SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xbf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1xbf CLOSTRIDIUM
ACETOBUTYLICUM
Q97KL0
(Clostridium
acetobutylicum) 		5 / 8 ILE A  51
LEU A 108
ILE A  99
VAL A  24
ILE A 114
 None
 1.48A 1linA-1xbfA:
undetectable		 1linA-1xbfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 1xbf CLOSTRIDIUM
ACETOBUTYLICUM
Q97KL0
(Clostridium
acetobutylicum) 		3 / 3 ASP A  68
ASP A  14
LYS A  89
 None
 1.01A 1lqtB-1xbfA:
undetectable		 1lqtB-1xbfA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 1xbf CLOSTRIDIUM
ACETOBUTYLICUM
Q97KL0
(Clostridium
acetobutylicum) 		3 / 3 ASP A  68
ASP A  14
LYS A  89
 None
 1.02A 1lquB-1xbfA:
undetectable		 1lquB-1xbfA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 1xbf CLOSTRIDIUM
ACETOBUTYLICUM
Q97KL0
(Clostridium
acetobutylicum) 		5 / 12 ASN A  22
ILE A  99
GLY A 113
ASN A  54
ILE A 114
 None
 1.06A 1q8jB-1xbfA:
undetectable		 1q8jB-1xbfA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 1xbf CLOSTRIDIUM
ACETOBUTYLICUM
Q97KL0
(Clostridium
acetobutylicum) 		3 / 3 CYH A  42
PHE A 128
PHE A  41
 None
 0.99A 3cr5X-1xbfA:
undetectable		 3cr5X-1xbfA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1xbf CLOSTRIDIUM
ACETOBUTYLICUM
Q97KL0
(Clostridium
acetobutylicum) 		5 / 12 ASN A  22
ILE A  99
GLY A 113
ASN A  54
ILE A 114
 None
 1.14A 4djfA-1xbfA:
undetectable		 4djfA-1xbfA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 1xbf CLOSTRIDIUM
ACETOBUTYLICUM
Q97KL0
(Clostridium
acetobutylicum) 		3 / 3 GLU A  81
THR A  45
HIS A  87
 None
SO4  A 201 (-3.1A)
None
 0.74A 4q15A-1xbfA:
undetectable		 4q15A-1xbfA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 1xbf CLOSTRIDIUM
ACETOBUTYLICUM
Q97KL0
(Clostridium
acetobutylicum) 		3 / 3 GLU A  81
THR A  45
HIS A  87
 None
SO4  A 201 (-3.1A)
None
 0.75A 4q15B-1xbfA:
undetectable		 4q15B-1xbfA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 1xbf CLOSTRIDIUM
ACETOBUTYLICUM
Q97KL0
(Clostridium
acetobutylicum) 		3 / 3 GLU A  81
THR A  46
HIS A  87
 None
SO4  A 201 (-3.4A)
None
 0.86A 4q15B-1xbfA:
undetectable		 4q15B-1xbfA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 1xbf CLOSTRIDIUM
ACETOBUTYLICUM
Q97KL0
(Clostridium
acetobutylicum) 		3 / 3 GLU A  81
THR A  45
HIS A  87
 None
SO4  A 201 (-3.1A)
None
 0.67A 4ydqB-1xbfA:
undetectable		 4ydqB-1xbfA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 1xbf CLOSTRIDIUM
ACETOBUTYLICUM
Q97KL0
(Clostridium
acetobutylicum) 		3 / 3 GLU A  81
THR A  46
HIS A  87
 None
SO4  A 201 (-3.4A)
None
 0.82A 4ydqB-1xbfA:
undetectable		 4ydqB-1xbfA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1xbf CLOSTRIDIUM
ACETOBUTYLICUM
Q97KL0
(Clostridium
acetobutylicum) 		3 / 3 THR A  11
GLU A 118
HIS A  44
 None
None
SO4  A 201 (-4.0A)
 0.90A 5xiqB-1xbfA:
undetectable		 5xiqB-1xbfA:
12.40