SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xe1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 1xe1 HYPOTHETICAL PROTEIN
PF0907
(Pyrococcus
furiosus) 		6 / 12 GLY A  66
ASP A  41
ILE A  43
VAL A  97
ILE A  86
ILE A  88
 None
 1.32A 1hshA-1xe1A:
undetectable		 1hshA-1xe1A:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 1xe1 HYPOTHETICAL PROTEIN
PF0907
(Pyrococcus
furiosus) 		4 / 6 LEU A 103
VAL A  31
ILE A  43
ILE A  94
 None
 0.81A 2piwA-1xe1A:
undetectable		 2piwA-1xe1A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 1xe1 HYPOTHETICAL PROTEIN
PF0907
(Pyrococcus
furiosus) 		5 / 12 GLY A  66
ASP A  41
ILE A  43
VAL A  97
ILE A  88
 None
 0.86A 2rkgB-1xe1A:
undetectable		 2rkgB-1xe1A:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 1xe1 HYPOTHETICAL PROTEIN
PF0907
(Pyrococcus
furiosus) 		5 / 9 ASP A  84
ALA A  80
ILE A  88
GLY A  27
ILE A  86
 None
 1.03A 3nu4A-1xe1A:
undetectable		 3nu4A-1xe1A:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 1xe1 HYPOTHETICAL PROTEIN
PF0907
(Pyrococcus
furiosus) 		5 / 9 ASP A  84
ALA A  80
ILE A  88
GLY A  27
ILE A  86
 None
 0.97A 3s45A-1xe1A:
undetectable		 3s45A-1xe1A:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 1xe1 HYPOTHETICAL PROTEIN
PF0907
(Pyrococcus
furiosus) 		5 / 12 GLY A  66
ASP A  41
ILE A  43
VAL A  97
GLY A  60
 None
 1.10A 3s56A-1xe1A:
undetectable		 3s56A-1xe1A:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1xe1 HYPOTHETICAL PROTEIN
PF0907
(Pyrococcus
furiosus) 		4 / 8 ILE A  20
VAL A  29
LEU A 103
ILE A  43
 None
 0.87A 4r38D-1xe1A:
undetectable		 4r38D-1xe1A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 1xe1 HYPOTHETICAL PROTEIN
PF0907
(Pyrococcus
furiosus) 		6 / 12 GLY A  66
ASP A  41
ILE A  43
VAL A  97
ILE A  86
ILE A  88
 None
 1.10A 5e5jA-1xe1A:
undetectable		 5e5jA-1xe1A:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 1xe1 HYPOTHETICAL PROTEIN
PF0907
(Pyrococcus
furiosus) 		6 / 12 GLY A  66
ASP A  41
ILE A  43
VAL A  97
GLY A  60
ILE A  88
 None
 1.21A 5e5kA-1xe1A:
undetectable		 5e5kA-1xe1A:
26.61