SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x6d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1x6d INTERLEUKIN-16
(Homo
sapiens) 		3 / 3 GLN A  89
ILE A  20
HIS A  22
 None
 0.73A 1fm9A-1x6dA:
undetectable		 1fm9A-1x6dA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 1x6d INTERLEUKIN-16
(Homo
sapiens) 		4 / 7 LEU A  75
THR A  78
GLY A  35
LEU A  33
 None
 0.95A 1gtiA-1x6dA:
undetectable		 1gtiA-1x6dA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1x6d INTERLEUKIN-16
(Homo
sapiens) 		3 / 3 GLN A  89
ILE A  20
HIS A  22
 None
 0.71A 1k74A-1x6dA:
undetectable		 1k74A-1x6dA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 1x6d INTERLEUKIN-16
(Homo
sapiens) 		6 / 11 ILE A  70
SER A  69
ALA A  55
THR A  19
VAL A  46
VAL A  67
 None
 1.16A 3kw4A-1x6dA:
undetectable		 3kw4A-1x6dA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 1x6d INTERLEUKIN-16
(Homo
sapiens) 		3 / 3 THR A  19
PRO A  93
ARG A  94
 None
 0.77A 5nd7B-1x6dA:
undetectable		 5nd7B-1x6dA:
16.62