SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xfi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 8 ASP A 220
VAL A 317
GLY A 321
GLY A 323
 MG  A 400 (-2.7A)
None
None
None
 0.86A 1ekjE-1xfiA:
2.7
1ekjF-1xfiA:
2.6		 1ekjE-1xfiA:
21.39
1ekjF-1xfiA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 12 GLY A 223
ASN A 221
ASN A 163
ILE A 339
LEU A 337
 None
MG  A 400 (-2.8A)
None
None
None
 1.19A 1r30B-1xfiA:
undetectable		 1r30B-1xfiA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 8 ASP A 225
ILE A 164
GLY A 340
ILE A 339
 None
 0.66A 2o4nB-1xfiA:
undetectable		 2o4nB-1xfiA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 6 ILE A 254
SER A 253
ARG A 105
PHE A  49
 None
 1.09A 2q72A-1xfiA:
undetectable		 2q72A-1xfiA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 7 THR A  25
VAL A 347
VAL A 359
VAL A 196
 None
 0.91A 2qbnA-1xfiA:
undetectable		 2qbnA-1xfiA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 5 ARG A 151
ASP A 148
ILE A 208
GLU A 236
 None
 1.22A 2xrzA-1xfiA:
2.8
2xrzB-1xfiA:
3.0		 2xrzA-1xfiA:
22.22
2xrzB-1xfiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 7 ILE A 230
PHE A 203
PHE A 360
GLY A 162
 None
 1.05A 3em0B-1xfiA:
undetectable		 3em0B-1xfiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 8 ARG A 322
SER A 222
LEU A 293
PRO A 294
 None
 1.01A 3jq7B-1xfiA:
2.8		 3jq7B-1xfiA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 8 ARG A 322
SER A 222
LEU A 293
PRO A 294
 None
 0.91A 3jq7C-1xfiA:
2.6		 3jq7C-1xfiA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 6 ARG A 322
SER A 222
ASP A 118
PRO A 294
 None
 1.32A 3jqaA-1xfiA:
2.7		 3jqaA-1xfiA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 6 ARG A 322
SER A 222
ASP A 118
PRO A 294
 None
 1.30A 3jqaB-1xfiA:
3.0		 3jqaB-1xfiA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 6 ARG A 322
SER A 222
ASP A 118
PRO A 294
 None
 1.31A 3jqaC-1xfiA:
undetectable		 3jqaC-1xfiA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 6 ARG A 322
SER A 222
ASP A 118
PRO A 294
 None
 1.30A 3jqaD-1xfiA:
2.7		 3jqaD-1xfiA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 4 GLY A 223
GLU A 127
ASP A 125
ASP A 225
 None
 1.29A 3mb5A-1xfiA:
5.0		 3mb5A-1xfiA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		3 / 3 TYR A  21
ASP A  99
ASP A 297
 None
 0.83A 3r24A-1xfiA:
3.0		 3r24A-1xfiA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 12 GLY A 319
ASN A 221
LYS A 338
VAL A 359
GLY A 321
 None
MG  A 400 (-2.8A)
None
None
None
 1.10A 3sglA-1xfiA:
2.8		 3sglA-1xfiA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 5 VAL A 317
LEU A 298
VAL A 301
PHE A 218
 None
 1.03A 4lb0B-1xfiA:
undetectable		 4lb0B-1xfiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		4 / 5 ILE A 324
PHE A 233
HIS A 344
ASP A 220
 None
None
None
MG  A 400 (-2.7A)
 1.24A 4rzvB-1xfiA:
undetectable		 4rzvB-1xfiA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 12 HIS A 344
SER A  52
GLU A 325
GLY A 321
GLY A 100
 None
None
MG  A 401 (-3.4A)
None
None
 1.28A 4uilH-1xfiA:
undetectable
4uilL-1xfiA:
undetectable		 4uilH-1xfiA:
18.57
4uilL-1xfiA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 12 TYR A  21
VAL A 301
LEU A 305
ILE A 324
ILE A 296
 None
 1.08A 5hbsA-1xfiA:
undetectable		 5hbsA-1xfiA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_A_KANA600_1
(BIFUNCTIONAL AAC/APH)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 12 ASP A 256
SER A 253
ASP A 220
GLU A 108
GLU A 325
 MG  A 400 (-2.6A)
None
MG  A 400 (-2.7A)
None
MG  A 401 (-3.4A)
 1.45A 5iqbA-1xfiA:
0.0		 5iqbA-1xfiA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_B_KANB600_1
(BIFUNCTIONAL AAC/APH)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 11 ASP A 256
SER A 253
ASP A 220
GLU A 108
GLU A 325
 MG  A 400 (-2.6A)
None
MG  A 400 (-2.7A)
None
MG  A 401 (-3.4A)
 1.43A 5iqbB-1xfiA:
2.0		 5iqbB-1xfiA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_D_KAND600_1
(BIFUNCTIONAL AAC/APH)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 12 ASP A 256
SER A 253
ASP A 220
GLU A 108
GLU A 325
 MG  A 400 (-2.6A)
None
MG  A 400 (-2.7A)
None
MG  A 401 (-3.4A)
 1.34A 5iqbD-1xfiA:
2.5		 5iqbD-1xfiA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQC_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 10 ASP A 256
SER A 253
ASP A 220
GLU A 108
GLU A 325
 MG  A 400 (-2.6A)
None
MG  A 400 (-2.7A)
None
MG  A 401 (-3.4A)
 1.33A 5iqcA-1xfiA:
2.0		 5iqcA-1xfiA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQC_B_51GB600_1
(BIFUNCTIONAL AAC/APH)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 10 ASP A 256
SER A 253
ASP A 220
GLU A 108
GLU A 325
 MG  A 400 (-2.6A)
None
MG  A 400 (-2.7A)
None
MG  A 401 (-3.4A)
 1.44A 5iqcB-1xfiA:
2.1		 5iqcB-1xfiA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQC_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 10 ASP A 256
SER A 253
ASP A 220
GLU A 108
GLU A 325
 MG  A 400 (-2.6A)
None
MG  A 400 (-2.7A)
None
MG  A 401 (-3.4A)
 1.31A 5iqcD-1xfiA:
2.4		 5iqcD-1xfiA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 12 ASP A 256
SER A 253
ASP A 220
GLU A 108
GLU A 325
 MG  A 400 (-2.6A)
None
MG  A 400 (-2.7A)
None
MG  A 401 (-3.4A)
 1.26A 5iqeD-1xfiA:
undetectable		 5iqeD-1xfiA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQG_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 10 ASP A 256
SER A 253
ASP A 220
GLU A 108
GLU A 325
 MG  A 400 (-2.6A)
None
MG  A 400 (-2.7A)
None
MG  A 401 (-3.4A)
 1.42A 5iqgA-1xfiA:
2.0		 5iqgA-1xfiA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQG_B_51GB600_1
(BIFUNCTIONAL AAC/APH)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 10 ASP A 256
SER A 253
ASP A 220
GLU A 108
GLU A 325
 MG  A 400 (-2.6A)
None
MG  A 400 (-2.7A)
None
MG  A 401 (-3.4A)
 1.33A 5iqgB-1xfiA:
2.1		 5iqgB-1xfiA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQG_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 10 ASP A 256
SER A 253
ASP A 220
GLU A 108
GLU A 325
 MG  A 400 (-2.6A)
None
MG  A 400 (-2.7A)
None
MG  A 401 (-3.4A)
 1.35A 5iqgD-1xfiA:
0.0		 5iqgD-1xfiA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 12 ILE A 208
ILE A 230
ALA A 234
LEU A 237
ALA A 242
 None
 1.09A 5oy02-1xfiA:
2.4		 5oy02-1xfiA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 10 ILE A 208
ILE A 230
ALA A 234
LEU A 237
ALA A 242
 None
 1.17A 5zjiB-1xfiA:
undetectable		 5zjiB-1xfiA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 12 ILE A 286
LEU A 305
VAL A 216
LEU A 266
LEU A 276
 None
 1.20A 6b54A-1xfiA:
undetectable		 6b54A-1xfiA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		3 / 3 ILE A 254
ASN A 291
CYH A 259
 None
 0.84A 6bp4A-1xfiA:
undetectable		 6bp4A-1xfiA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 12 VAL A 301
GLY A 290
PHE A 218
SER A 309
VAL A 317
 None
 1.12A 6bqgA-1xfiA:
2.6		 6bqgA-1xfiA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 9 GLY A 352
GLY A 353
VAL A 191
GLU A 346
CYH A 358
 None
 1.38A 6gnfA-1xfiA:
3.6		 6gnfA-1xfiA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 11 LEU A 237
GLY A 229
ILE A 159
ILE A 316
ILE A 217
 None
 0.97A 6gp2A-1xfiA:
undetectable		 6gp2A-1xfiA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 11 LEU A 237
GLY A 229
ILE A 159
ILE A 316
ILE A 217
 None
 0.97A 6gp2B-1xfiA:
undetectable		 6gp2B-1xfiA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 1xfi UNKNOWN PROTEIN
(Arabidopsis
thaliana) 		5 / 12 PHE A 233
GLY A 229
LEU A 228
ILE A 316
VAL A 139
 None
 1.00A 6mhtA-1xfiA:
2.7		 6mhtA-1xfiA:
22.42