SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x99'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1x99 LECTIN
(Xerocomellus
chrysenteron) 		4 / 6 GLY A  55
TYR A  99
GLY A  72
ASN A  96
 None
 1.07A 3e9rA-1x99A:
undetectable		 3e9rA-1x99A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1x99 LECTIN
(Xerocomellus
chrysenteron) 		4 / 6 GLY A  55
TYR A  99
GLY A  72
ASN A  96
 None
 1.00A 3e9rC-1x99A:
undetectable		 3e9rC-1x99A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 1x99 LECTIN
(Xerocomellus
chrysenteron) 		5 / 12 ILE A   7
TYR A 130
LEU A  46
VAL A  28
TYR A  99
 None
 1.29A 3ozuA-1x99A:
undetectable		 3ozuA-1x99A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1x99 LECTIN
(Xerocomellus
chrysenteron) 		3 / 3 GLY A  55
SER A  54
TRP A  79
 None
 0.88A 4e7cD-1x99A:
0.8		 4e7cD-1x99A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 1x99 LECTIN
(Xerocomellus
chrysenteron) 		4 / 7 THR A  27
GLY A  55
VAL A  71
ASN A  96
 None
 0.80A 4forA-1x99A:
undetectable		 4forA-1x99A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 1x99 LECTIN
(Xerocomellus
chrysenteron) 		5 / 10 LEU A  86
GLY A  85
SER A 120
ALA A  70
ILE A  95
 None
 0.95A 4xj7C-1x99A:
undetectable
4xj7D-1x99A:
undetectable		 4xj7C-1x99A:
20.39
4xj7D-1x99A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1x99 LECTIN
(Xerocomellus
chrysenteron) 		4 / 6 LEU A   9
VAL A  11
LEU A  57
LEU A  86
 None
 0.94A 5tudD-1x99A:
undetectable		 5tudD-1x99A:
14.60