SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xee'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NC3_A_ERMA1202_2 (CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562)	1xee	CHEMOTAXIS-INHIBITIN G PROTEIN CHIPS (Staphylococcus aureus)	4 / 6	THR A 66 LEU A 80 LEU A 76 GLU A 60	None	1.25A	4nc3A-1xeeA: undetectable	4nc3A-1xeeA: 12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OLM_A_198A1001_1 (ANDROGEN RECEPTOR)	1xee	CHEMOTAXIS-INHIBITIN G PROTEIN CHIPS (Staphylococcus aureus)	5 / 12	LEU A 38 LEU A 41 LEU A 76 MET A 62 VAL A 63	None	1.36A	4olmA-1xeeA: undetectable	4olmA-1xeeA: 16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_ACTA811_0 (GEPHYRIN)	1xee	CHEMOTAXIS-INHIBITIN G PROTEIN CHIPS (Staphylococcus aureus)	3 / 3	LEU A 49 LEU A 76 ARG A 46	None	0.66A	6fgcA-1xeeA: undetectable	6fgcA-1xeeA: 11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA810_0 (GEPHYRIN)	1xee	CHEMOTAXIS-INHIBITIN G PROTEIN CHIPS (Staphylococcus aureus)	3 / 3	LEU A 49 LEU A 76 ARG A 46	None	0.65A	6fgdA-1xeeA: undetectable	6fgdA-1xeeA: 11.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4NC3_A_ERMA1202_2","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562","1xee","CHEMOTAXIS-INHIBITING PROTEIN CHIPS","Staphylococcus aureus",4,"THR A  66;LEU A  80;LEU A  76;GLU A  60","None","1.25A","4nc3A-1xeeA:undetectable","4nc3A-1xeeA:12.20"],["4OLM_A_198A1001_1","ANDROGEN RECEPTOR","1xee","CHEMOTAXIS-INHIBITING PROTEIN CHIPS","Staphylococcus aureus",5,"LEU A  38;LEU A  41;LEU A  76;MET A  62;VAL A  63","None","1.36A","4olmA-1xeeA:undetectable","4olmA-1xeeA:16.46"],["6FGC_A_ACTA811_0","GEPHYRIN","1xee","CHEMOTAXIS-INHIBITING PROTEIN CHIPS","Staphylococcus aureus",3,"LEU A  49;LEU A  76;ARG A  46","None","0.66A","6fgcA-1xeeA:undetectable","6fgcA-1xeeA:11.22"],["6FGD_A_ACTA810_0","GEPHYRIN","1xee","CHEMOTAXIS-INHIBITING PROTEIN CHIPS","Staphylococcus aureus",3,"LEU A  49;LEU A  76;ARG A  46","None","0.65A","6fgdA-1xeeA:undetectable","6fgdA-1xeeA:11.22"]]