SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 1x94 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Vibrio
cholerae) 		4 / 4 HIS A 164
VAL A  16
THR A 120
LEU A 144
 None
 1.25A 1oq5A-1x94A:
undetectable		 1oq5A-1x94A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 1x94 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Vibrio
cholerae) 		5 / 8 LEU A  66
TYR A  70
ILE A  37
ILE A 183
ILE A 182
 None
 0.87A 2bu8A-1x94A:
undetectable		 2bu8A-1x94A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 1x94 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Vibrio
cholerae) 		5 / 11 LEU A 115
ALA A 156
GLY A 122
ALA A 130
ILE A 131
 None
 1.10A 2idwA-1x94A:
undetectable		 2idwA-1x94A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 1x94 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Vibrio
cholerae) 		4 / 6 LEU A  66
TYR A  70
ILE A  37
ILE A 183
 None
 1.00A 2q8hA-1x94A:
undetectable		 2q8hA-1x94A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 1x94 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Vibrio
cholerae) 		4 / 5 ILE A 171
HIS A 175
ARG A 161
GLY A 122
 None
 1.02A 3b9mA-1x94A:
undetectable		 3b9mA-1x94A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 1x94 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Vibrio
cholerae) 		4 / 8 TYR A 104
ALA A  59
ALA A  63
THR A  67
 None
 0.82A 3l4dA-1x94A:
undetectable		 3l4dA-1x94A:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 1x94 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Vibrio
cholerae) 		4 / 8 GLY A 166
GLU A   9
GLU A  12
ALA A  13
 None
 0.88A 4rjdA-1x94A:
undetectable
4rjdB-1x94A:
undetectable		 4rjdA-1x94A:
15.71
4rjdB-1x94A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1x94 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Vibrio
cholerae) 		5 / 12 ALA A  33
ILE A 186
PHE A  62
LEU A 118
ILE A 160
 None
 1.00A 5m24A-1x94A:
0.1		 5m24A-1x94A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1x94 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE
(Vibrio
cholerae) 		5 / 9 ALA A  59
ILE A 183
ILE A 182
ILE A  37
ALA A  81
 None
 0.96A 5nunA-1x94A:
undetectable		 5nunA-1x94A:
18.89