SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x46'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1x46 HEMOGLOBIN COMPONENT
VII
(Tokunagayusurika
akamusi) 		5 / 10 ALA A 129
LEU A  14
SER A  17
LEU A 120
ALA A 124
 None
 1.00A 1g5yC-1x46A:
3.3		 1g5yC-1x46A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 1x46 HEMOGLOBIN COMPONENT
VII
(Tokunagayusurika
akamusi) 		4 / 7 ASN A 128
GLY A 130
TRP A 135
SER A  18
 None
 1.11A 2o5yH-1x46A:
undetectable
2o5yL-1x46A:
undetectable		 2o5yH-1x46A:
21.97
2o5yL-1x46A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 1x46 HEMOGLOBIN COMPONENT
VII
(Tokunagayusurika
akamusi) 		4 / 6 ASP A  11
PRO A   2
THR A   3
VAL A   5
 None
 1.10A 4yoaA-1x46A:
undetectable		 4yoaA-1x46A:
19.58