SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x57'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 1x57 ENDOTHELIAL
DIFFERENTIATION-RELA
TED FACTOR 1
(Homo
sapiens) 		4 / 5 GLY A  26
LEU A  27
THR A  28
ARG A  22
 None
 1.10A 1ekjF-1x57A:
undetectable
1ekjG-1x57A:
undetectable		 1ekjF-1x57A:
17.81
1ekjG-1x57A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1x57 ENDOTHELIAL
DIFFERENTIATION-RELA
TED FACTOR 1
(Homo
sapiens) 		5 / 11 GLY A  59
GLU A  62
ILE A  78
ASP A  73
GLY A  71
 None
 1.01A 1jg3A-1x57A:
undetectable		 1jg3A-1x57A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1x57 ENDOTHELIAL
DIFFERENTIATION-RELA
TED FACTOR 1
(Homo
sapiens) 		5 / 11 GLY A  59
GLU A  62
ILE A  78
ASP A  73
GLY A  71
 None
 0.99A 1jg3B-1x57A:
undetectable		 1jg3B-1x57A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 1x57 ENDOTHELIAL
DIFFERENTIATION-RELA
TED FACTOR 1
(Homo
sapiens) 		5 / 12 ILE A  18
GLY A  59
ILE A  36
GLU A  13
PRO A  53
 None
 1.09A 1sg9A-1x57A:
undetectable		 1sg9A-1x57A:
17.92