SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xd6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 1xd6 GASTRODIANIN-4
(Gastrodia
elata) 		4 / 6 GLN A  88
ILE A  86
ARG A   3
TYR A  96
 None
 1.32A 1e73M-1xd6A:
undetectable		 1e73M-1xd6A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 1xd6 GASTRODIANIN-4
(Gastrodia
elata) 		5 / 12 TYR A  96
THR A  76
ILE A  86
ASP A   2
LEU A  16
 None
 1.27A 3lcvB-1xd6A:
undetectable		 3lcvB-1xd6A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 1xd6 GASTRODIANIN-4
(Gastrodia
elata) 		3 / 3 ASN A  77
ASP A  59
ASN A  61
 None
 0.81A 4agaA-1xd6A:
undetectable		 4agaA-1xd6A:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 1xd6 GASTRODIANIN-4
(Gastrodia
elata) 		5 / 12 ALA A  73
THR A 108
SER A  43
LEU A  31
LEU A  85
 None
 1.48A 4qztC-1xd6A:
undetectable		 4qztC-1xd6A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1xd6 GASTRODIANIN-4
(Gastrodia
elata) 		3 / 3 VAL A  63
ALA A  70
GLN A  57
 None
None
SO4  A1001 ( 4.7A)
 0.70A 6gb9A-1xd6A:
undetectable		 6gb9A-1xd6A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1xd6 GASTRODIANIN-4
(Gastrodia
elata) 		3 / 3 VAL A  94
ALA A 102
GLN A  88
 None
 0.70A 6gb9A-1xd6A:
undetectable		 6gb9A-1xd6A:
13.46