SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x75'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 1x75 DNA GYRASE SUBUNIT A
(Escherichia
coli) 		3 / 3 LEU A 417
MET A 423
ASP A 429
 None
 0.92A 3v5wA-1x75A:
undetectable		 3v5wA-1x75A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 1x75 DNA GYRASE SUBUNIT A
(Escherichia
coli) 		3 / 3 ALA A 384
VAL A 443
TYR A 448
 None
 0.58A 5zmqH-1x75A:
undetectable		 5zmqH-1x75A:
18.58