SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x42'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 GLU A  19
HIS A  95
HIS A  23
 None
 0.47A 1oe2A-1x42A:
undetectable		 1oe2A-1x42A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.56A 1v54A-1x42A:
undetectable		 1v54A-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.57A 1v54N-1x42A:
undetectable		 1v54N-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.56A 1v55A-1x42A:
undetectable		 1v55A-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.55A 1v55N-1x42A:
undetectable		 1v55N-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.55A 2dyrA-1x42A:
undetectable		 2dyrA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.58A 2dyrN-1x42A:
undetectable		 2dyrN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.58A 2dysA-1x42A:
0.2		 2dysA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.55A 2dysN-1x42A:
undetectable		 2dysN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.54A 2eijA-1x42A:
undetectable		 2eijA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.55A 2eijN-1x42A:
undetectable		 2eijN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.52A 2eikA-1x42A:
undetectable		 2eikA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.56A 2eikN-1x42A:
undetectable		 2eikN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.55A 2eilA-1x42A:
undetectable		 2eilA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.57A 2eilN-1x42A:
undetectable		 2eilN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.55A 2eimA-1x42A:
undetectable		 2eimA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.54A 2eimN-1x42A:
0.0		 2eimN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.57A 2einA-1x42A:
undetectable		 2einA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.67A 2einN-1x42A:
0.0		 2einN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		4 / 7 THR A 195
ASP A 213
VAL A 216
LEU A 112
 None
 1.02A 2hdnE-1x42A:
undetectable
2hdnF-1x42A:
undetectable
2hdnH-1x42A:
undetectable		 2hdnE-1x42A:
11.17
2hdnF-1x42A:
21.39
2hdnH-1x42A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		4 / 7 VAL A 216
LEU A 112
THR A 195
ASP A 213
 None
 1.03A 2hdnF-1x42A:
undetectable
2hdnG-1x42A:
undetectable
2hdnH-1x42A:
undetectable		 2hdnF-1x42A:
21.39
2hdnG-1x42A:
11.17
2hdnH-1x42A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.61A 2y69A-1x42A:
undetectable		 2y69A-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.62A 2y69N-1x42A:
undetectable		 2y69N-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.63A 2zxwA-1x42A:
undetectable		 2zxwA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.59A 2zxwN-1x42A:
undetectable		 2zxwN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.60A 3abkA-1x42A:
undetectable		 3abkA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.61A 3abkN-1x42A:
undetectable		 3abkN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.64A 3ablA-1x42A:
undetectable		 3ablA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.63A 3ablN-1x42A:
undetectable		 3ablN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.60A 3abmA-1x42A:
undetectable		 3abmA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.59A 3abmN-1x42A:
undetectable		 3abmN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.55A 3ag1A-1x42A:
undetectable		 3ag1A-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.58A 3ag1N-1x42A:
undetectable		 3ag1N-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.64A 3ag2A-1x42A:
undetectable		 3ag2A-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.62A 3ag2N-1x42A:
undetectable		 3ag2N-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.59A 3ag3A-1x42A:
undetectable		 3ag3A-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.60A 3ag3N-1x42A:
undetectable		 3ag3N-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.56A 3ag4A-1x42A:
undetectable		 3ag4A-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.55A 3ag4N-1x42A:
undetectable		 3ag4N-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.58A 3asnA-1x42A:
undetectable		 3asnA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.61A 3asnN-1x42A:
undetectable		 3asnN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.57A 3asoA-1x42A:
undetectable		 3asoA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.60A 3asoN-1x42A:
undetectable		 3asoN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.59A 3dtuA-1x42A:
undetectable		 3dtuA-1x42A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.61A 3dtuC-1x42A:
undetectable		 3dtuC-1x42A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		5 / 9 ASP A 123
HIS A  95
GLU A  19
HIS A  91
LEU A 129
 None
 1.24A 3hy7A-1x42A:
undetectable		 3hy7A-1x42A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KCX_A_CQLA1_0
(HYPOXIA-INDUCIBLE
FACTOR 1-ALPHA
INHIBITOR)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		5 / 10 LEU A  42
THR A  22
HIS A  95
HIS A  91
ILE A  26
 None
 1.42A 3kcxA-1x42A:
undetectable		 3kcxA-1x42A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.79A 3s33A-1x42A:
undetectable		 3s33A-1x42A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.77A 3s39A-1x42A:
undetectable		 3s39A-1x42A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.79A 3s3aA-1x42A:
undetectable		 3s3aA-1x42A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.76A 3s3bA-1x42A:
undetectable		 3s3bA-1x42A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.76A 3s3dA-1x42A:
undetectable		 3s3dA-1x42A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		5 / 12 GLY A 119
SER A 144
THR A 146
VAL A 105
LEU A 219
 None
 1.20A 3v8vA-1x42A:
undetectable		 3v8vA-1x42A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		5 / 12 LEU A 129
LEU A 133
ILE A  64
VAL A 105
GLU A  19
 None
 1.35A 3w1wB-1x42A:
2.1		 3w1wB-1x42A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.59A 3wg7A-1x42A:
undetectable		 3wg7A-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.62A 3wg7N-1x42A:
undetectable		 3wg7N-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 ASN A  86
GLU A  89
ARG A  93
 None
 0.80A 3wxoA-1x42A:
undetectable		 3wxoA-1x42A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.59A 3x2qA-1x42A:
undetectable		 3x2qA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.57A 3x2qN-1x42A:
undetectable		 3x2qN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		4 / 7 ASN A 181
GLY A 179
ILE A 121
PHE A 161
 None
 0.73A 4ejjA-1x42A:
undetectable		 4ejjA-1x42A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_1
(MEDI2452 HEAVY CHAIN
MEDI2452 LIGHT CHAIN)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		5 / 11 ILE A 121
THR A 146
SER A 148
TYR A 177
ASP A 185
 None
 1.44A 5albH-1x42A:
0.0		 5albH-1x42A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.58A 5b1aA-1x42A:
undetectable		 5b1aA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.62A 5b1aN-1x42A:
0.3		 5b1aN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.58A 5b1bA-1x42A:
undetectable		 5b1bA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.60A 5b1bN-1x42A:
undetectable		 5b1bN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.62A 5b3sA-1x42A:
undetectable		 5b3sA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.63A 5b3sN-1x42A:
undetectable		 5b3sN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.61A 5iy5A-1x42A:
undetectable		 5iy5A-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.60A 5iy5N-1x42A:
undetectable		 5iy5N-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.61A 5w97a-1x42A:
undetectable		 5w97a-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.65A 5waua-1x42A:
undetectable		 5waua-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.58A 5x19A-1x42A:
undetectable		 5x19A-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.62A 5x19N-1x42A:
undetectable		 5x19N-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.59A 5x1bA-1x42A:
undetectable		 5x1bA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.62A 5x1bN-1x42A:
undetectable		 5x1bN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.55A 5x1fA-1x42A:
undetectable		 5x1fA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.58A 5x1fN-1x42A:
undetectable		 5x1fN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.62A 5xdqA-1x42A:
undetectable		 5xdqA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.62A 5xdqN-1x42A:
undetectable		 5xdqN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.61A 5xdxA-1x42A:
undetectable		 5xdxA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.61A 5xdxN-1x42A:
undetectable		 5xdxN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		4 / 5 HIS A 117
ALA A 164
SER A 144
GLY A 119
 None
 1.19A 5yodB-1x42A:
undetectable		 5yodB-1x42A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		4 / 5 HIS A 117
ALA A 164
SER A 144
GLY A 119
 None
 1.18A 5yodD-1x42A:
undetectable		 5yodD-1x42A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.60A 5z84A-1x42A:
0.3		 5z84A-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.61A 5z84N-1x42A:
undetectable		 5z84N-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.62A 5z85A-1x42A:
0.2		 5z85A-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.60A 5z85N-1x42A:
undetectable		 5z85N-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.60A 5z86A-1x42A:
undetectable		 5z86A-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.62A 5z86N-1x42A:
undetectable		 5z86N-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.61A 5zcoA-1x42A:
0.2		 5zcoA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.57A 5zcoN-1x42A:
0.2		 5zcoN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.58A 5zcpA-1x42A:
undetectable		 5zcpA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.62A 5zcpN-1x42A:
undetectable		 5zcpN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.59A 5zcqA-1x42A:
undetectable		 5zcqA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.59A 5zcqN-1x42A:
undetectable		 5zcqN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		5 / 12 LEU A  14
GLY A  11
VAL A   5
VAL A 178
ASP A 185
 None
 1.24A 6bxlB-1x42A:
undetectable		 6bxlB-1x42A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.73A 6hu9a-1x42A:
undetectable		 6hu9a-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.74A 6hu9m-1x42A:
0.2		 6hu9m-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.63A 6nknA-1x42A:
undetectable		 6nknA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.66A 6nknN-1x42A:
undetectable		 6nknN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.59A 6nmfA-1x42A:
undetectable		 6nmfA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.60A 6nmfN-1x42A:
undetectable		 6nmfN-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.61A 6nmpA-1x42A:
undetectable		 6nmpA-1x42A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1x42 HYPOTHETICAL PROTEIN
PH0459
(Pyrococcus
horikoshii) 		3 / 3 HIS A  23
HIS A  95
HIS A  91
 None
 0.64A 6nmpN-1x42A:
undetectable		 6nmpN-1x42A:
18.44