SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xeb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1xeb HYPOTHETICAL PROTEIN
PA0115
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 101
LEU A  52
LEU A  64
GLY A  79
PHE A 130
 None
 1.43A 1d4fD-1xebA:
undetectable		 1d4fD-1xebA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1xeb HYPOTHETICAL PROTEIN
PA0115
(Pseudomonas
aeruginosa) 		5 / 11 LEU A  43
LEU A  45
VAL A  46
MET A  53
ARG A  25
 None
 1.48A 1kt6A-1xebA:
undetectable		 1kt6A-1xebA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 1xeb HYPOTHETICAL PROTEIN
PA0115
(Pseudomonas
aeruginosa) 		4 / 7 LEU A  66
THR A  49
GLY A  42
ASP A  41
 None
 1.02A 2ddwB-1xebA:
undetectable		 2ddwB-1xebA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1xeb HYPOTHETICAL PROTEIN
PA0115
(Pseudomonas
aeruginosa) 		4 / 5 GLN A  38
THR A  49
LEU A  21
LEU A  22
 None
 1.11A 4lvcB-1xebA:
undetectable		 4lvcB-1xebA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1xeb HYPOTHETICAL PROTEIN
PA0115
(Pseudomonas
aeruginosa) 		5 / 7 GLY A  91
GLY A  93
SER A   2
LEU A  61
ALA A  87
 None
 1.38A 5o96C-1xebA:
undetectable		 5o96C-1xebA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDM_A_ADNA904_1
(ATP-CITRATE SYNTHASE)		 1xeb HYPOTHETICAL PROTEIN
PA0115
(Pseudomonas
aeruginosa) 		4 / 4 THR A  49
ASP A  68
ARG A  71
LEU A  67
 None
 1.07A 5tdmA-1xebA:
0.0		 5tdmA-1xebA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 1xeb HYPOTHETICAL PROTEIN
PA0115
(Pseudomonas
aeruginosa) 		4 / 6 THR A  49
ASP A  68
ARG A  71
LEU A  67
 None
 1.08A 5tdzA-1xebA:
undetectable		 5tdzA-1xebA:
16.36