SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xe0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_B_GLYB511_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1xe0 NUCLEOPHOSMIN
(Xenopus
laevis) 		4 / 5 SER A  15
GLU A  95
LEU A 118
GLN A  43
 None
 1.23A 3pgyB-1xe0A:
undetectable		 3pgyB-1xe0A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1xe0 NUCLEOPHOSMIN
(Xenopus
laevis) 		3 / 3 LYS A  13
ARG A  47
LEU A 118
 None
 1.22A 3v4tE-1xe0A:
undetectable		 3v4tE-1xe0A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 1xe0 NUCLEOPHOSMIN
(Xenopus
laevis) 		4 / 6 PRO A  99
ILE A 101
GLY A  66
GLU A  65
 None
 1.06A 6gqiA-1xe0A:
undetectable		 6gqiA-1xe0A:
12.97