SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x7f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		4 / 4 HIS A 183
LEU A 238
LEU A 241
LEU A 347
 None
 1.25A 1a4lD-1x7fA:
4.5		 1a4lD-1x7fA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A  92
ALA A  93
ASP A  94
ILE A  55
VAL A  70
 None
 0.90A 1sdtB-1x7fA:
undetectable		 1sdtB-1x7fA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 8 ALA A  27
ILE A  23
ILE A  34
GLY A   6
ILE A 225
 None
 1.44A 1sh9A-1x7fA:
undetectable		 1sh9A-1x7fA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		4 / 7 GLY A 310
PHE A 294
PRO A 295
THR A 257
 None
 1.11A 2aouB-1x7fA:
undetectable		 2aouB-1x7fA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 10 GLY A  92
ALA A  93
ASP A  94
ILE A  55
VAL A  70
 None
 0.97A 2aquA-1x7fA:
undetectable		 2aquA-1x7fA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		4 / 6 TYR A 350
ASP A 349
PHE A 346
GLU A 201
 None
 1.08A 2dttB-1x7fA:
undetectable
2dttC-1x7fA:
undetectable		 2dttB-1x7fA:
15.57
2dttC-1x7fA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A  92
ALA A  93
ASP A  94
ILE A  55
VAL A  70
 None
 1.02A 2f80A-1x7fA:
undetectable		 2f80A-1x7fA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A  92
ALA A  93
ASP A  94
ILE A  55
VAL A  70
 None
 1.01A 2f81A-1x7fA:
undetectable		 2f81A-1x7fA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_1
(PROTEASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 11 GLY A  92
ALA A  93
ASP A  94
ILE A  55
VAL A  70
 None
 0.92A 2nnpA-1x7fA:
undetectable		 2nnpA-1x7fA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 163
ASN A 122
LEU A 219
ILE A 220
LEU A 199
 None
 1.10A 3a50A-1x7fA:
undetectable		 3a50A-1x7fA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 11 ILE A 163
ASN A 122
LEU A 219
ILE A 220
LEU A 199
 None
 1.06A 3a50C-1x7fA:
undetectable		 3a50C-1x7fA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 11 ILE A 163
ASN A 122
LEU A 219
ILE A 220
LEU A 199
 None
 1.04A 3a51A-1x7fA:
undetectable		 3a51A-1x7fA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 10 GLY A  92
ALA A  93
ASP A  94
ILE A  55
VAL A  70
 None
 0.94A 3ekyA-1x7fA:
undetectable		 3ekyA-1x7fA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 226
ALA A 230
PRO A 189
ILE A 180
PRO A 151
 None
 1.08A 3jb1A-1x7fA:
undetectable		 3jb1A-1x7fA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 10 GLY A  92
ALA A  93
ASP A  94
ILE A  55
VAL A  70
 None
 0.98A 3lzvA-1x7fA:
undetectable		 3lzvA-1x7fA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 9 GLY A  92
ALA A  93
ASP A  94
ILE A  55
LEU A  68
 None
 0.93A 3ogpA-1x7fA:
undetectable		 3ogpA-1x7fA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 9 GLY A  92
ALA A  93
ASP A  94
ILE A  55
LEU A  68
 None
 0.92A 3ogpB-1x7fA:
undetectable		 3ogpB-1x7fA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 10 GLY A  92
ALA A  93
ASP A  94
ILE A  55
VAL A  70
 None
 0.97A 3oy4B-1x7fA:
undetectable		 3oy4B-1x7fA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		4 / 8 GLY A  92
ALA A  93
ASP A  94
ILE A  55
 None
 0.63A 3so9A-1x7fA:
undetectable		 3so9A-1x7fA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		4 / 7 GLY A  92
ALA A  93
ASP A  94
ILE A  55
 None
 0.55A 3t3cA-1x7fA:
undetectable		 3t3cA-1x7fA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 10 GLY A  92
ALA A  93
ASP A  94
ILE A  55
LEU A  38
 None
 0.82A 3ttpB-1x7fA:
undetectable		 3ttpB-1x7fA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 9 GLY A  92
ALA A  93
ASP A  94
ILE A  55
LEU A  38
 None
 0.81A 3u7sB-1x7fA:
undetectable		 3u7sB-1x7fA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A  92
ALA A  93
ASP A  94
ILE A  55
VAL A  70
 None
 0.91A 3ucbB-1x7fA:
undetectable		 3ucbB-1x7fA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB304_1
(CHITOSANASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		4 / 5 TYR A 350
ILE A 163
THR A 217
HIS A 147
 None
 1.44A 4oltB-1x7fA:
0.0		 4oltB-1x7fA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 9 GLY A  92
ALA A  93
ASP A  94
ILE A  55
VAL A  70
 None
 0.99A 4q1wA-1x7fA:
undetectable		 4q1wA-1x7fA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 10 GLY A  92
ALA A  93
ASP A  94
ILE A  55
VAL A  70
 None
 0.95A 4q1yA-1x7fA:
undetectable		 4q1yA-1x7fA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		4 / 6 TYR A 350
ILE A 163
THR A 217
HIS A 147
 None
 1.47A 4qwpA-1x7fA:
undetectable		 4qwpA-1x7fA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		4 / 8 ILE A  96
LEU A   9
LEU A  38
PHE A  88
 None
 0.99A 4r38B-1x7fA:
undetectable		 4r38B-1x7fA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		4 / 5 GLU A  65
GLY A   6
SER A  32
GLY A  30
 None
 1.12A 5kprA-1x7fA:
undetectable		 5kprA-1x7fA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		4 / 7 GLY A  92
ALA A  93
ASP A  94
ILE A  55
 None
 0.57A 5kqyB-1x7fA:
undetectable		 5kqyB-1x7fA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		4 / 8 GLY A  92
ALA A  93
ASP A  94
ILE A  55
 None
 0.60A 5kr1B-1x7fA:
undetectable		 5kr1B-1x7fA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 1x7f OUTER SURFACE
PROTEIN
(Bacillus
cereus) 		5 / 12 ALA A 108
THR A 111
LEU A 143
ILE A 144
LEU A  98
 None
 1.22A 6aybA-1x7fA:
undetectable		 6aybA-1x7fA:
22.81