SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xer'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1xer FERREDOXIN
(Sulfurisphaera
tokodaii) 		4 / 5 LEU A  44
ALA A  70
ILE A  46
LYS A   1
 None
None
F3S  A 104 (-4.6A)
None
 1.14A 2othA-1xerA:
undetectable		 2othA-1xerA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1xer FERREDOXIN
(Sulfurisphaera
tokodaii) 		4 / 4 LEU A  44
ALA A  70
ILE A  46
LYS A   1
 None
None
F3S  A 104 (-4.6A)
None
 1.08A 4eixA-1xerA:
undetectable		 4eixA-1xerA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xer FERREDOXIN
(Sulfurisphaera
tokodaii) 		3 / 3 TYR A  22
ARG A   7
THR A   8
 None
 1.04A 5z84J-1xerA:
undetectable		 5z84J-1xerA:
16.50