SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x5y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 1x5y MYOSIN BINDING
PROTEIN C, FAST-TYPE
(Mus
musculus) 		3 / 3 THR A   9
PRO A  12
TYR A  43
 None
 0.86A 2dxrA-1x5yA:
undetectable		 2dxrA-1x5yA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 1x5y MYOSIN BINDING
PROTEIN C, FAST-TYPE
(Mus
musculus) 		4 / 8 GLY A  90
THR A   9
ASN A  87
ARG A  91
 None
 1.22A 4m5mA-1x5yA:
undetectable		 4m5mA-1x5yA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 1x5y MYOSIN BINDING
PROTEIN C, FAST-TYPE
(Mus
musculus) 		3 / 3 ILE A 103
THR A 102
PRO A  74
 None
 0.63A 6ncsA-1x5yA:
undetectable		 6ncsA-1x5yA:
18.88