SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x4c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 1x4c SPLICING FACTOR,
ARGININE/SERINE-RICH
1
(Mus
musculus) 		3 / 3 VAL A  47
VAL A  55
TRP A  29
 None
 0.64A 1av2A-1x4cA:
undetectable
1av2B-1x4cA:
undetectable		 1av2A-1x4cA:
20.59
1av2B-1x4cA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 1x4c SPLICING FACTOR,
ARGININE/SERINE-RICH
1
(Mus
musculus) 		3 / 3 VAL A  47
VAL A  55
TRP A  29
 None
 0.84A 1w5uA-1x4cA:
undetectable
1w5uB-1x4cA:
undetectable		 1w5uA-1x4cA:
20.59
1w5uB-1x4cA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 1x4c SPLICING FACTOR,
ARGININE/SERINE-RICH
1
(Mus
musculus) 		3 / 3 VAL A  55
TRP A  29
VAL A  47
 None
 0.85A 2izqC-1x4cA:
undetectable
2izqD-1x4cA:
undetectable		 2izqC-1x4cA:
20.59
2izqD-1x4cA:
20.59