SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x53'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1x53 ACTIVATOR OF 90 KDA
HEAT SHOCK PROTEIN
ATPASE HOMOLOG 1
(Homo
sapiens) 		4 / 5 ARG A 109
MET A 106
THR A  92
LEU A  93
 None
 1.42A 3ag1J-1x53A:
undetectable		 3ag1J-1x53A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1x53 ACTIVATOR OF 90 KDA
HEAT SHOCK PROTEIN
ATPASE HOMOLOG 1
(Homo
sapiens) 		4 / 5 ARG A 109
MET A 106
THR A  92
LEU A  93
 None
 1.43A 3ag2J-1x53A:
undetectable		 3ag2J-1x53A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1x53 ACTIVATOR OF 90 KDA
HEAT SHOCK PROTEIN
ATPASE HOMOLOG 1
(Homo
sapiens) 		4 / 5 ARG A 109
MET A 106
THR A  92
LEU A  93
 None
 1.44A 3ag4J-1x53A:
undetectable		 3ag4J-1x53A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 1x53 ACTIVATOR OF 90 KDA
HEAT SHOCK PROTEIN
ATPASE HOMOLOG 1
(Homo
sapiens) 		5 / 9 ALA A  89
GLY A 110
ILE A  13
GLY A 108
ILE A  91
 None
 1.07A 4eatB-1x53A:
undetectable		 4eatB-1x53A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1x53 ACTIVATOR OF 90 KDA
HEAT SHOCK PROTEIN
ATPASE HOMOLOG 1
(Homo
sapiens) 		3 / 3 LYS A  77
LEU A  46
ILE A  74
 None
 0.82A 5kc4A-1x53A:
undetectable		 5kc4A-1x53A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1x53 ACTIVATOR OF 90 KDA
HEAT SHOCK PROTEIN
ATPASE HOMOLOG 1
(Homo
sapiens) 		4 / 5 ARG A 109
MET A 106
THR A  92
LEU A  93
 None
 1.40A 5x1bW-1x53A:
undetectable		 5x1bW-1x53A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1x53 ACTIVATOR OF 90 KDA
HEAT SHOCK PROTEIN
ATPASE HOMOLOG 1
(Homo
sapiens) 		4 / 5 ARG A 109
MET A 106
THR A  92
LEU A  93
 None
 1.40A 6nknJ-1x53A:
undetectable		 6nknJ-1x53A:
21.26