SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xfr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_0
(N,N-DIMETHYLGLYCINE
OXIDASE)		 1xfr PHEROMONE-BINDING
PROTEIN
(Bombyx
mori) 		5 / 12 MET A  23
LEU A  25
ASN A  45
PHE A  12
LEU A  55
 None
 1.28A 1pj7A-1xfrA:
undetectable		 1pj7A-1xfrA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_A_DESA129_1
(TRANSTHYRETIN)		 1xfr PHEROMONE-BINDING
PROTEIN
(Bombyx
mori) 		4 / 4 LYS A  20
LEU A  16
LEU A  55
SER A  56
 None
 1.46A 1tt6A-1xfrA:
undetectable		 1tt6A-1xfrA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1xfr PHEROMONE-BINDING
PROTEIN
(Bombyx
mori) 		4 / 6 LEU A  55
MET A  23
THR A  24
LEU A  25
 None
 1.05A 1v54A-1xfrA:
undetectable
1v54J-1xfrA:
undetectable		 1v54A-1xfrA:
11.86
1v54J-1xfrA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 1xfr PHEROMONE-BINDING
PROTEIN
(Bombyx
mori) 		4 / 8 GLY A  49
ALA A  51
ASN A  45
ILE A  29
 None
 0.84A 2dtjA-1xfrA:
undetectable
2dtjB-1xfrA:
undetectable		 2dtjA-1xfrA:
22.47
2dtjB-1xfrA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1xfr PHEROMONE-BINDING
PROTEIN
(Bombyx
mori) 		4 / 6 LEU A  55
MET A  23
THR A  24
LEU A  25
 None
 1.05A 2dyrA-1xfrA:
undetectable
2dyrJ-1xfrA:
undetectable		 2dyrA-1xfrA:
11.86
2dyrJ-1xfrA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1xfr PHEROMONE-BINDING
PROTEIN
(Bombyx
mori) 		4 / 6 LEU A  55
MET A  23
THR A  24
LEU A  25
 None
 1.06A 2dysA-1xfrA:
undetectable
2dysJ-1xfrA:
undetectable		 2dysA-1xfrA:
11.86
2dysJ-1xfrA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1xfr PHEROMONE-BINDING
PROTEIN
(Bombyx
mori) 		4 / 7 LEU A  55
MET A  23
THR A  24
LEU A  25
 None
 1.07A 2eikA-1xfrA:
undetectable
2eikJ-1xfrA:
undetectable		 2eikA-1xfrA:
11.86
2eikJ-1xfrA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1xfr PHEROMONE-BINDING
PROTEIN
(Bombyx
mori) 		4 / 6 LEU A  55
MET A  23
THR A  24
LEU A  25
 None
 1.10A 2zxwA-1xfrA:
undetectable
2zxwJ-1xfrA:
undetectable		 2zxwA-1xfrA:
11.86
2zxwJ-1xfrA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1xfr PHEROMONE-BINDING
PROTEIN
(Bombyx
mori) 		4 / 6 LEU A  55
MET A  23
THR A  24
LEU A  25
 None
 1.05A 3abmA-1xfrA:
undetectable
3abmJ-1xfrA:
undetectable		 3abmA-1xfrA:
11.86
3abmJ-1xfrA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1xfr PHEROMONE-BINDING
PROTEIN
(Bombyx
mori) 		4 / 6 LEU A  55
MET A  23
THR A  24
LEU A  25
 None
 1.08A 3asnA-1xfrA:
undetectable
3asnJ-1xfrA:
undetectable		 3asnA-1xfrA:
11.86
3asnJ-1xfrA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 1xfr PHEROMONE-BINDING
PROTEIN
(Bombyx
mori) 		5 / 12 PHE A 118
ILE A 122
LEU A 125
ALA A  77
VAL A  94
 None
 1.06A 5km9B-1xfrA:
undetectable		 5km9B-1xfrA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xfr PHEROMONE-BINDING
PROTEIN
(Bombyx
mori) 		4 / 6 LEU A  55
MET A  23
THR A  24
LEU A  25
 None
 1.05A 5x1fA-1xfrA:
undetectable
5x1fJ-1xfrA:
undetectable		 5x1fA-1xfrA:
11.86
5x1fJ-1xfrA:
25.25