SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xe7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_B_AZZB1211_1
(DEOXYNUCLEOSIDE
KINASE)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 12 GLU A 196
LEU A 200
PHE A 150
GLN A 112
ALA A  12
 None
 1.46A 2jj8B-1xe7A:
undetectable		 2jj8B-1xe7A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 12 GLU A 196
LEU A 200
PHE A 150
GLN A 112
ALA A  12
 None
 1.46A 2jj8C-1xe7A:
undetectable		 2jj8C-1xe7A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  36
THR A  87
PRO A  88
 None
 0.56A 2pynB-1xe7A:
undetectable		 2pynB-1xe7A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  36
THR A  87
PRO A  88
 None
 0.54A 2q64B-1xe7A:
undetectable		 2q64B-1xe7A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  36
THR A  87
PRO A  88
 None
 0.57A 2qakB-1xe7A:
undetectable		 2qakB-1xe7A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 106
ARG A 108
ILE A 163
 None
 0.57A 2xn5B-1xe7A:
undetectable		 2xn5B-1xe7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 109
GLY A 160
ASP A 158
LEU A 151
LEU A 106
 None
 1.18A 2zw9B-1xe7A:
undetectable		 2zw9B-1xe7A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  36
THR A  87
PRO A  88
 None
 0.57A 3tkgD-1xe7A:
undetectable		 3tkgD-1xe7A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 8 PRO A  63
VAL A  74
ASN A 100
ILE A  99
 None
None
EDO  A 306 (-3.7A)
None
 0.94A 3u5kC-1xe7A:
undetectable		 3u5kC-1xe7A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 8 PRO A  63
VAL A  74
ASN A 100
ILE A  99
 None
None
EDO  A 306 (-3.7A)
None
 0.93A 3u5kD-1xe7A:
undetectable		 3u5kD-1xe7A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 202
LYS A 180
PHE A 178
 None
 1.08A 5klaA-1xe7A:
undetectable		 5klaA-1xe7A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.61A 5qglA-1xe7A:
undetectable		 5qglA-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.67A 5qguA-1xe7A:
undetectable		 5qguA-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.61A 5qgvA-1xe7A:
undetectable		 5qgvA-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.63A 5qgwA-1xe7A:
undetectable		 5qgwA-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.61A 5qgxA-1xe7A:
undetectable		 5qgxA-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.61A 5qgyA-1xe7A:
undetectable		 5qgyA-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.63A 5qgzA-1xe7A:
undetectable		 5qgzA-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.64A 5qh0A-1xe7A:
undetectable		 5qh0A-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.61A 5qh1A-1xe7A:
undetectable		 5qh1A-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.62A 5qh2A-1xe7A:
undetectable		 5qh2A-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.62A 5qh3A-1xe7A:
undetectable		 5qh3A-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.63A 5qh4A-1xe7A:
undetectable		 5qh4A-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.60A 5qh5A-1xe7A:
undetectable		 5qh5A-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.64A 5qh6A-1xe7A:
undetectable		 5qh6A-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.62A 5qh7A-1xe7A:
undetectable		 5qh7A-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.67A 5qh9A-1xe7A:
undetectable		 5qh9A-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.64A 5qhcA-1xe7A:
undetectable		 5qhcA-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.66A 5qheA-1xe7A:
undetectable		 5qheA-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.64A 5qhfA-1xe7A:
undetectable		 5qhfA-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.60A 5qhgA-1xe7A:
undetectable		 5qhgA-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 136
VAL A 127
GLN A 112
 None
 0.63A 5qhhA-1xe7A:
undetectable		 5qhhA-1xe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 170
THR A  80
ILE A  82
PHE A  48
 None
ACY  A 307 (-3.5A)
ACY  A 307 ( 3.9A)
GUN  A 210 (-4.5A)
 0.83A 6f8cA-1xe7A:
undetectable		 6f8cA-1xe7A:
15.62