SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x6f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_A_ACTA502_0 (RNA POLYMERASE 3D-POL)	1x6f	ZINC FINGER PROTEIN 462 (Homo sapiens)	3 / 3	ARG A 55 LYS A 54 LYS A 57	None	1.32A	4k50A-1x6fA: undetectable	4k50A-1x6fA: 11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_E_ACTE502_0 (RNA POLYMERASE 3D-POL)	1x6f	ZINC FINGER PROTEIN 462 (Homo sapiens)	3 / 3	ARG A 55 LYS A 54 LYS A 57	None	1.30A	4k50E-1x6fA: undetectable	4k50E-1x6fA: 11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_I_ACTI506_0 (RNA POLYMERASE 3D-POL)	1x6f	ZINC FINGER PROTEIN 462 (Homo sapiens)	3 / 3	ARG A 55 LYS A 54 LYS A 57	None	1.36A	4k50I-1x6fA: undetectable	4k50I-1x6fA: 11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_A_LEUA602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	1x6f	ZINC FINGER PROTEIN 462 (Homo sapiens)	4 / 5	THR A 42 ALA A 39 THR A 38 TYR A 26	None	0.88A	5ecmA-1x6fA: undetectable	5ecmA-1x6fA: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_A_LEUA602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	1x6f	ZINC FINGER PROTEIN 462 (Homo sapiens)	4 / 6	THR A 42 ALA A 39 THR A 38 TYR A 26	None	0.86A	5ecoA-1x6fA: undetectable	5ecoA-1x6fA: 11.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4K50_A_ACTA502_0","RNA POLYMERASE 3D-POL","1x6f","ZINC FINGER PROTEIN 462","Homo sapiens",3,"ARG A  55;LYS A  54;LYS A  57","None","1.32A","4k50A-1x6fA:undetectable","4k50A-1x6fA:11.99"],["4K50_E_ACTE502_0","RNA POLYMERASE 3D-POL","1x6f","ZINC FINGER PROTEIN 462","Homo sapiens",3,"ARG A  55;LYS A  54;LYS A  57","None","1.30A","4k50E-1x6fA:undetectable","4k50E-1x6fA:11.99"],["4K50_I_ACTI506_0","RNA POLYMERASE 3D-POL","1x6f","ZINC FINGER PROTEIN 462","Homo sapiens",3,"ARG A  55;LYS A  54;LYS A  57","None","1.36A","4k50I-1x6fA:undetectable","4k50I-1x6fA:11.99"],["5ECM_A_LEUA602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","1x6f","ZINC FINGER PROTEIN 462","Homo sapiens",4,"THR A  42;ALA A  39;THR A  38;TYR A  26","None","0.88A","5ecmA-1x6fA:undetectable","5ecmA-1x6fA:11.52"],["5ECO_A_LEUA602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","1x6f","ZINC FINGER PROTEIN 462","Homo sapiens",4,"THR A  42;ALA A  39;THR A  38;TYR A  26","None","0.86A","5ecoA-1x6fA:undetectable","5ecoA-1x6fA:11.52"]]