SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1x79 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		5 / 8 ILE A 280
LEU A 266
ILE A 218
GLU A 220
VAL A 221
 None
 1.27A 1linA-1x79A:
undetectable		 1linA-1x79A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 1x79 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
RAB GTPASE BINDING
EFFECTOR PROTEIN 1
(Homo
sapiens) 		3 / 3 LEU A 277
LEU A 266
MET B 563
 None
 0.74A 1ya3B-1x79A:
undetectable		 1ya3B-1x79A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 1x79 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 8 MET A 249
ASP A 247
TYR A 294
HIS A 235
 None
 1.25A 2bteA-1x79A:
5.3		 2bteA-1x79A:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 1x79 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 8 MET A 249
ASP A 247
TYR A 294
HIS A 235
 None
 1.15A 2bteD-1x79A:
3.9		 2bteD-1x79A:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 1x79 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 7 MET A 249
ASP A 247
TYR A 294
HIS A 235
 None
 1.17A 2bytA-1x79A:
3.9		 2bytA-1x79A:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 1x79 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 7 MET A 249
ASP A 247
TYR A 294
HIS A 235
 None
 1.17A 2bytD-1x79A:
3.9		 2bytD-1x79A:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1x79 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 4 LEU A 281
ARG A 214
ILE A 280
ILE A 218
 None
 1.39A 5dzk2-1x79A:
undetectable
5dzkM-1x79A:
undetectable
5dzkN-1x79A:
undetectable		 5dzk2-1x79A:
8.33
5dzkM-1x79A:
20.83
5dzkN-1x79A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 1x79 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 7 ARG A 214
ALA A 267
ILE A 218
ALA A 217
 None
 0.80A 6ma7A-1x79A:
undetectable		 6ma7A-1x79A:
15.32