SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x67'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 1x67 DREBRIN-LIKE PROTEIN
(Homo
sapiens) 		3 / 3 VAL A  61
GLU A  58
GLU A  62
 None
 0.81A 2nv4A-1x67A:
undetectable		 2nv4A-1x67A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 1x67 DREBRIN-LIKE PROTEIN
(Homo
sapiens) 		3 / 3 ASN A  11
PHE A 114
TYR A  71
 None
 0.88A 4u15A-1x67A:
undetectable		 4u15A-1x67A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 1x67 DREBRIN-LIKE PROTEIN
(Homo
sapiens) 		3 / 3 LEU A 115
SER A 113
PHE A 114
 None
 0.60A 6fgcA-1x67A:
undetectable		 6fgcA-1x67A:
19.18