SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x3o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1x3o ACYL CARRIER PROTEIN
(Thermus
thermophilus) 		3 / 3 ASP A  16
ASP A  51
ASP A  41
 None
 0.70A 2igtA-1x3oA:
undetectable		 2igtA-1x3oA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1x3o ACYL CARRIER PROTEIN
(Thermus
thermophilus) 		3 / 3 ASP A  16
ASP A  51
ASP A  41
 None
 0.72A 2igtB-1x3oA:
undetectable		 2igtB-1x3oA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 1x3o ACYL CARRIER PROTEIN
(Thermus
thermophilus) 		4 / 7 VAL A  13
LEU A  45
PHE A  53
LEU A  55
 None
 0.96A 3qeoB-1x3oA:
undetectable		 3qeoB-1x3oA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TF1_A_ACTA191_0
(METHYL-ACCEPTING
CHEMOTAXIS PROTEIN)		 1x3o ACYL CARRIER PROTEIN
(Thermus
thermophilus) 		4 / 5 LYS A   1
ILE A   6
PHE A  53
LEU A  79
 None
 1.22A 3tf1A-1x3oA:
2.6		 3tf1A-1x3oA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1x3o ACYL CARRIER PROTEIN
(Thermus
thermophilus) 		4 / 6 LYS A  76
ILE A   6
VAL A  10
LEU A  49
 None
 1.03A 4em2A-1x3oA:
undetectable		 4em2A-1x3oA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 1x3o ACYL CARRIER PROTEIN
(Thermus
thermophilus) 		5 / 11 GLY A  48
LEU A  49
GLU A  52
ALA A  15
PHE A  53
 None
 0.89A 4wnuA-1x3oA:
undetectable		 4wnuA-1x3oA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 1x3o ACYL CARRIER PROTEIN
(Thermus
thermophilus) 		5 / 11 GLY A  48
LEU A  49
GLU A  52
ALA A  15
PHE A  53
 None
 1.08A 4wnuC-1x3oA:
undetectable		 4wnuC-1x3oA:
12.06