SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xg0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1xg0 B-PHYCOERYTHRIN BETA
CHAIN
(Rhodomonas
sp.
CS24) 		3 / 3 LEU C  90
VAL C  93
LEU C  97
 None
 0.44A 1mz9B-1xg0C:
undetectable		 1mz9B-1xg0C:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 1xg0 B-PHYCOERYTHRIN BETA
CHAIN
(Rhodomonas
sp.
CS24) 		4 / 4 SER C  32
ILE C  31
VAL C  41
THR C 153
 None
None
None
PEB  C 258 (-4.3A)
 1.21A 1u70A-1xg0C:
undetectable		 1u70A-1xg0C:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1xg0 B-PHYCOERYTHRIN BETA
CHAIN
(Rhodomonas
sp.
CS24) 		3 / 3 SER C  46
ASP C  39
CYH C 158
 None
PEB  C 258 (-3.1A)
PEB  C 258 (-1.8A)
 0.99A 2br4E-1xg0C:
undetectable		 2br4E-1xg0C:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 1xg0 B-PHYCOERYTHRIN BETA
CHAIN
(Rhodomonas
sp.
CS24) 		5 / 12 VAL C 165
ALA C 162
LEU C 161
SER C  40
VAL C  41
 None
None
None
PEB  C 258 (-3.1A)
None
 1.23A 2c12C-1xg0C:
undetectable		 2c12C-1xg0C:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 1xg0 B-PHYCOERYTHRIN BETA
CHAIN
(Rhodomonas
sp.
CS24) 		5 / 12 CYH C  73
LEU C  66
ASN C 125
ALA C 130
VAL C  56
 PEB  C 282 (-3.5A)
PEB  C 282 ( 4.8A)
None
PEB  C 282 ( 3.9A)
None
 1.23A 4x1iB-1xg0C:
undetectable		 4x1iB-1xg0C:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 1xg0 B-PHYCOERYTHRIN BETA
CHAIN
(Rhodomonas
sp.
CS24) 		5 / 12 GLY C 121
ASN C  63
CYH C  73
CYH C  82
LEU C  66
 MEN  C  72 ( 4.5A)
None
PEB  C 282 (-3.5A)
PEB  C 282 (-1.8A)
PEB  C 282 ( 4.8A)
 1.36A 5lsuA-1xg0C:
undetectable		 5lsuA-1xg0C:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 1xg0 PHYCOERYTHRIN
ALPHA-3 CHAIN
B-PHYCOERYTHRIN BETA
CHAIN
(Rhodomonas
sp.
CS24;
Rhodomonas
sp.
CS24) 		5 / 12 ILE C  31
ALA A  31
LEU C  38
ARG A  17
ASP A  35
 None
None
PEB  C 258 (-4.2A)
PEB  C 258 (-3.0A)
None
 1.19A 6ie8A-1xg0C:
undetectable		 6ie8A-1xg0C:
19.40