SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x4h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 1x4h RNA-BINDING PROTEIN
28
(Mus
musculus) 		5 / 10 GLY A  33
VAL A  35
LEU A  88
LEU A  23
SER A  27
 None
 1.03A 1pbcA-1x4hA:
undetectable		 1pbcA-1x4hA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 1x4h RNA-BINDING PROTEIN
28
(Mus
musculus) 		5 / 9 ASP A  26
VAL A  47
ALA A  60
SER A  24
GLY A  58
 None
 1.12A 4mm5A-1x4hA:
undetectable		 4mm5A-1x4hA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1x4h RNA-BINDING PROTEIN
28
(Mus
musculus) 		6 / 9 LEU A  32
ALA A  60
LEU A  23
LEU A  93
LEU A  36
ALA A  62
 None
 1.23A 4z91F-1x4hA:
undetectable
4z91G-1x4hA:
undetectable
4z91H-1x4hA:
undetectable
4z91I-1x4hA:
undetectable
4z91J-1x4hA:
undetectable		 4z91F-1x4hA:
17.65
4z91G-1x4hA:
17.65
4z91H-1x4hA:
17.65
4z91I-1x4hA:
17.65
4z91J-1x4hA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1x4h RNA-BINDING PROTEIN
28
(Mus
musculus) 		6 / 9 LEU A  88
LEU A  23
ALA A  60
ALA A  62
LEU A  36
ALA A  31
 None
 1.24A 4z91F-1x4hA:
undetectable
4z91G-1x4hA:
undetectable
4z91H-1x4hA:
undetectable
4z91I-1x4hA:
undetectable
4z91J-1x4hA:
undetectable		 4z91F-1x4hA:
17.65
4z91G-1x4hA:
17.65
4z91H-1x4hA:
17.65
4z91I-1x4hA:
17.65
4z91J-1x4hA:
17.65