SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x4k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 1x4k SKELETAL MUSCLE
LIM-PROTEIN 3
(Homo
sapiens) 		3 / 3 CYH A  36
HIS A  37
PHE A  34
 ZN  A 401 (-2.3A)
None
None
 1.14A 3cr4X-1x4kA:
undetectable		 3cr4X-1x4kA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 1x4k SKELETAL MUSCLE
LIM-PROTEIN 3
(Homo
sapiens) 		3 / 3 THR A  32
LYS A   1
GLU A  10
 None
None
ZN  A 201 ( 4.7A)
 0.81A 3ijdB-1x4kA:
undetectable		 3ijdB-1x4kA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1x4k SKELETAL MUSCLE
LIM-PROTEIN 3
(Homo
sapiens) 		3 / 3 GLY A  26
SER A  27
TRP A  29
 None
 0.86A 4e7cD-1x4kA:
undetectable		 4e7cD-1x4kA:
11.97