SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xfg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		4 / 8 ARG A  22
ALA A   6
GLY A 183
ILE A  15
 None
 0.55A 1hshD-1xfgA:
undetectable		 1hshD-1xfgA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		4 / 6 TRP A 133
LEU A 111
LEU A 107
PRO A 106
 None
 1.19A 1hz4A-1xfgA:
undetectable		 1hz4A-1xfgA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 12 ILE A 189
GLY A 157
VAL A 159
ALA A 155
GLY A   2
 None
 0.94A 1kiaA-1xfgA:
undetectable		 1kiaA-1xfgA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 12 ILE A 189
GLY A 157
VAL A 159
ALA A 155
GLY A   2
 None
 0.94A 1kiaB-1xfgA:
undetectable		 1kiaB-1xfgA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 12 ILE A 189
GLY A 157
VAL A 159
ALA A 155
GLY A   2
 None
 0.93A 1kiaC-1xfgA:
undetectable		 1kiaC-1xfgA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 12 ILE A 189
GLY A 157
VAL A 159
ALA A 155
GLY A   2
 None
 0.94A 1nbhB-1xfgA:
undetectable		 1nbhB-1xfgA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 12 ILE A 189
GLY A 157
VAL A 159
ALA A 155
GLY A   2
 None
 0.99A 1nbiA-1xfgA:
undetectable		 1nbiA-1xfgA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 12 ILE A 189
GLY A 157
VAL A 159
ALA A 155
GLY A   2
 None
 0.99A 1nbiB-1xfgA:
undetectable		 1nbiB-1xfgA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 12 LEU A 152
LEU A 146
VAL A 145
LEU A 178
LEU A 206
 None
 1.04A 1s19A-1xfgA:
undetectable		 1s19A-1xfgA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		4 / 4 GLY A   2
SER A 191
VAL A  96
LEU A  20
 None
 1.03A 1yajB-1xfgA:
undetectable		 1yajB-1xfgA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 12 LEU A 206
TYR A 156
GLY A 175
SER A 176
GLU A 208
 None
NA  A5301 ( 4.6A)
ACT  A5302 ( 4.1A)
None
NA  A5301 ( 4.9A)
 1.16A 2a58A-1xfgA:
undetectable
2a58B-1xfgA:
undetectable		 2a58A-1xfgA:
23.89
2a58B-1xfgA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 12 LEU A 206
TYR A 156
GLY A 175
SER A 176
GLU A 208
 None
NA  A5301 ( 4.6A)
ACT  A5302 ( 4.1A)
None
NA  A5301 ( 4.9A)
 1.16A 2a58B-1xfgA:
undetectable
2a58C-1xfgA:
undetectable		 2a58B-1xfgA:
23.89
2a58C-1xfgA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 12 LEU A 206
TYR A 156
GLY A 175
SER A 176
GLU A 208
 None
NA  A5301 ( 4.6A)
ACT  A5302 ( 4.1A)
None
NA  A5301 ( 4.9A)
 1.17A 2a58D-1xfgA:
undetectable
2a58E-1xfgA:
undetectable		 2a58D-1xfgA:
23.89
2a58E-1xfgA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		6 / 12 ILE A   3
ALA A 195
LEU A  16
ILE A   7
LEU A 169
ILE A 189
 None
 1.47A 2d0kA-1xfgA:
undetectable		 2d0kA-1xfgA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_B_FOLB2161_0
(DIHYDROFOLATE
REDUCTASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		6 / 12 ILE A   3
ALA A 195
LEU A  16
ILE A   7
LEU A 169
ILE A 189
 None
 1.48A 2d0kB-1xfgA:
undetectable		 2d0kB-1xfgA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 10 VAL A  96
LEU A 196
LEU A  16
GLY A  19
ALA A 195
 None
 1.25A 2xf3A-1xfgA:
undetectable		 2xf3A-1xfgA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		4 / 6 VAL A  94
VAL A  89
ARG A  44
ARG A 108
 None
 1.24A 3bjwF-1xfgA:
undetectable		 3bjwF-1xfgA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		4 / 4 LEU A 130
ASP A 162
VAL A  95
THR A 158
 None
 1.21A 3cyxB-1xfgA:
undetectable		 3cyxB-1xfgA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 ALA A 195
VAL A 199
ILE A  15
GLY A   5
ILE A 189
 None
 1.20A 3el4B-1xfgA:
undetectable		 3el4B-1xfgA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 10 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.00A 3fhjA-1xfgA:
undetectable		 3fhjA-1xfgA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 10 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 0.99A 3fhjB-1xfgA:
undetectable		 3fhjB-1xfgA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 10 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.00A 3fhjC-1xfgA:
undetectable		 3fhjC-1xfgA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.00A 3fhjD-1xfgA:
undetectable		 3fhjD-1xfgA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 10 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.00A 3fhjE-1xfgA:
undetectable		 3fhjE-1xfgA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.00A 3fhjF-1xfgA:
undetectable		 3fhjF-1xfgA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.04A 3fi0A-1xfgA:
undetectable		 3fi0A-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.01A 3fi0C-1xfgA:
undetectable		 3fi0C-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.01A 3fi0D-1xfgA:
undetectable		 3fi0D-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.03A 3fi0F-1xfgA:
undetectable		 3fi0F-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		4 / 8 GLY A  68
ILE A 189
VAL A 159
VAL A  96
 None
 0.71A 3fi0G-1xfgA:
undetectable		 3fi0G-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 0.98A 3fi0H-1xfgA:
undetectable		 3fi0H-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 8 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.01A 3fi0I-1xfgA:
undetectable		 3fi0I-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.02A 3fi0J-1xfgA:
undetectable		 3fi0J-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.03A 3fi0K-1xfgA:
undetectable		 3fi0K-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.05A 3fi0L-1xfgA:
undetectable		 3fi0L-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.06A 3fi0M-1xfgA:
undetectable		 3fi0M-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.02A 3fi0N-1xfgA:
undetectable		 3fi0N-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 1.05A 3fi0O-1xfgA:
undetectable		 3fi0O-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		4 / 8 GLY A  68
ILE A 189
VAL A 159
VAL A  96
 None
 0.77A 3fi0Q-1xfgA:
undetectable		 3fi0Q-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 GLY A  68
VAL A  12
ILE A 189
VAL A 159
VAL A  96
 None
 0.98A 3fi0R-1xfgA:
undetectable		 3fi0R-1xfgA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 9 MET A 161
LEU A  63
ALA A  34
LEU A  45
VAL A  96
 None
 1.48A 3ozkA-1xfgA:
undetectable		 3ozkA-1xfgA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		4 / 5 THR A 122
GLY A  78
PRO A  80
ASN A  84
 HGA  A5300 ( 4.6A)
None
None
None
 1.05A 3u8qA-1xfgA:
undetectable		 3u8qA-1xfgA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 11 VAL A  35
ALA A  13
LEU A  63
LEU A  17
GLY A  32
 None
 1.11A 3zosA-1xfgA:
undetectable
3zosB-1xfgA:
undetectable		 3zosA-1xfgA:
22.96
3zosB-1xfgA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		6 / 12 LEU A 169
ALA A 212
ASP A 210
VAL A 219
ILE A 204
ILE A 214
 None
 1.42A 4jecA-1xfgA:
undetectable		 4jecA-1xfgA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		4 / 8 GLY A  19
THR A  72
LEU A  54
ARG A  21
 None
 1.22A 4m5mA-1xfgA:
undetectable		 4m5mA-1xfgA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 11 ALA A  13
ASP A  11
THR A  67
GLY A  68
ILE A  69
 None
 0.99A 4qgiA-1xfgA:
undetectable		 4qgiA-1xfgA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		4 / 5 GLY A 226
THR A 225
GLY A  68
LEU A 141
 None
 0.83A 5jlcA-1xfgA:
undetectable		 5jlcA-1xfgA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]
(Escherichia
coli) 		5 / 12 GLY A   5
ILE A 214
ASN A 187
VAL A 159
LEU A 178
 None
 0.75A 5wy0A-1xfgA:
undetectable		 5wy0A-1xfgA:
21.76