SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x48'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EYZ_A_CCSA109_0 (CELLULOSOME-RELATED PROTEIN MODULE FROM RUMINOCOCCUS FLAVEFACIENS THAT RESEMBLES PAPAIN-LIKE CYSTEINE PEPTIDASES)	1x48	INTERFERON-INDUCED, DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE (Mus musculus)	4 / 8	ASN A 13 PHE A 15 ILE A 44 ALA A 64	None	0.67A	4eyzA-1x48A: undetectable	4eyzA-1x48A: 14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EYZ_B_CCSB109_0 (CELLULOSOME-RELATED PROTEIN MODULE FROM RUMINOCOCCUS FLAVEFACIENS THAT RESEMBLES PAPAIN-LIKE CYSTEINE PEPTIDASES)	1x48	INTERFERON-INDUCED, DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE (Mus musculus)	4 / 8	ASN A 13 PHE A 15 ILE A 44 ALA A 64	None	0.68A	4eyzB-1x48A: undetectable	4eyzB-1x48A: 14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVM_A_PFLA511_1 (PROTON-GATED ION CHANNEL)	1x48	INTERFERON-INDUCED, DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE (Mus musculus)	4 / 8	ILE A 44 ALA A 16 ALA A 65 TYR A 25	None	0.75A	5mvmA-1x48A: undetectable 5mvmB-1x48A: undetectable	5mvmA-1x48A: 18.95 5mvmB-1x48A: 18.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4EYZ_A_CCSA109_0","CELLULOSOME-RELATED PROTEIN MODULE FROM RUMINOCOCCUS FLAVEFACIENS THAT RESEMBLES PAPAIN-LIKE CYSTEINE PEPTIDASES","1x48","INTERFERON-INDUCED, DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE","Mus musculus",4,"ASN A  13;PHE A  15;ILE A  44;ALA A  64","None","0.67A","4eyzA-1x48A:undetectable","4eyzA-1x48A:14.35"],["4EYZ_B_CCSB109_0","CELLULOSOME-RELATED PROTEIN MODULE FROM RUMINOCOCCUS FLAVEFACIENS THAT RESEMBLES PAPAIN-LIKE CYSTEINE PEPTIDASES","1x48","INTERFERON-INDUCED, DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE","Mus musculus",4,"ASN A  13;PHE A  15;ILE A  44;ALA A  64","None","0.68A","4eyzB-1x48A:undetectable","4eyzB-1x48A:14.35"],["5MVM_A_PFLA511_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","1x48","INTERFERON-INDUCED, DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE","Mus musculus",4,"ILE A  44;ALA A  16;ALA A  65;TYR A  25","None","0.75A","5mvmA-1x48A:undetectable;5mvmB-1x48A:undetectable","5mvmA-1x48A:18.95;5mvmB-1x48A:18.95"]]