SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xfd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		5 / 12 THR A 397
ILE A 354
ILE A 318
GLU A 380
ALA A 402
 None
None
None
None
NDG  A1404 ( 4.0A)
 1.30A 1jtxA-1xfdA:
undetectable		 1jtxA-1xfdA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 VAL A 207
TYR A 244
TYR A 215
GLY A 217
 None
 0.80A 1lweA-1xfdA:
undetectable		 1lweA-1xfdA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		3 / 3 PHE A 543
LEU A 514
LEU A 503
 None
 0.59A 1mx1E-1xfdA:
14.2		 1mx1E-1xfdA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.11A 1v54A-1xfdA:
undetectable
1v54C-1xfdA:
undetectable		 1v54A-1xfdA:
19.95
1v54C-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.11A 1v54N-1xfdA:
undetectable
1v54P-1xfdA:
undetectable		 1v54N-1xfdA:
19.95
1v54P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.11A 1v55A-1xfdA:
undetectable
1v55C-1xfdA:
undetectable		 1v55A-1xfdA:
19.95
1v55C-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.06A 1v55C-1xfdA:
undetectable
1v55N-1xfdA:
undetectable
1v55P-1xfdA:
undetectable		 1v55C-1xfdA:
15.42
1v55N-1xfdA:
19.95
1v55P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.10A 2dyrA-1xfdA:
undetectable
2dyrC-1xfdA:
undetectable		 2dyrA-1xfdA:
19.95
2dyrC-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.11A 2dyrN-1xfdA:
undetectable
2dyrP-1xfdA:
undetectable		 2dyrN-1xfdA:
19.95
2dyrP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 6 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.11A 2dysA-1xfdA:
undetectable
2dysC-1xfdA:
undetectable		 2dysA-1xfdA:
19.95
2dysC-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 6 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.11A 2dysN-1xfdA:
undetectable
2dysP-1xfdA:
undetectable		 2dysN-1xfdA:
19.95
2dysP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.12A 2eijA-1xfdA:
undetectable
2eijC-1xfdA:
undetectable		 2eijA-1xfdA:
19.95
2eijC-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.10A 2eijN-1xfdA:
undetectable
2eijP-1xfdA:
undetectable		 2eijN-1xfdA:
19.95
2eijP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.10A 2eikA-1xfdA:
undetectable
2eikC-1xfdA:
undetectable		 2eikA-1xfdA:
19.95
2eikC-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.10A 2eikN-1xfdA:
undetectable
2eikP-1xfdA:
undetectable		 2eikN-1xfdA:
19.95
2eikP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.07A 2eilA-1xfdA:
undetectable
2eilC-1xfdA:
undetectable		 2eilA-1xfdA:
19.95
2eilC-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.08A 2eilN-1xfdA:
undetectable
2eilP-1xfdA:
undetectable		 2eilN-1xfdA:
19.95
2eilP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 6 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.07A 2eimN-1xfdA:
undetectable
2eimP-1xfdA:
undetectable		 2eimN-1xfdA:
19.95
2eimP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 6 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.14A 2einA-1xfdA:
undetectable
2einC-1xfdA:
undetectable		 2einA-1xfdA:
19.95
2einC-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 TRP A 291
GLN A 403
TYR A 382
TYR A 344
 None
 1.25A 2ph9A-1xfdA:
0.0
2ph9B-1xfdA:
0.0		 2ph9A-1xfdA:
15.31
2ph9B-1xfdA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 TYR A 515
ARG A 525
ARG A 512
HIS A 462
 None
 1.21A 2vxaA-1xfdA:
0.2
2vxaC-1xfdA:
0.0
2vxaE-1xfdA:
0.2		 2vxaA-1xfdA:
7.34
2vxaC-1xfdA:
7.34
2vxaE-1xfdA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ARG A 512
TYR A 515
ARG A 525
HIS A 462
 None
 1.23A 2vxaA-1xfdA:
0.2
2vxaB-1xfdA:
undetectable
2vxaK-1xfdA:
0.1		 2vxaA-1xfdA:
7.34
2vxaB-1xfdA:
7.34
2vxaK-1xfdA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ARG A 512
TYR A 515
ARG A 525
HIS A 462
 None
 1.23A 2vxaB-1xfdA:
undetectable
2vxaC-1xfdA:
0.0
2vxaG-1xfdA:
0.1		 2vxaB-1xfdA:
7.34
2vxaC-1xfdA:
7.34
2vxaG-1xfdA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 TYR A 515
ARG A 525
ARG A 512
HIS A 462
 None
 1.22A 2vxaD-1xfdA:
undetectable
2vxaF-1xfdA:
0.2
2vxaI-1xfdA:
undetectable		 2vxaD-1xfdA:
7.34
2vxaF-1xfdA:
7.34
2vxaI-1xfdA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 HIS A 462
ARG A 512
TYR A 515
ARG A 525
 None
 1.22A 2vxaB-1xfdA:
undetectable
2vxaG-1xfdA:
0.1
2vxaH-1xfdA:
undetectable		 2vxaB-1xfdA:
7.34
2vxaG-1xfdA:
7.34
2vxaH-1xfdA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 HIS A 462
ARG A 512
TYR A 515
ARG A 525
 None
 1.22A 2vxaA-1xfdA:
0.2
2vxaK-1xfdA:
0.2
2vxaL-1xfdA:
undetectable		 2vxaA-1xfdA:
7.34
2vxaK-1xfdA:
7.34
2vxaL-1xfdA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.05A 2y69A-1xfdA:
undetectable
2y69C-1xfdA:
undetectable		 2y69A-1xfdA:
19.95
2y69C-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.10A 2y69C-1xfdA:
undetectable
2y69N-1xfdA:
undetectable
2y69P-1xfdA:
undetectable		 2y69C-1xfdA:
15.42
2y69N-1xfdA:
19.95
2y69P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 6 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.05A 2zxwA-1xfdA:
undetectable
2zxwC-1xfdA:
undetectable		 2zxwA-1xfdA:
19.95
2zxwC-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 6 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.09A 2zxwN-1xfdA:
undetectable
2zxwP-1xfdA:
undetectable		 2zxwN-1xfdA:
19.95
2zxwP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.06A 3abkA-1xfdA:
undetectable
3abkC-1xfdA:
undetectable		 3abkA-1xfdA:
19.95
3abkC-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.07A 3abkN-1xfdA:
undetectable
3abkP-1xfdA:
undetectable		 3abkN-1xfdA:
19.95
3abkP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.08A 3ablA-1xfdA:
undetectable
3ablC-1xfdA:
undetectable
3ablP-1xfdA:
undetectable		 3ablA-1xfdA:
19.95
3ablC-1xfdA:
15.42
3ablP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.06A 3ablC-1xfdA:
undetectable
3ablN-1xfdA:
undetectable
3ablP-1xfdA:
undetectable		 3ablC-1xfdA:
15.42
3ablN-1xfdA:
19.95
3ablP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.08A 3abmA-1xfdA:
undetectable
3abmC-1xfdA:
undetectable
3abmP-1xfdA:
undetectable		 3abmA-1xfdA:
19.95
3abmC-1xfdA:
15.42
3abmP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.11A 3abmN-1xfdA:
undetectable
3abmP-1xfdA:
undetectable		 3abmN-1xfdA:
19.95
3abmP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 6 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.09A 3ag1A-1xfdA:
undetectable
3ag1C-1xfdA:
undetectable		 3ag1A-1xfdA:
19.95
3ag1C-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 6 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.11A 3ag1N-1xfdA:
undetectable
3ag1P-1xfdA:
undetectable		 3ag1N-1xfdA:
19.95
3ag1P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.09A 3ag2A-1xfdA:
undetectable
3ag2C-1xfdA:
undetectable		 3ag2A-1xfdA:
19.95
3ag2C-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.10A 3ag2N-1xfdA:
undetectable
3ag2P-1xfdA:
undetectable		 3ag2N-1xfdA:
19.95
3ag2P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.06A 3ag3A-1xfdA:
undetectable
3ag3C-1xfdA:
undetectable		 3ag3A-1xfdA:
19.95
3ag3C-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.06A 3ag3N-1xfdA:
undetectable
3ag3P-1xfdA:
undetectable		 3ag3N-1xfdA:
19.95
3ag3P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.08A 3ag4A-1xfdA:
undetectable
3ag4C-1xfdA:
undetectable		 3ag4A-1xfdA:
19.95
3ag4C-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.11A 3ag4N-1xfdA:
undetectable
3ag4P-1xfdA:
undetectable		 3ag4N-1xfdA:
19.95
3ag4P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 6 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.08A 3asnA-1xfdA:
undetectable
3asnC-1xfdA:
undetectable		 3asnA-1xfdA:
19.95
3asnC-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.08A 3asnC-1xfdA:
undetectable
3asnN-1xfdA:
undetectable
3asnP-1xfdA:
undetectable		 3asnC-1xfdA:
15.42
3asnN-1xfdA:
19.95
3asnP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.09A 3asoA-1xfdA:
undetectable
3asoC-1xfdA:
undetectable
3asoP-1xfdA:
undetectable		 3asoA-1xfdA:
19.95
3asoC-1xfdA:
15.42
3asoP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.07A 3asoC-1xfdA:
undetectable
3asoN-1xfdA:
undetectable
3asoP-1xfdA:
undetectable		 3asoC-1xfdA:
15.42
3asoN-1xfdA:
19.95
3asoP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		3 / 3 HIS A 213
GLU A 294
HIS A 301
 None
 0.87A 3ba0A-1xfdA:
3.7		 3ba0A-1xfdA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		5 / 12 LEU A 298
ASN A 434
ALA A 395
VAL A 394
ILE A 297
 None
 1.12A 3czhB-1xfdA:
undetectable		 3czhB-1xfdA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 GLY A 456
PHE A 667
PHE A 460
GLY A 483
 None
 0.81A 3ko0M-1xfdA:
undetectable
3ko0P-1xfdA:
undetectable		 3ko0M-1xfdA:
8.70
3ko0P-1xfdA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 GLY A 456
PHE A 667
PHE A 460
GLY A 483
 None
 0.79A 3ko0O-1xfdA:
undetectable
3ko0Q-1xfdA:
undetectable		 3ko0O-1xfdA:
8.70
3ko0Q-1xfdA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 PHE A 460
GLY A 483
GLY A 456
PHE A 667
 None
 0.79A 3ko0M-1xfdA:
undetectable
3ko0P-1xfdA:
undetectable		 3ko0M-1xfdA:
8.70
3ko0P-1xfdA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		5 / 12 LEU A 202
VAL A 207
TYR A 244
TYR A 215
GLY A 217
 None
 1.07A 3medA-1xfdA:
undetectable
3medB-1xfdA:
undetectable		 3medA-1xfdA:
22.63
3medB-1xfdA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		3 / 3 HIS A 431
SER A 406
ASN A 434
 None
 0.66A 3s8pB-1xfdA:
undetectable		 3s8pB-1xfdA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
SER A 740
HIS A 824
TRP A 645
 None
 1.04A 3sg9B-1xfdA:
1.3		 3sg9B-1xfdA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		3 / 3 LYS A 299
GLU A 296
TRP A 291
 None
 1.37A 3v4tH-1xfdA:
undetectable		 3v4tH-1xfdA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		3 / 3 ASP A 486
GLY A 666
TYR A 461
 None
 0.77A 3w9tC-1xfdA:
undetectable		 3w9tC-1xfdA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		3 / 3 ASP A 486
GLY A 666
TYR A 461
 None
 0.77A 3w9tG-1xfdA:
2.2		 3w9tG-1xfdA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.10A 3wg7A-1xfdA:
undetectable
3wg7C-1xfdA:
undetectable
3wg7P-1xfdA:
undetectable		 3wg7A-1xfdA:
19.95
3wg7C-1xfdA:
15.42
3wg7P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.08A 3wg7C-1xfdA:
undetectable
3wg7N-1xfdA:
undetectable
3wg7P-1xfdA:
undetectable		 3wg7C-1xfdA:
15.42
3wg7N-1xfdA:
19.95
3wg7P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.07A 3x2qA-1xfdA:
undetectable
3x2qC-1xfdA:
undetectable
3x2qP-1xfdA:
undetectable		 3x2qA-1xfdA:
19.95
3x2qC-1xfdA:
15.42
3x2qP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.09A 3x2qC-1xfdA:
undetectable
3x2qN-1xfdA:
undetectable
3x2qP-1xfdA:
undetectable		 3x2qC-1xfdA:
15.42
3x2qN-1xfdA:
19.95
3x2qP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ABZ_A_T1CA1209_1
(TETRACYCLINE
REPRESSOR CLASS D)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		5 / 12 HIS A 301
SER A 214
GLN A 243
THR A 216
LEU A 254
 None
 1.41A 4abzA-1xfdA:
0.0		 4abzA-1xfdA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 THR A 800
ILE A 786
THR A 719
GLY A 715
 None
 0.94A 4eq4A-1xfdA:
undetectable		 4eq4A-1xfdA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 THR A 800
ILE A 786
THR A 719
GLY A 715
 None
 0.96A 4eqlA-1xfdA:
undetectable		 4eqlA-1xfdA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 THR A 800
ILE A 786
THR A 719
GLY A 715
 None
 0.93A 4eqlB-1xfdA:
undetectable		 4eqlB-1xfdA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		5 / 7 TYR A 515
VAL A 487
ILE A 463
ILE A 480
ALA A 517
 None
 1.39A 4lv9A-1xfdA:
undetectable		 4lv9A-1xfdA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		3 / 3 HIS A 301
VAL A 386
LEU A 298
 None
 0.73A 4m2vA-1xfdA:
undetectable		 4m2vA-1xfdA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		3 / 3 ILE A 297
ASP A 290
ARG A 401
 None
 0.80A 4pstA-1xfdA:
undetectable		 4pstA-1xfdA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 5 ILE A 742
SER A 740
HIS A 824
ASP A 629
 None
 1.31A 4rzvB-1xfdA:
undetectable		 4rzvB-1xfdA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		3 / 3 ARG A 705
ASP A 702
TYR A 622
 None
 0.96A 4yo9B-1xfdA:
undetectable		 4yo9B-1xfdA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_C_ACTC407_0
(PROTON-GATED ION
CHANNEL)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 4 ILE A 701
ILE A 610
ARG A 597
TYR A 700
 None
 1.41A 4zzcC-1xfdA:
0.0		 4zzcC-1xfdA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.09A 5b1aA-1xfdA:
undetectable
5b1aC-1xfdA:
undetectable
5b1aP-1xfdA:
undetectable		 5b1aA-1xfdA:
19.95
5b1aC-1xfdA:
15.42
5b1aP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.07A 5b1aN-1xfdA:
undetectable
5b1aP-1xfdA:
undetectable		 5b1aN-1xfdA:
19.95
5b1aP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.08A 5b1bA-1xfdA:
undetectable
5b1bC-1xfdA:
undetectable
5b1bP-1xfdA:
undetectable		 5b1bA-1xfdA:
19.95
5b1bC-1xfdA:
15.42
5b1bP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.09A 5b1bN-1xfdA:
undetectable
5b1bP-1xfdA:
undetectable		 5b1bN-1xfdA:
19.95
5b1bP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.06A 5b3sA-1xfdA:
undetectable
5b3sC-1xfdA:
undetectable
5b3sP-1xfdA:
undetectable		 5b3sA-1xfdA:
19.95
5b3sC-1xfdA:
15.42
5b3sP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.09A 5b3sN-1xfdA:
undetectable
5b3sP-1xfdA:
undetectable		 5b3sN-1xfdA:
19.95
5b3sP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		3 / 3 HIS A 431
SER A 406
ASN A 434
 None
 0.61A 5cprB-1xfdA:
undetectable		 5cprB-1xfdA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		5 / 12 VAL A 650
HIS A 653
GLU A 845
VAL A 657
GLY A 736
 None
 1.05A 5igtA-1xfdA:
undetectable		 5igtA-1xfdA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.07A 5iy5A-1xfdA:
undetectable
5iy5C-1xfdA:
undetectable		 5iy5A-1xfdA:
19.95
5iy5C-1xfdA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.09A 5iy5C-1xfdA:
undetectable
5iy5N-1xfdA:
undetectable
5iy5P-1xfdA:
undetectable		 5iy5C-1xfdA:
15.65
5iy5N-1xfdA:
19.95
5iy5P-1xfdA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ILE A 449
VAL A 487
THR A 481
ILE A 480
 None
 0.90A 5mzrE-1xfdA:
undetectable		 5mzrE-1xfdA:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 4 LEU A 673
GLY A 664
SER A 665
SER A 634
 None
 1.32A 5uunA-1xfdA:
undetectable		 5uunA-1xfdA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 4 LEU A 673
GLY A 664
SER A 665
SER A 634
 None
 1.32A 5uunB-1xfdA:
undetectable		 5uunB-1xfdA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.05A 5w97A-1xfdA:
undetectable
5w97C-1xfdA:
undetectable
5w97c-1xfdA:
undetectable		 5w97A-1xfdA:
19.95
5w97C-1xfdA:
15.42
5w97c-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.12A 5w97C-1xfdA:
undetectable
5w97a-1xfdA:
undetectable
5w97c-1xfdA:
undetectable		 5w97C-1xfdA:
15.42
5w97a-1xfdA:
19.95
5w97c-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.07A 5wauA-1xfdA:
undetectable
5wauC-1xfdA:
undetectable
5wauc-1xfdA:
undetectable		 5wauA-1xfdA:
19.95
5wauC-1xfdA:
15.42
5wauc-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.09A 5wauC-1xfdA:
undetectable
5waua-1xfdA:
undetectable
5wauc-1xfdA:
undetectable		 5wauC-1xfdA:
15.42
5waua-1xfdA:
19.95
5wauc-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.10A 5x19A-1xfdA:
undetectable
5x19C-1xfdA:
undetectable
5x19P-1xfdA:
undetectable		 5x19A-1xfdA:
19.95
5x19C-1xfdA:
15.42
5x19P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 6 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.07A 5x19N-1xfdA:
undetectable
5x19P-1xfdA:
undetectable		 5x19N-1xfdA:
19.95
5x19P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.08A 5x1bA-1xfdA:
undetectable
5x1bC-1xfdA:
undetectable
5x1bP-1xfdA:
undetectable		 5x1bA-1xfdA:
19.95
5x1bC-1xfdA:
15.42
5x1bP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 6 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.05A 5x1bN-1xfdA:
undetectable
5x1bP-1xfdA:
undetectable		 5x1bN-1xfdA:
19.95
5x1bP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.06A 5x1fA-1xfdA:
undetectable
5x1fC-1xfdA:
undetectable
5x1fP-1xfdA:
undetectable		 5x1fA-1xfdA:
19.95
5x1fC-1xfdA:
15.42
5x1fP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.05A 5x1fN-1xfdA:
undetectable
5x1fP-1xfdA:
undetectable		 5x1fN-1xfdA:
19.95
5x1fP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.07A 5xdqA-1xfdA:
undetectable
5xdqC-1xfdA:
undetectable
5xdqP-1xfdA:
undetectable		 5xdqA-1xfdA:
19.95
5xdqC-1xfdA:
15.42
5xdqP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.10A 5xdqC-1xfdA:
undetectable
5xdqN-1xfdA:
undetectable
5xdqP-1xfdA:
undetectable		 5xdqC-1xfdA:
15.42
5xdqN-1xfdA:
19.95
5xdqP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.10A 5xdxC-1xfdA:
undetectable
5xdxN-1xfdA:
undetectable
5xdxP-1xfdA:
undetectable		 5xdxC-1xfdA:
15.52
5xdxN-1xfdA:
19.95
5xdxP-1xfdA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.06A 5z84A-1xfdA:
undetectable
5z84C-1xfdA:
undetectable
5z84P-1xfdA:
undetectable		 5z84A-1xfdA:
19.95
5z84C-1xfdA:
15.42
5z84P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.08A 5z84C-1xfdA:
undetectable
5z84N-1xfdA:
undetectable
5z84P-1xfdA:
undetectable		 5z84C-1xfdA:
15.42
5z84N-1xfdA:
19.95
5z84P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.07A 5z85A-1xfdA:
undetectable
5z85C-1xfdA:
undetectable
5z85P-1xfdA:
undetectable		 5z85A-1xfdA:
19.95
5z85C-1xfdA:
15.42
5z85P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.11A 5z85C-1xfdA:
undetectable
5z85N-1xfdA:
undetectable
5z85P-1xfdA:
undetectable		 5z85C-1xfdA:
15.42
5z85N-1xfdA:
19.95
5z85P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.06A 5z86A-1xfdA:
undetectable
5z86C-1xfdA:
undetectable
5z86P-1xfdA:
undetectable		 5z86A-1xfdA:
19.95
5z86C-1xfdA:
15.42
5z86P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.10A 5z86C-1xfdA:
undetectable
5z86N-1xfdA:
undetectable
5z86P-1xfdA:
undetectable		 5z86C-1xfdA:
15.42
5z86N-1xfdA:
19.95
5z86P-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.08A 5zcoA-1xfdA:
undetectable
5zcoC-1xfdA:
undetectable
5zcoP-1xfdA:
undetectable		 5zcoA-1xfdA:
19.95
5zcoC-1xfdA:
15.42
5zcoP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.11A 5zcoC-1xfdA:
undetectable
5zcoN-1xfdA:
undetectable
5zcoP-1xfdA:
undetectable		 5zcoC-1xfdA:
15.42
5zcoN-1xfdA:
19.95
5zcoP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.06A 5zcpA-1xfdA:
undetectable
5zcpC-1xfdA:
undetectable
5zcpP-1xfdA:
undetectable		 5zcpA-1xfdA:
19.95
5zcpC-1xfdA:
15.42
5zcpP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.11A 5zcpC-1xfdA:
undetectable
5zcpN-1xfdA:
undetectable
5zcpP-1xfdA:
undetectable		 5zcpC-1xfdA:
15.42
5zcpN-1xfdA:
19.95
5zcpP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.06A 5zcqA-1xfdA:
undetectable
5zcqC-1xfdA:
undetectable
5zcqP-1xfdA:
undetectable		 5zcqA-1xfdA:
19.95
5zcqC-1xfdA:
15.42
5zcqP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.08A 5zcqN-1xfdA:
undetectable
5zcqP-1xfdA:
undetectable		 5zcqN-1xfdA:
19.95
5zcqP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		5 / 9 GLY A 664
VAL A 676
GLU A 675
GLY A 666
PRO A 632
 None
 1.34A 5zniA-1xfdA:
2.7		 5zniA-1xfdA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ILE A 601
ALA A 691
VAL A 692
MET A 695
 None
 0.86A 6hu9a-1xfdA:
undetectable
6hu9e-1xfdA:
undetectable		 6hu9a-1xfdA:
21.43
6hu9e-1xfdA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 6 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.11A 6nknA-1xfdA:
undetectable
6nknC-1xfdA:
undetectable		 6nknA-1xfdA:
19.95
6nknC-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 8 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.16A 6nknC-1xfdA:
undetectable
6nknN-1xfdA:
undetectable
6nknP-1xfdA:
undetectable		 6nknC-1xfdA:
15.42
6nknN-1xfdA:
19.95
6nknP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.06A 6nmfA-1xfdA:
undetectable
6nmfC-1xfdA:
undetectable
6nmfP-1xfdA:
undetectable		 6nmfA-1xfdA:
19.95
6nmfC-1xfdA:
15.42
6nmfP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.08A 6nmfN-1xfdA:
undetectable
6nmfP-1xfdA:
undetectable		 6nmfN-1xfdA:
19.95
6nmfP-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 6 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.05A 6nmpA-1xfdA:
undetectable
6nmpC-1xfdA:
0.0		 6nmpA-1xfdA:
19.95
6nmpC-1xfdA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens) 		4 / 7 ASP A 712
TYR A 716
TRP A 429
HIS A 431
 None
 1.15A 6nmpN-1xfdA:
undetectable
6nmpP-1xfdA:
undetectable		 6nmpN-1xfdA:
19.95
6nmpP-1xfdA:
15.42