SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xc6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 GLN A 153
LEU A 731
GLY A 804
TYR A 756
GLY A 753
 None
 1.27A 1httC-1xc6A:
undetectable		 1httC-1xc6A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 ALA A 554
VAL A 551
TRP A 549
 None
 0.75A 1kqeA-1xc6A:
undetectable
1kqeE-1xc6A:
undetectable		 1kqeA-1xc6A:
1.25
1kqeE-1xc6A:
1.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 ALA A 554
VAL A 551
TRP A 549
 None
 0.77A 1kqeB-1xc6A:
undetectable
1kqeD-1xc6A:
undetectable		 1kqeB-1xc6A:
1.25
1kqeD-1xc6A:
1.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 TRP A 549
ALA A 554
VAL A 551
 None
 0.77A 1kqeB-1xc6A:
undetectable
1kqeD-1xc6A:
undetectable		 1kqeB-1xc6A:
1.25
1kqeD-1xc6A:
1.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 TRP A 549
ALA A 554
VAL A 551
 None
 0.76A 1kqeA-1xc6A:
undetectable
1kqeE-1xc6A:
undetectable		 1kqeA-1xc6A:
1.25
1kqeE-1xc6A:
1.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 TRP A 698
HIS A 736
LYS A 838
 None
IOD  A9038 ( 4.5A)
None
 1.35A 1l7xA-1xc6A:
1.7		 1l7xA-1xc6A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 ALA A 554
VAL A 551
TRP A 549
 None
 0.63A 1micA-1xc6A:
undetectable
1micB-1xc6A:
undetectable		 1micA-1xc6A:
1.97
1micB-1xc6A:
1.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 PHE A 148
TRP A  99
GLU A 103
 None
 1.02A 1mogA-1xc6A:
undetectable		 1mogA-1xc6A:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 TYR A 936
ASN A 962
TYR A 958
GLY A 960
 None
None
None
IOD  A9052 ( 4.3A)
 1.32A 1mxgA-1xc6A:
10.1		 1mxgA-1xc6A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 5 VAL A 253
SER A 235
ASP A 213
GLN A 218
 None
None
EDO  A9009 (-3.7A)
None
 1.50A 1n2xB-1xc6A:
undetectable		 1n2xB-1xc6A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 PHE A 233
ARG A 225
ALA A 224
ILE A 181
 None
 1.01A 1oniA-1xc6A:
undetectable
1oniB-1xc6A:
undetectable		 1oniA-1xc6A:
10.56
1oniB-1xc6A:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 PHE A 233
ARG A 225
ALA A 224
ILE A 181
 None
 0.96A 1oniD-1xc6A:
undetectable
1oniF-1xc6A:
undetectable		 1oniD-1xc6A:
10.56
1oniF-1xc6A:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 GLU A 323
ASN A 321
TRP A 273
 MAN  A3007 (-3.5A)
None
None
 1.22A 1r15C-1xc6A:
1.8		 1r15C-1xc6A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 GLU A 323
ASN A 321
TRP A 273
 MAN  A3007 (-3.5A)
None
None
 1.21A 1r15D-1xc6A:
1.7		 1r15D-1xc6A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 GLU A 323
ASN A 321
TRP A 273
 MAN  A3007 (-3.5A)
None
None
 1.21A 1r15E-1xc6A:
1.8		 1r15E-1xc6A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 GLU A 323
ASN A 321
TRP A 273
 MAN  A3007 (-3.5A)
None
None
 1.17A 1r15F-1xc6A:
1.7		 1r15F-1xc6A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 ARG A 134
SER A 591
TYR A 590
 None
 0.72A 1x70A-1xc6A:
1.4		 1x70A-1xc6A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 LEU A 342
LEU A 340
GLY A 387
TYR A 329
ALA A  87
 None
 1.04A 2bm9A-1xc6A:
undetectable		 2bm9A-1xc6A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 LEU A 342
LEU A 340
GLY A 387
TYR A 329
ALA A  87
 None
 1.03A 2bm9C-1xc6A:
undetectable		 2bm9C-1xc6A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 LEU A 342
LEU A 340
GLY A 387
TYR A 329
ALA A  87
 None
 1.09A 2bm9D-1xc6A:
undetectable		 2bm9D-1xc6A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 LEU A 342
LEU A 340
GLY A 387
TYR A 329
ALA A  87
 None
 1.12A 2br4C-1xc6A:
undetectable		 2br4C-1xc6A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 LEU A 342
LEU A 340
GLY A 387
TYR A 329
ALA A  87
 None
 1.17A 2br4E-1xc6A:
undetectable		 2br4E-1xc6A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 6 SER A  52
GLU A  58
SER A 591
GLN A 580
 None
 1.39A 2cl5B-1xc6A:
undetectable		 2cl5B-1xc6A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 TYR A 138
TYR A  70
HIS A 356
GLY A 355
 None
None
None
EDO  A9008 (-3.5A)
 1.17A 2ha4B-1xc6A:
undetectable		 2ha4B-1xc6A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 LYS A 330
GLY A 511
PRO A 512
 None
None
MAN  A3008 (-4.3A)
 0.94A 2hreB-1xc6A:
undetectable		 2hreB-1xc6A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 GLU A 807
TYR A 343
ILE A 139
VAL A 143
TYR A  96
 None
GAL  A9011 (-4.2A)
None
None
GAL  A9011 (-4.7A)
 1.42A 2qeoA-1xc6A:
undetectable		 2qeoA-1xc6A:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 LEU A 675
LEU A 964
VAL A 931
TYR A 958
PHE A 913
 None
 1.22A 2weyA-1xc6A:
undetectable		 2weyA-1xc6A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 5 ILE A 177
PHE A  95
PRO A 137
VAL A  55
 None
 1.27A 2ygnA-1xc6A:
undetectable		 2ygnA-1xc6A:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 ALA A 338
SER A 292
ALA A 245
PRO A 246
VAL A 298
 None
 0.99A 2zifB-1xc6A:
2.1		 2zifB-1xc6A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 6 SER A  52
GLU A  58
SER A 591
GLN A 580
 None
 1.40A 2zvjA-1xc6A:
0.2		 2zvjA-1xc6A:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 8 GLY A 302
ASN A 341
ILE A 345
PHE A 346
 None
 0.94A 3aodA-1xc6A:
undetectable		 3aodA-1xc6A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 6 THR A 478
ILE A 459
LEU A 457
THR A 452
 None
None
EDO  A9081 (-4.5A)
None
 0.72A 3deuB-1xc6A:
undetectable		 3deuB-1xc6A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 6 GLY A 729
GLU A 864
GLY A 860
ASN A 353
 None
 1.11A 3e9rC-1xc6A:
undetectable		 3e9rC-1xc6A:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 LEU A 102
ASP A  98
VAL A  97
ILE A 139
GLY A 147
 None
 1.08A 3hgiA-1xc6A:
undetectable		 3hgiA-1xc6A:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 PRO A 135
PHE A 233
ALA A 224
 None
 0.63A 3itaD-1xc6A:
0.0		 3itaD-1xc6A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 6 SER A 538
LEU A 508
ILE A 536
ALA A 519
 None
 0.88A 3kk6B-1xc6A:
0.6		 3kk6B-1xc6A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 8 PHE A  82
GLY A  89
PHE A  95
PHE A 120
 None
 1.07A 3ko0B-1xc6A:
undetectable
3ko0J-1xc6A:
undetectable		 3ko0B-1xc6A:
6.85
3ko0J-1xc6A:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 8 GLY A  89
PHE A  95
PHE A 120
PHE A  82
 None
 1.03A 3ko0K-1xc6A:
undetectable
3ko0S-1xc6A:
undetectable		 3ko0K-1xc6A:
6.85
3ko0S-1xc6A:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 GLY A  89
PHE A  95
PHE A 120
PHE A  82
 None
 1.14A 3ko0L-1xc6A:
undetectable
3ko0N-1xc6A:
undetectable		 3ko0L-1xc6A:
6.85
3ko0N-1xc6A:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 PHE A  82
GLY A  89
PHE A  95
PHE A 120
 None
 1.10A 3ko0K-1xc6A:
undetectable
3ko0S-1xc6A:
undetectable		 3ko0K-1xc6A:
6.85
3ko0S-1xc6A:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 PHE A  82
GLY A  89
PHE A  95
PHE A 120
 None
 1.13A 3ko0R-1xc6A:
undetectable
3ko0T-1xc6A:
undetectable		 3ko0R-1xc6A:
6.85
3ko0T-1xc6A:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 LEU A 457
LEU A 488
SER A 490
ASP A 479
 EDO  A9081 (-4.5A)
IOD  A9033 (-4.6A)
None
None
 1.05A 3lm8A-1xc6A:
2.5
3lm8C-1xc6A:
undetectable		 3lm8A-1xc6A:
11.11
3lm8C-1xc6A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 GLY A 358
SER A 144
GLY A 753
ASN A 350
PHE A 305
 None
None
None
None
GAL  A9011 (-4.9A)
 1.41A 3r24A-1xc6A:
undetectable		 3r24A-1xc6A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 SER A 562
GLY A 561
GLN A 559
 None
None
IOD  A9043 ( 3.6A)
 0.36A 3v4tH-1xc6A:
0.0		 3v4tH-1xc6A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 4 LEU A 397
ALA A 390
PHE A 333
ASN A  91
 None
 1.27A 3vaqA-1xc6A:
undetectable		 3vaqA-1xc6A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 4 LEU A 397
ALA A 390
PHE A 333
ASN A  91
 None
 1.27A 3vasA-1xc6A:
undetectable		 3vasA-1xc6A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 GLY A 355
GLY A 359
TYR A 360
ALA A 100
LEU A 856
 EDO  A9008 (-3.5A)
None
None
None
None
 1.16A 3vywC-1xc6A:
undetectable		 3vywC-1xc6A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 TYR A 363
GLY A 355
GLY A 359
TYR A 360
ALA A 100
 None
EDO  A9008 (-3.5A)
None
None
None
 1.08A 3vywC-1xc6A:
undetectable		 3vywC-1xc6A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 ALA A 622
PHE A 624
ILE A 369
ASP A  80
ASP A 623
 None
 1.37A 3wemA-1xc6A:
7.6		 3wemA-1xc6A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 ALA A 622
PHE A 624
ILE A 369
ASP A  80
ASP A 623
 None
 1.36A 3weoA-1xc6A:
7.0		 3weoA-1xc6A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 8 ASP A 481
GLY A 484
VAL A 565
SER A 526
 None
 0.90A 4acbB-1xc6A:
2.9
4acbC-1xc6A:
2.9		 4acbB-1xc6A:
19.86
4acbC-1xc6A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 8 GLN A1001
ASN A 962
THR A 961
TRP A 963
 None
None
IOD  A9037 ( 4.3A)
IOD  A9037 (-4.5A)
 1.13A 4d1yA-1xc6A:
undetectable
4d1yB-1xc6A:
undetectable		 4d1yA-1xc6A:
11.35
4d1yB-1xc6A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 THR A 666
ALA A 664
SER A 662
THR A 627
 None
None
IOD  A9040 (-3.0A)
None
 0.96A 4d7bA-1xc6A:
undetectable		 4d7bA-1xc6A:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 ARG A 926
THR A 754
TRP A 308
 None
 1.19A 4d7hA-1xc6A:
0.7		 4d7hA-1xc6A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 LEU A 117
ALA A 133
ILE A 220
THR A 180
 None
 0.82A 4eyrA-1xc6A:
undetectable		 4eyrA-1xc6A:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 GLY A 735
VAL A 795
PHE A 746
ILE A 760
 None
NAG  A5001 (-4.7A)
None
None
 0.85A 4fglC-1xc6A:
undetectable		 4fglC-1xc6A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 ARG A  71
HIS A  68
TYR A 363
 None
 1.23A 4fu8A-1xc6A:
undetectable		 4fu8A-1xc6A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 ARG A  71
HIS A  68
TYR A 363
 None
 1.35A 4fu9A-1xc6A:
undetectable		 4fu9A-1xc6A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 GLU A  66
HIS A  68
PRO A  69
VAL A  93
 None
 1.12A 4hvrA-1xc6A:
undetectable		 4hvrA-1xc6A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 LEU A 462
VAL A 546
ALA A 454
LEU A 567
THR A 491
 IOD  A9056 (-4.2A)
None
IOD  A9033 ( 4.4A)
None
None
 1.49A 4iarA-1xc6A:
undetectable		 4iarA-1xc6A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 PRO A 579
VAL A 602
ALA A 604
TYR A 380
 None
 1.01A 4lb2A-1xc6A:
undetectable		 4lb2A-1xc6A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 6 ASP A 777
ASN A 776
ALA A 755
ASP A 806
 None
MAN  A7007 ( 3.1A)
None
None
 1.05A 4mdaA-1xc6A:
1.7		 4mdaA-1xc6A:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 6 ASP A  49
ASN A 400
ALA A 399
TYR A 396
 None
 1.09A 4mdbA-1xc6A:
1.7		 4mdbA-1xc6A:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 ASN A 321
GLU A 378
GLU A 382
GLU A 323
 None
MAN  A3005 (-2.9A)
None
MAN  A3007 (-3.5A)
 1.35A 4mj8C-1xc6A:
undetectable		 4mj8C-1xc6A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 5 GLY A 937
LEU A 978
LEU A 964
LEU A 861
 None
 0.77A 4o8fA-1xc6A:
undetectable		 4o8fA-1xc6A:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 TYR A 363
ALA A 304
SER A 367
MET A 344
GLY A 264
 None
None
None
None
IOD  A9050 ( 3.8A)
 1.23A 4obwA-1xc6A:
undetectable		 4obwA-1xc6A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 THR A 349
GLY A 347
HIS A  68
ASN A 350
SER A 948
 None
None
None
None
EDO  A9004 (-2.9A)
 1.38A 4pooB-1xc6A:
undetectable		 4pooB-1xc6A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 GLY A 860
ASN A 353
ILE A 800
VAL A 798
ILE A 822
 None
 1.04A 4q5mA-1xc6A:
undetectable		 4q5mA-1xc6A:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 ASN A 321
GLU A 378
GLU A 382
GLU A 323
 None
MAN  A3005 (-2.9A)
None
MAN  A3007 (-3.5A)
 1.24A 4r87I-1xc6A:
undetectable		 4r87I-1xc6A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 SER A 967
TYR A 930
ASP A 801
 None
 0.86A 4rp8C-1xc6A:
undetectable		 4rp8C-1xc6A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 GLU A 299
TYR A 363
GLU A 142
 GAL  A9011 (-2.7A)
None
GAL  A9011 (-2.8A)
 0.81A 4ryaA-1xc6A:
undetectable		 4ryaA-1xc6A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 ASN A 941
PHE A 981
TYR A 895
 None
 0.80A 4u15A-1xc6A:
undetectable		 4u15A-1xc6A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 ARG A 926
THR A 754
TRP A 308
 None
 1.12A 4ug5A-1xc6A:
0.0		 4ug5A-1xc6A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 ARG A 926
THR A 754
TRP A 308
 None
 1.18A 4uglA-1xc6A:
undetectable		 4uglA-1xc6A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 TRP A  99
THR A 170
GLY A 145
LEU A 152
PRO A 149
 None
 1.49A 4uinH-1xc6A:
2.5
4uinL-1xc6A:
undetectable		 4uinH-1xc6A:
12.94
4uinL-1xc6A:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 10 ALA A 483
VAL A 482
ASP A 481
TYR A 480
SER A 393
 IOD  A9036 ( 4.3A)
None
None
EDO  A9080 (-3.7A)
EDO  A9080 (-4.4A)
 1.40A 4xp1A-1xc6A:
undetectable		 4xp1A-1xc6A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 PHE A 913
LEU A 956
LEU A 901
LEU A 903
TYR A 958
 None
 1.21A 4xumA-1xc6A:
undetectable		 4xumA-1xc6A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 7 LEU A 856
GLY A 145
GLY A 146
ILE A 139
 None
 0.73A 4yjiA-1xc6A:
undetectable		 4yjiA-1xc6A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 ALA A 573
TYR A 574
PRO A 512
 None
None
MAN  A3008 (-4.3A)
 0.66A 4zdyA-1xc6A:
undetectable		 4zdyA-1xc6A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 5 ALA A 573
TYR A 574
HIS A 435
PRO A 512
 None
None
None
MAN  A3008 (-4.3A)
 1.06A 4ze2A-1xc6A:
undetectable		 4ze2A-1xc6A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 5 SER A  52
GLU A  58
SER A 591
GLN A 580
 None
 1.40A 5fhrB-1xc6A:
undetectable		 5fhrB-1xc6A:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 ARG A 926
THR A 754
TRP A 308
 None
 1.19A 5g6cA-1xc6A:
undetectable		 5g6cA-1xc6A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_A_GCSA801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 TYR A  96
GLU A 142
GLU A 200
GLU A 299
TYR A 343
 GAL  A9011 (-4.7A)
GAL  A9011 (-2.8A)
GAL  A9011 (-2.5A)
GAL  A9011 (-2.7A)
GAL  A9011 (-4.2A)
 0.71A 5gsmA-1xc6A:
36.3		 5gsmA-1xc6A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_B_GCSB801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		5 / 12 TYR A  96
GLU A 142
GLU A 200
GLU A 299
TYR A 343
 GAL  A9011 (-4.7A)
GAL  A9011 (-2.8A)
GAL  A9011 (-2.5A)
GAL  A9011 (-2.7A)
GAL  A9011 (-4.2A)
 0.71A 5gsmB-1xc6A:
36.5		 5gsmB-1xc6A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 6 TYR A 606
ILE A  81
ARG A 373
TYR A 912
 NAG  A3001 (-4.6A)
None
None
EDO  A9004 ( 3.4A)
 1.40A 5igyA-1xc6A:
2.2		 5igyA-1xc6A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 6 GLU A 846
PRO A 106
GLY A 725
ARG A 154
 None
 1.48A 5jcnB-1xc6A:
undetectable		 5jcnB-1xc6A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 THR A 491
SER A 490
TYR A 489
 None
 0.80A 5jsdA-1xc6A:
undetectable		 5jsdA-1xc6A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 THR A 491
SER A 490
TYR A 489
 None
 0.81A 5jsdB-1xc6A:
undetectable		 5jsdB-1xc6A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 THR A 491
SER A 490
TYR A 489
 None
 0.80A 5jsdC-1xc6A:
undetectable		 5jsdC-1xc6A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 THR A 491
SER A 490
TYR A 489
 None
 0.79A 5jseA-1xc6A:
undetectable		 5jseA-1xc6A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 THR A 491
SER A 490
TYR A 489
 None
 0.78A 5jseB-1xc6A:
undetectable		 5jseB-1xc6A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 THR A 491
SER A 490
TYR A 489
 None
 0.79A 5jseC-1xc6A:
undetectable		 5jseC-1xc6A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 6 LEU A 152
THR A 706
LEU A 159
GLU A 164
 None
 0.77A 5tudD-1xc6A:
undetectable		 5tudD-1xc6A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 6 PRO A 262
GLY A 264
TYR A 261
LEU A 319
 IOD  A9026 ( 4.4A)
IOD  A9050 ( 3.8A)
GAL  A9011 (-4.1A)
None
 0.99A 5x80A-1xc6A:
undetectable
5x80B-1xc6A:
undetectable		 5x80A-1xc6A:
9.78
5x80B-1xc6A:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_2
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 4 ASP A 222
PRO A 197
GLU A 198
TYR A 166
 None
 1.28A 5xprA-1xc6A:
0.0		 5xprA-1xc6A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 SER A 677
LYS A 676
SER A 674
 None
None
IOD  A9061 ( 3.3A)
 0.84A 6az3P-1xc6A:
undetectable		 6az3P-1xc6A:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		3 / 3 LEU A 805
GLY A 752
PHE A 733
 None
 0.64A 6exiC-1xc6A:
undetectable		 6exiC-1xc6A:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 1xc6 BETA-GALACTOSIDASE
(Penicillium
sp.) 		4 / 6 GLU A 858
ARG A1007
VAL A 852
PRO A1002
 None
None
None
IOD  A9066 ( 4.9A)
 1.47A 6fgdA-1xc6A:
undetectable		 6fgdA-1xc6A:
18.36