SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1x9z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 1x9z DNA MISMATCH REPAIR
PROTEIN MUTL
(Escherichia
coli) 		4 / 6 LEU A 460
LEU A 457
LEU A 449
LEU A 599
 None
 1.04A 2ab2A-1x9zA:
undetectable		 2ab2A-1x9zA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 1x9z DNA MISMATCH REPAIR
PROTEIN MUTL
(Escherichia
coli) 		4 / 6 SER A 456
LEU A 458
ARG A 451
LEU A 439
 None
 0.93A 3f33A-1x9zA:
undetectable		 3f33A-1x9zA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 1x9z DNA MISMATCH REPAIR
PROTEIN MUTL
(Escherichia
coli) 		5 / 12 ILE A 523
ALA A 525
ILE A 557
PRO A 554
LEU A 546
 None
 1.03A 4gh8A-1x9zA:
undetectable		 4gh8A-1x9zA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1x9z DNA MISMATCH REPAIR
PROTEIN MUTL
(Escherichia
coli) 		3 / 3 ARG A 563
VAL A 462
TRP A 466
 None
 0.96A 5fvoA-1x9zA:
undetectable		 5fvoA-1x9zA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1x9z DNA MISMATCH REPAIR
PROTEIN MUTL
(Escherichia
coli) 		4 / 6 ARG A 563
ASN A 564
ASN A 556
GLN A 559
 None
 1.24A 5l6eA-1x9zA:
undetectable		 5l6eA-1x9zA:
21.48