x0uA: 21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IMS_A_ACTA708_0 (ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	3 / 3	GLY A 138 GLY A 137 GLN A 99	None	0.44A	5imsA-1x0uA: 2.4	5imsA-1x0uA: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KPR_A_PAUA404_0 (PANTOTHENATE KINASE 3)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 5	GLU A 143 GLY A 81 SER A 107 GLY A 105	None	0.93A	5kprA-1x0uA: undetectable	5kprA-1x0uA: 20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KQY_B_017B101_2 (PROTEASE E35D-DRV)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 7	GLY A 424 ALA A 425 ASP A 426 ILE A 354	None	0.50A	5kqyB-1x0uA: undetectable	5kqyB-1x0uA: 12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KR1_B_017B101_2 (PROTEASE PR5-DRV)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 8	GLY A 424 ALA A 425 ASP A 426 ILE A 354	None	0.52A	5kr1B-1x0uA: undetectable	5kr1B-1x0uA: 17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UL4_A_SAMA803_0 (OXSB PROTEIN)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 12	PHE A 353 GLY A 329 GLY A 319 ILE A 296 MET A 292	None	1.16A	5ul4A-1x0uA: 2.9	5ul4A-1x0uA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZBD_B_TRPB501_0 (FLAVIN-DEPENDENT L-TRYPTOPHAN OXIDASE VIOA)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 10	ARG A 140 ALA A 43 HIS A 112 ASP A 100 GLY A 137	None	1.31A	5zbdB-1x0uA: 0.1	5zbdB-1x0uA: 21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJ1_B_AB1B201_1 (HIV-1 PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	6 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 403 ILE A 354 VAL A 368	None	1.17A	6dj1B-1x0uA: undetectable	6dj1B-1x0uA: 9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJ2_B_AB1B201_0 (HIV-1 PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	5 / 10	ALA A 347 ASP A 348 GLY A 383 ILE A 385 ILE A 342	None	0.93A	6dj2A-1x0uA: undetectable	6dj2A-1x0uA: 15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJ2_B_AB1B201_1 (HIV-1 PROTEASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	6 / 12	GLY A 424 ALA A 425 ASP A 426 ILE A 403 ILE A 354 VAL A 368	None	1.16A	6dj2B-1x0uA: undetectable	6dj2B-1x0uA: 15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EKZ_A_SNPA413_0 (AROMATIC PEROXYGENASE)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 7	GLY A 81 SER A 136 GLY A 106 VAL A 103	None	0.92A	6ekzA-1x0uA: undetectable	6ekzA-1x0uA: 11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD6_B_STIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	1x0u	HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT (Sulfurisphaera tokodaii)	4 / 7	VAL A 131 ILE A 116 GLY A 27 ALA A 43	None	0.90A	6hd6B-1x0uA: undetectable	6hd6B-1x0uA: 10.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FB7_A_ROCA100_1","HIV-1 PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.84A","1fb7A-1x0uA:undetectable","1fb7A-1x0uA:11.65"],["1FO4_B_SALB4005_1","XANTHINE DEHYDROGENASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"ARG A 513;THR A 399;VAL A 400;ALA A 394","None","0.93A","1fo4B-1x0uA:undetectable","1fo4B-1x0uA:17.47"],["1FOH_A_IPHA802_0","PHENOL HYDROXYLASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLN A  99;VAL A  82;ILE A 116;TYR A 120;GLY A 132","None","1.20A","1fohA-1x0uA:undetectable","1fohA-1x0uA:22.13"],["1FOH_B_IPHB802_0","PHENOL HYDROXYLASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLN A  99;VAL A  82;ILE A 116;TYR A 120;GLY A 132","None","1.19A","1fohB-1x0uA:undetectable","1fohB-1x0uA:22.13"],["1FOH_C_IPHC802_0","PHENOL HYDROXYLASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLN A  99;VAL A  82;ILE A 116;TYR A 120;GLY A 132","None","1.21A","1fohC-1x0uA:undetectable","1fohC-1x0uA:22.13"],["1NBI_C_SAMC2293_0","GLYCINE N-METHYLTRANSFERASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"TYR A  97;ALA A  43;GLY A 138;SER A 136;TYR A 151","None","1.15A","1nbiC-1x0uA:undetectable","1nbiC-1x0uA:21.43"],["1NBI_D_SAMD3293_0","GLYCINE N-METHYLTRANSFERASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"TYR A  97;ALA A  43;GLY A 138;SER A 136;TYR A 151","None","1.15A","1nbiD-1x0uA:undetectable","1nbiD-1x0uA:21.43"],["2AQU_B_DR7B300_1","HIV-1 PROTEASE;HIV-1 PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.79A","2aquA-1x0uA:undetectable","2aquA-1x0uA:11.67"],["2AQU_B_DR7B300_2","HIV-1 PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.84A","2aquB-1x0uA:undetectable","2aquB-1x0uA:11.67"],["2AVV_A_MK1A901_3","POL POLYPROTEIN;POL POLYPROTEIN","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.79A","2avvB-1x0uA:undetectable","2avvB-1x0uA:12.26"],["2AVV_E_MK1E902_2","POL POLYPROTEIN;POL POLYPROTEIN","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",3,"ASP A 426;ILE A 354;VAL A 368","None","0.28A","2avvD-1x0uA:undetectable","2avvD-1x0uA:12.26"],["2IJ7_C_TPFC2471_1","CYTOCHROME P450 121","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"THR A 102;VAL A 103;VAL A  82;ALA A  23","None","0.92A","2ij7C-1x0uA:undetectable","2ij7C-1x0uA:23.16"],["2NNP_A_ROCA401_1","PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.92A","2nnpA-1x0uA:undetectable","2nnpA-1x0uA:12.07"],["2O4K_A_DR7A301_2","PROTEASE;PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",6,"GLY A 424;ALA A 425;ASP A 426;ILE A 403;ILE A 354;VAL A 368","None","1.23A","2o4kB-1x0uA:undetectable","2o4kB-1x0uA:11.65"],["2Q5K_A_AB1A201_1","PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"ALA A 347;ASP A 348;GLY A 383;ILE A 385;ILE A 342","None","0.92A","2q5kA-1x0uA:undetectable","2q5kA-1x0uA:11.84"],["2Q5K_A_AB1A201_2","PROTEASE;PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 403;ILE A 354","None","0.87A","2q5kB-1x0uA:undetectable","2q5kB-1x0uA:11.84"],["2Q63_A_1UNA1001_1","PROTEASE RETROPEPSIN","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.83A","2q63A-1x0uA:undetectable","2q63A-1x0uA:11.48"],["2QX4_A_ML1A233_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"ILE A 141;PHE A 200;GLY A 138;GLY A 137","None","0.82A","2qx4A-1x0uA:2.6;2qx4B-1x0uA:2.3","2qx4A-1x0uA:17.77;2qx4B-1x0uA:17.77"],["2R5P_D_MK1D902_2","PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",6,"GLY A 424;ALA A 425;ASP A 426;ILE A 403;ILE A 354;VAL A 368","None","1.22A","2r5pD-1x0uA:undetectable","2r5pD-1x0uA:17.98"],["2VJ1_A_BEZA1303_0","SARS CORONAVIRUS MAIN PROTEINASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",3,"HIS A 226;MET A 191;MET A 199","None","1.34A","2vj1A-1x0uA:undetectable","2vj1A-1x0uA:20.61"],["2Y7K_A_SALA1303_1","LYSR-TYPE REGULATORY PROTEIN","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"PRO A 375;ILE A 384;PRO A 371;GLY A 372","None","0.91A","2y7kA-1x0uA:undetectable","2y7kA-1x0uA:16.31"],["2ZZM_A_SAMA401_0","UNCHARACTERIZED PROTEIN MJ0883","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"PHE A 338;PRO A 289;ILE A 342;ASN A 333;VAL A 374","None","1.06A","2zzmA-1x0uA:undetectable","2zzmA-1x0uA:23.42"],["2ZZN_A_SAMA401_0","UNCHARACTERIZED PROTEIN MJ0883","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"PHE A 338;PRO A 289;ILE A 342;ASN A 333;VAL A 374","None","1.07A","2zznA-1x0uA:undetectable","2zznA-1x0uA:23.42"],["3AOD_A_MIYA2001_1","ACRIFLAVINE RESISTANCE PROTEIN B","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"GLY A 144;GLU A  69;ILE A 141;ALA A 139","None","0.80A","3aodA-1x0uA:undetectable","3aodA-1x0uA:18.74"],["3AOD_A_MIYA2001_1","ACRIFLAVINE RESISTANCE PROTEIN B","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"PHE A 338;GLY A 340;ILE A 342;ALA A 346","None","0.94A","3aodA-1x0uA:undetectable","3aodA-1x0uA:18.74"],["3ARR_A_PNXA607_1","CHITINASE A","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"VAL A 368;SER A 410;HIS A 415;THR A 404","None","0.98A","3arrA-1x0uA:undetectable","3arrA-1x0uA:22.49"],["3AX7_B_SALB1336_1","XANTHINE DEHYDROGENASE\/OXIDASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"ARG A 513;THR A 399;VAL A 400;LEU A 364;ALA A 394","None","1.12A","3ax7B-1x0uA:0.0","3ax7B-1x0uA:17.47"],["3EL1_A_DR7A100_2","PROTEASE;PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.89A","3el1B-1x0uA:undetectable","3el1B-1x0uA:11.65"],["3FAL_A_REAA501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"ILE A 316;ALA A 313;GLN A 314;ARG A 293;ILE A 354","None","1.05A","3falA-1x0uA:0.5","3falA-1x0uA:19.85"],["3JW2_A_017A401_2","GAG-POL POLYPROTEIN;GAG-POL POLYPROTEIN","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",6,"GLY A 424;ALA A 425;ASP A 426;ILE A 403;ILE A 354;VAL A 368","None","1.32A","3jw2B-1x0uA:undetectable","3jw2B-1x0uA:12.26"],["3K4V_B_ROCB201_1","HIV-1 PROTEASE;HIV-1 PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.82A","3k4vA-1x0uA:undetectable","3k4vA-1x0uA:12.07"],["3LZV_A_017A200_1","HIV-1 PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.85A","3lzvA-1x0uA:undetectable","3lzvA-1x0uA:11.65"],["3NDT_A_ROCA101_1","PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.83A","3ndtA-1x0uA:undetectable","3ndtA-1x0uA:12.07"],["3NXU_B_RITB600_2","CYTOCHROME P450 3A4","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"ARG A 466;ILE A 453;ARG A 471;LEU A 473;GLY A 440","None","1.43A","3nxuB-1x0uA:undetectable","3nxuB-1x0uA:21.39"],["3OY4_B_017B200_2","HIV-1 PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.81A","3oy4B-1x0uA:undetectable","3oy4B-1x0uA:11.46"],["3QOW_A_SAMA417_0","HISTONE-LYSINE N-METHYLTRANSFERASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 132;GLY A  85;VAL A  82;ALA A 123;PHE A  51","None","1.26A","3qowA-1x0uA:undetectable","3qowA-1x0uA:23.40"],["3SO9_A_017A100_1","HIV-1 PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"GLY A 424;ALA A 425;ASP A 426;ILE A 354","None","0.63A","3so9A-1x0uA:undetectable","3so9A-1x0uA:10.73"],["3T3C_A_017A201_1","HIV-1 PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"GLY A 424;ALA A 425;ASP A 426;ILE A 354","None","0.47A","3t3cA-1x0uA:undetectable","3t3cA-1x0uA:11.84"],["3TKG_C_ROCC901_3","PROTEASE;PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",3,"ASP A 345;THR A 370;PRO A 371","None","0.67A","3tkgD-1x0uA:undetectable","3tkgD-1x0uA:13.61"],["3TL9_A_ROCA401_1","PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.81A","3tl9A-1x0uA:undetectable","3tl9A-1x0uA:13.61"],["3TTP_A_017A201_1","HIV-1 PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",6,"ALA A 347;ASP A 348;ASP A 345;GLY A 383;ILE A 385;ILE A 342","None","1.27A","3ttpA-1x0uA:undetectable","3ttpA-1x0uA:12.04"],["3UQB_A_FK5A114_1","UBIQUITIN-LIKE PROTEIN SMT3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"PHE A 395;VAL A 331;ILE A 330;ILE A 499","None","0.83A","3uqbA-1x0uA:undetectable","3uqbA-1x0uA:16.45"],["3W1W_B_CHDB504_0","FERROCHELATASE, MITOCHONDRIAL","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"LEU A 246;LEU A 306;ILE A 192;VAL A 318;VAL A 233","None","1.42A","3w1wB-1x0uA:undetectable","3w1wB-1x0uA:19.77"],["4BLV_B_SAMB1281_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"LYS A  40;ASP A 100;GLY A 105;LEU A 108;ASP A 135","None","1.15A","4blvB-1x0uA:undetectable","4blvB-1x0uA:21.40"],["4DQF_B_017B101_2","ASPARTYL PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.85A","4dqfB-1x0uA:undetectable","4dqfB-1x0uA:17.42"],["4J4V_E_SVRE301_1","NUCLEOCAPSID PROTEIN;NUCLEOCAPSID PROTEIN","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 329;ARG A 352;ALA A 351;VAL A 331;PHE A 305","None","1.49A","4j4vA-1x0uA:0.5;4j4vE-1x0uA:0.8","4j4vA-1x0uA:20.87;4j4vE-1x0uA:20.87"],["4J5J_B_478B401_2","PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"ALA A 332;ILE A 295;VAL A 407;ILE A 403;VAL A 300","None","1.01A","4j5jB-1x0uA:undetectable","4j5jB-1x0uA:16.29"],["4JEC_B_478B401_1","HIV-1 PROTEASE;HIV-1 PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.80A","4jecA-1x0uA:undetectable","4jecA-1x0uA:12.26"],["4NKV_B_AERB601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"ALA A 394;ILE A 342;ILE A 316;VAL A 331;VAL A 318","None","0.90A","4nkvB-1x0uA:undetectable","4nkvB-1x0uA:21.12"],["4NKX_A_STRA601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"ALA A 394;ILE A 342;ILE A 316;VAL A 331;VAL A 318","None","0.88A","4nkxA-1x0uA:undetectable","4nkxA-1x0uA:21.12"],["4Q1W_A_017A104_1","ASPARTYL PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.82A","4q1wA-1x0uA:undetectable","4q1wA-1x0uA:11.46"],["4Q1X_A_017A101_1","ASPARTYL PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.82A","4q1xA-1x0uA:undetectable","4q1xA-1x0uA:16.85"],["4Q1Y_A_017A106_1","ASPARTYL PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.79A","4q1yA-1x0uA:undetectable","4q1yA-1x0uA:16.85"],["4QGI_A_ROCA101_1","PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"GLY A 424;ALA A 425;ASP A 426;ILE A 354;VAL A 368","None","0.91A","4qgiA-1x0uA:undetectable","4qgiA-1x0uA:11.48"],["4V1F_B_BQ1B1087_0","F0F1 ATP SYNTHASE SUBUNIT C","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"ALA A 359;GLU A 397;ALA A 396;PHE A 395;LEU A 364","None","1.33A","4v1fA-1x0uA:undetectable;4v1fB-1x0uA:undetectable","4v1fA-1x0uA:11.78;4v1fB-1x0uA:11.78"],["4V1F_B_BQ1B1087_0","F0F1 ATP SYNTHASE SUBUNIT C","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"ALA A 359;GLU A 397;ALA A 396;PHE A 395;LEU A 364","None","1.37A","4v1fA-1x0uA:undetectable;4v1fB-1x0uA:undetectable","4v1fA-1x0uA:11.78;4v1fB-1x0uA:11.78"],["4XDT_A_ACTA407_0","FAD:PROTEIN FMN TRANSFERASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",3,"ASP A 266;GLY A 268;ASP A 269","None","0.64A","4xdtA-1x0uA:0.5","4xdtA-1x0uA:22.44"],["5CU6_A_ACTA403_0","CASEIN KINASE II SUBUNIT ALPHA","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"TYR A 478;ILE A 406;VAL A 489;ALA A 430","None","0.83A","5cu6A-1x0uA:undetectable","5cu6A-1x0uA:19.63"],["5E26_B_PAUB601_0","PANTOTHENATE KINASE 2, MITOCHONDRIAL","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"GLU A 143;GLY A  81;SER A 107;GLY A 105","None","0.86A","5e26A-1x0uA:undetectable;5e26B-1x0uA:undetectable","5e26A-1x0uA:21.55;5e26B-1x0uA:21.55"],["5IMS_A_ACTA708_0","ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",3,"GLY A 138;GLY A 137;GLN A  99","None","0.44A","5imsA-1x0uA:2.4","5imsA-1x0uA:23.44"],["5KPR_A_PAUA404_0","PANTOTHENATE KINASE 3","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"GLU A 143;GLY A  81;SER A 107;GLY A 105","None","0.93A","5kprA-1x0uA:undetectable","5kprA-1x0uA:20.11"],["5KQY_B_017B101_2","PROTEASE E35D-DRV","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"GLY A 424;ALA A 425;ASP A 426;ILE A 354","None","0.50A","5kqyB-1x0uA:undetectable","5kqyB-1x0uA:12.26"],["5KR1_B_017B101_2","PROTEASE PR5-DRV","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"GLY A 424;ALA A 425;ASP A 426;ILE A 354","None","0.52A","5kr1B-1x0uA:undetectable","5kr1B-1x0uA:17.42"],["5UL4_A_SAMA803_0","OXSB PROTEIN","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"PHE A 353;GLY A 329;GLY A 319;ILE A 296;MET A 292","None","1.16A","5ul4A-1x0uA:2.9","5ul4A-1x0uA:21.69"],["5ZBD_B_TRPB501_0","FLAVIN-DEPENDENT L-TRYPTOPHAN OXIDASE VIOA","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"ARG A 140;ALA A  43;HIS A 112;ASP A 100;GLY A 137","None","1.31A","5zbdB-1x0uA:0.1","5zbdB-1x0uA:21.07"],["6DJ1_B_AB1B201_1","HIV-1 PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",6,"GLY A 424;ALA A 425;ASP A 426;ILE A 403;ILE A 354;VAL A 368","None","1.17A","6dj1B-1x0uA:undetectable","6dj1B-1x0uA:9.86"],["6DJ2_B_AB1B201_0","HIV-1 PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",5,"ALA A 347;ASP A 348;GLY A 383;ILE A 385;ILE A 342","None","0.93A","6dj2A-1x0uA:undetectable","6dj2A-1x0uA:15.08"],["6DJ2_B_AB1B201_1","HIV-1 PROTEASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",6,"GLY A 424;ALA A 425;ASP A 426;ILE A 403;ILE A 354;VAL A 368","None","1.16A","6dj2B-1x0uA:undetectable","6dj2B-1x0uA:15.08"],["6EKZ_A_SNPA413_0","AROMATIC PEROXYGENASE","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"GLY A  81;SER A 136;GLY A 106;VAL A 103","None","0.92A","6ekzA-1x0uA:undetectable","6ekzA-1x0uA:11.19"],["6HD6_B_STIB601_1","TYROSINE-PROTEIN KINASE ABL1","1x0u","HYPOTHETICAL METHYLMALONYL-COA DECARBOXYLASE ALPHA SUBUNIT","Sulfurisphaera tokodaii",4,"VAL A 131;ILE A 116;GLY A  27;ALA A  43","None","0.90A","6hd6B-1x0uA:undetectable","6hd6B-1x0uA:10.11"]]