SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xb7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
MET A 362
ARG A 372
LEU A 401
 None
 0.71A 1a28A-1xb7A:
25.5		 1a28A-1xb7A:
26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
MET A 362
ARG A 372
LEU A 401
 None
 0.64A 1a28B-1xb7A:
25.6		 1a28B-1xb7A:
26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 GLU A 301
LEU A 365
GLU A 331
LEU A 305
GLU A 303
 None
 1.42A 1a29A-1xb7A:
0.6		 1a29A-1xb7A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 GLU A 459
ALA A 474
LEU A 477
GLU A 421
GLU A 420
 None
 1.41A 1a29A-1xb7A:
0.6		 1a29A-1xb7A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AO8_A_MTXA170_1
(DIHYDROFOLATE
REDUCTASE)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 ALA A 292
LEU A 282
PHE A 286
LEU A 447
ALA A 454
 None
 1.11A 1ao8A-1xb7A:
undetectable		 1ao8A-1xb7A:
18.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		4 / 8 ALA A 454
GLU A 457
HIS A 296
LEU A 297
 None
 0.97A 1ereE-1xb7A:
28.4		 1ereE-1xb7A:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		4 / 8 GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.59A 1ereE-1xb7A:
28.4		 1ereE-1xb7A:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		4 / 8 ALA A 454
GLU A 457
HIS A 296
LEU A 297
 None
 0.96A 1ereF-1xb7A:
28.4		 1ereF-1xb7A:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		4 / 8 GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.59A 1ereF-1xb7A:
28.4		 1ereF-1xb7A:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 11 LEU A 324
LEU A 327
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.76A 1g50A-1xb7A:
27.9		 1g50A-1xb7A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.81A 1g50B-1xb7A:
27.8		 1g50B-1xb7A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 11 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.81A 1g50C-1xb7A:
28.0		 1g50C-1xb7A:
33.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
TRP A 361
MET A 362
VAL A 366
 None
 0.67A 1gs4A-1xb7A:
26.7		 1gs4A-1xb7A:
25.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 10 LEU A 324
LEU A 327
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.52A 1gwrA-1xb7A:
28.7		 1gwrA-1xb7A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GWR_B_ESTB600_1
(OESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 9 LEU A 327
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.47A 1gwrB-1xb7A:
28.4		 1gwrB-1xb7A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.52A 1pcgA-1xb7A:
28.3		 1pcgA-1xb7A:
33.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.52A 1pcgB-1xb7A:
28.2		 1pcgB-1xb7A:
33.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 GLU A 331
MET A 362
LEU A 365
ARG A 372
GLY A 489
 None
 0.88A 1qknA-1xb7A:
25.2		 1qknA-1xb7A:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
GLU A 331
MET A 362
LEU A 365
ARG A 372
 None
 0.47A 1qknA-1xb7A:
25.2		 1qknA-1xb7A:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKT_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.60A 1qktA-1xb7A:
25.1		 1qktA-1xb7A:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		8 / 12 LEU A 324
GLU A 331
MET A 362
LEU A 365
VAL A 369
ARG A 372
LEU A 401
HIS A 494
 None
 0.48A 1s9pA-1xb7A:
29.1		 1s9pA-1xb7A:
58.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		8 / 12 CYH A 325
LEU A 327
GLU A 331
MET A 362
LEU A 365
VAL A 369
ARG A 372
LEU A 401
 None
 0.55A 1s9pB-1xb7A:
29.5		 1s9pB-1xb7A:
58.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 GLU A 331
LEU A 365
VAL A 369
ARG A 372
LEU A 398
 None
 1.25A 1s9pB-1xb7A:
29.5		 1s9pB-1xb7A:
58.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		8 / 12 LEU A 324
CYH A 325
LEU A 327
GLU A 331
MET A 362
LEU A 365
VAL A 369
ARG A 372
 None
 0.41A 1s9pC-1xb7A:
28.9		 1s9pC-1xb7A:
58.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		8 / 12 LEU A 324
GLU A 331
MET A 362
LEU A 365
VAL A 369
ARG A 372
LEU A 401
HIS A 494
 None
 0.46A 1s9pD-1xb7A:
30.3		 1s9pD-1xb7A:
58.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		4 / 6 ASP A 329
VAL A 333
ILE A 336
TRP A 361
 None
 0.93A 1s9qA-1xb7A:
28.7		 1s9qA-1xb7A:
60.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 LEU A 348
ILE A 438
GLU A 453
GLU A 449
LEU A 447
 None
 1.14A 1wopA-1xb7A:
undetectable		 1wopA-1xb7A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
MET A 362
ARG A 372
LEU A 401
 None
 0.80A 1zucB-1xb7A:
25.3		 1zucB-1xb7A:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 12 LEU A 451
ALA A 429
ARG A 448
ALA A 454
PHE A 345
PHE A 286
 None
 1.29A 2ejtA-1xb7A:
undetectable		 2ejtA-1xb7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 9 LEU A 481
LEU A 483
LEU A 484
LEU A 412
ARG A 411
 None
 1.22A 2f7aA-1xb7A:
undetectable		 2f7aA-1xb7A:
21.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 12 LEU A 327
GLU A 331
MET A 362
LEU A 365
ARG A 372
HIS A 494
 None
 0.55A 2j7xA-1xb7A:
28.2		 2j7xA-1xb7A:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 ASP A 329
GLU A 331
TRP A 361
LEU A 365
ARG A 372
 None
 1.00A 2jfaB-1xb7A:
24.8		 2jfaB-1xb7A:
34.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 GLU A 331
TRP A 361
LEU A 365
ARG A 372
GLY A 489
 None
 0.77A 2jfaB-1xb7A:
24.8		 2jfaB-1xb7A:
34.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCF_A_ESTA596_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.66A 2ocfA-1xb7A:
29.0		 2ocfA-1xb7A:
28.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		4 / 6 ASP A 329
GLU A 331
TRP A 361
ARG A 372
 None
 1.07A 2ouzA-1xb7A:
24.4		 2ouzA-1xb7A:
33.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
MET A 362
VAL A 366
ARG A 372
 None
 0.55A 2q7iA-1xb7A:
26.5		 2q7iA-1xb7A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
MET A 362
VAL A 366
ARG A 372
 None
 0.50A 2q7kA-1xb7A:
26.6		 2q7kA-1xb7A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 12 LEU A 324
LEU A 327
TRP A 361
MET A 362
VAL A 366
ARG A 372
 None
 0.64A 2q7lA-1xb7A:
26.7		 2q7lA-1xb7A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 PHE A 510
ALA A 393
PHE A 495
ALA A 404
THR A 487
 None
 1.22A 2ve3B-1xb7A:
undetectable		 2ve3B-1xb7A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 327
TRP A 361
MET A 362
ARG A 372
LEU A 401
 None
 0.75A 2w8yA-1xb7A:
25.7		 2w8yA-1xb7A:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
MET A 362
ARG A 372
LEU A 401
 None
 0.62A 2w8yB-1xb7A:
25.5		 2w8yB-1xb7A:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
MET A 362
VAL A 366
ARG A 372
 None
 0.58A 2yloA-1xb7A:
26.3		 2yloA-1xb7A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		3 / 3 CYH A 325
PHE A 328
PHE A 510
 None
 1.04A 3cr5X-1xb7A:
0.0		 3cr5X-1xb7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
MET A 362
ARG A 372
LEU A 401
 None
 0.63A 3d90A-1xb7A:
25.3		 3d90A-1xb7A:
26.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
MET A 362
ARG A 372
LEU A 401
 None
 0.78A 3d90B-1xb7A:
25.4		 3d90B-1xb7A:
26.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.56A 3erdA-1xb7A:
28.4		 3erdA-1xb7A:
32.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
TRP A 361
MET A 362
ARG A 372
VAL A 498
 None
 1.13A 3gn8A-1xb7A:
25.5		 3gn8A-1xb7A:
26.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
TRP A 361
MET A 362
ARG A 372
VAL A 498
 None
 1.15A 3gn8B-1xb7A:
25.4		 3gn8B-1xb7A:
26.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 11 LEU A 324
LEU A 327
GLU A 331
ARG A 372
HIS A 494
 None
 0.58A 3hm1B-1xb7A:
28.7		 3hm1B-1xb7A:
32.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 8 HIS A 452
LEU A 451
VAL A 290
LEU A 293
LEU A 424
 None
 1.15A 3kp6A-1xb7A:
1.3
3kp6B-1xb7A:
undetectable		 3kp6A-1xb7A:
19.67
3kp6B-1xb7A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 LEU A 398
LEU A 401
GLY A 402
VAL A 369
VAL A 366
 None
 1.16A 3lxiA-1xb7A:
undetectable		 3lxiA-1xb7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 11 LEU A 398
LEU A 401
GLY A 402
VAL A 369
VAL A 366
 None
 1.14A 3lxiB-1xb7A:
undetectable		 3lxiB-1xb7A:
21.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLL_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 10 LEU A 324
LEU A 327
GLU A 331
MET A 362
ARG A 372
HIS A 494
 None
 0.64A 3ollA-1xb7A:
26.6		 3ollA-1xb7A:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLL_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 9 LEU A 324
LEU A 327
GLU A 331
MET A 362
ARG A 372
HIS A 494
 None
 0.64A 3ollB-1xb7A:
26.7		 3ollB-1xb7A:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		7 / 12 LEU A 324
LEU A 327
GLU A 331
MET A 362
LEU A 365
ARG A 372
HIS A 494
 None
 0.61A 3olsA-1xb7A:
28.5		 3olsA-1xb7A:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 12 LEU A 324
GLU A 331
MET A 362
LEU A 365
ARG A 372
HIS A 494
 None
 0.62A 3olsB-1xb7A:
27.7		 3olsB-1xb7A:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.56A 3q95A-1xb7A:
28.6		 3q95A-1xb7A:
32.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 12 LEU A 324
LEU A 327
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.55A 3q95B-1xb7A:
28.0		 3q95B-1xb7A:
32.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 11 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.57A 3uudA-1xb7A:
28.7		 3uudA-1xb7A:
32.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
MET A 362
VAL A 366
ARG A 372
 None
 0.50A 3zqtA-1xb7A:
26.4		 3zqtA-1xb7A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 9 LEU A 398
LEU A 401
GLY A 402
VAL A 369
VAL A 366
 None
 1.10A 4c9kB-1xb7A:
undetectable		 4c9kB-1xb7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		4 / 8 LEU A 398
LEU A 401
GLY A 402
VAL A 369
 None
 0.80A 4c9nA-1xb7A:
undetectable		 4c9nA-1xb7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 LEU A 398
LEU A 401
GLY A 402
VAL A 369
VAL A 366
 None
 1.10A 4c9nB-1xb7A:
0.0		 4c9nB-1xb7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 9 LEU A 398
LEU A 401
GLY A 402
VAL A 369
VAL A 366
 None
 1.16A 4c9pA-1xb7A:
undetectable		 4c9pA-1xb7A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 LEU A 398
LEU A 401
GLY A 402
VAL A 369
VAL A 366
 None
 1.18A 4c9pB-1xb7A:
undetectable		 4c9pB-1xb7A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
TRP A 361
MET A 362
ARG A 372
 None
 0.53A 4fn9B-1xb7A:
26.4		 4fn9B-1xb7A:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLW_A_TESA1001_1
(ANDROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
TRP A 361
MET A 362
VAL A 366
ARG A 372
 None
 0.63A 4hlwA-1xb7A:
26.6		 4hlwA-1xb7A:
23.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		7 / 12 LEU A 324
LEU A 327
GLU A 331
MET A 362
LEU A 365
ARG A 372
HIS A 494
 None
 0.60A 4j24A-1xb7A:
28.3		 4j24A-1xb7A:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		7 / 12 LEU A 324
LEU A 327
GLU A 331
MET A 362
LEU A 365
ARG A 372
HIS A 494
 None
 0.60A 4j24B-1xb7A:
28.6		 4j24B-1xb7A:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 12 LEU A 327
GLU A 331
MET A 362
LEU A 365
ARG A 372
HIS A 494
 None
 0.59A 4j24C-1xb7A:
28.2		 4j24C-1xb7A:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 MET A 506
LEU A 327
GLU A 331
MET A 362
LEU A 365
 None
 1.31A 4j24C-1xb7A:
28.2		 4j24C-1xb7A:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 12 LEU A 327
GLU A 331
MET A 362
ARG A 372
LEU A 405
HIS A 494
 None
 0.60A 4j24D-1xb7A:
28.1		 4j24D-1xb7A:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 12 LEU A 327
GLU A 331
MET A 362
LEU A 365
ARG A 372
HIS A 494
 None
 0.61A 4j26A-1xb7A:
28.4		 4j26A-1xb7A:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 12 LEU A 327
GLU A 331
MET A 362
LEU A 365
ARG A 372
HIS A 494
 None
 0.61A 4j26B-1xb7A:
28.3		 4j26B-1xb7A:
34.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 12 LEU A 509
LEU A 350
GLN A 353
MET A 354
GLN A 358
ALA A 516
 None
 1.43A 4ltwA-1xb7A:
26.7		 4ltwA-1xb7A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
MET A 362
VAL A 366
ARG A 372
 None
 0.52A 4ok1A-1xb7A:
26.2		 4ok1A-1xb7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
MET A 362
VAL A 366
ARG A 372
 None
 0.53A 4oktA-1xb7A:
26.4		 4oktA-1xb7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
LEU A 327
MET A 362
VAL A 366
ARG A 372
 None
 0.68A 4olmA-1xb7A:
26.2		 4olmA-1xb7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		3 / 3 LEU A 479
LEU A 367
ASN A 432
 None
 0.55A 4otwA-1xb7A:
undetectable		 4otwA-1xb7A:
24.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 12 LEU A 324
LEU A 327
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.55A 4pxmA-1xb7A:
28.5		 4pxmA-1xb7A:
32.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 11 LEU A 327
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.52A 4pxmB-1xb7A:
28.9		 4pxmB-1xb7A:
32.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		3 / 3 VAL A 294
LEU A 298
VAL A 423
 None
 0.49A 4wq4A-1xb7A:
undetectable		 4wq4A-1xb7A:
21.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 GLU A 331
TRP A 361
LEU A 365
ARG A 372
HIS A 494
 None
 0.79A 4xi3D-1xb7A:
25.4		 4xi3D-1xb7A:
32.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.48A 4zn7A-1xb7A:
28.8		 4zn7A-1xb7A:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 11 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.49A 4zn7B-1xb7A:
29.1		 4zn7B-1xb7A:
33.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 9 PHE A 328
LEU A 398
GLY A 402
VAL A 369
VAL A 366
 None
 1.29A 5cp4A-1xb7A:
undetectable		 5cp4A-1xb7A:
20.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 LEU A 327
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.53A 5dx3A-1xb7A:
28.8		 5dx3A-1xb7A:
32.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.51A 5dxbA-1xb7A:
28.9		 5dxbA-1xb7A:
32.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		4 / 8 GLU A 331
LEU A 365
ARG A 372
LEU A 492
 None
 1.15A 5dxeA-1xb7A:
29.0		 5dxeA-1xb7A:
32.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 8 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.52A 5dxeA-1xb7A:
29.0		 5dxeA-1xb7A:
32.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.56A 5dxeB-1xb7A:
29.1		 5dxeB-1xb7A:
32.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXG_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 9 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.51A 5dxgA-1xb7A:
28.8		 5dxgA-1xb7A:
32.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 11 LEU A 327
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.58A 5dxgB-1xb7A:
29.0		 5dxgB-1xb7A:
32.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 6 LEU A 324
LEU A 365
PHE A 382
LEU A 405
HIS A 494
 None
 0.71A 5gs4A-1xb7A:
28.5		 5gs4A-1xb7A:
33.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		4 / 5 LEU A 324
PHE A 382
LEU A 405
HIS A 494
 None
 0.79A 5gtrA-1xb7A:
28.3		 5gtrA-1xb7A:
33.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.58A 5hyrA-1xb7A:
28.7		 5hyrA-1xb7A:
32.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 11 LEU A 327
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.54A 5hyrB-1xb7A:
29.0		 5hyrB-1xb7A:
32.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 327
LEU A 324
ALA A 396
LEU A 401
LEU A 380
 None
 1.16A 5mwyA-1xb7A:
26.5		 5mwyA-1xb7A:
28.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		7 / 12 LEU A 324
LEU A 327
GLU A 331
MET A 362
LEU A 365
ARG A 372
LEU A 405
 None
 0.55A 5toaA-1xb7A:
26.1		 5toaA-1xb7A:
34.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		7 / 12 LEU A 327
GLU A 331
MET A 362
LEU A 365
ARG A 372
LEU A 405
HIS A 494
 None
 0.63A 5toaB-1xb7A:
25.9		 5toaB-1xb7A:
34.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		6 / 12 MET A 506
LEU A 327
GLU A 331
MET A 362
LEU A 365
LEU A 514
 None
 1.46A 5toaB-1xb7A:
25.9		 5toaB-1xb7A:
34.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 9 GLU A 331
LEU A 365
ARG A 372
GLY A 489
LEU A 492
 None
 1.33A 5wgqA-1xb7A:
28.8		 5wgqA-1xb7A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		4 / 8 GLU A 331
LEU A 365
ARG A 372
LEU A 492
 None
 1.17A 6cbzA-1xb7A:
28.5		 6cbzA-1xb7A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 8 LEU A 324
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.49A 6cbzA-1xb7A:
28.5		 6cbzA-1xb7A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 10 LEU A 327
GLU A 331
LEU A 365
ARG A 372
HIS A 494
 None
 0.55A 6cbzB-1xb7A:
28.9		 6cbzB-1xb7A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 412
LEU A 415
ALA A 429
ARG A 411
GLN A 407
 None
 0.94A 6ew0B-1xb7A:
undetectable		 6ew0B-1xb7A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 412
LEU A 415
ALA A 429
ARG A 411
GLN A 407
 None
 0.95A 6ew0D-1xb7A:
undetectable		 6ew0D-1xb7A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 412
LEU A 415
ALA A 429
ARG A 411
GLN A 407
 None
 0.95A 6ew0H-1xb7A:
undetectable		 6ew0H-1xb7A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 1xb7 STEROID HORMONE
RECEPTOR ERR1
(Homo
sapiens) 		5 / 12 LEU A 412
LEU A 415
ALA A 429
ARG A 411
GLN A 407
 None
 0.94A 6ew0I-1xb7A:
undetectable		 6ew0I-1xb7A:
18.04