SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xhd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		3 / 3 VAL A  57
VAL A  77
TRP A  37
 None
 0.86A 1bdwA-1xhdA:
undetectable
1bdwB-1xhdA:
undetectable		 1bdwA-1xhdA:
9.78
1bdwB-1xhdA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		5 / 11 ALA A 112
ILE A  96
GLY A  97
GLY A 115
ILE A 126
 None
 0.78A 1sduA-1xhdA:
undetectable		 1sduA-1xhdA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		5 / 10 ALA A 112
ILE A  96
GLY A  97
GLY A 115
ILE A 126
 None
 0.82A 1sdvA-1xhdA:
undetectable		 1sdvA-1xhdA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		5 / 12 ALA A 112
ILE A  96
GLY A  97
GLY A 115
ILE A 126
 None
 0.73A 2avvD-1xhdA:
undetectable		 2avvD-1xhdA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		5 / 8 LEU A  85
ILE A  90
LEU A  73
THR A  49
LEU A  71
 None
 1.50A 2xfhA-1xhdA:
undetectable		 2xfhA-1xhdA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		4 / 7 GLN A  65
VAL A  28
ILE A  42
THR A  49
 None
 0.71A 2xrzB-1xhdA:
undetectable		 2xrzB-1xhdA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		5 / 12 ALA A 112
ILE A  96
GLY A  97
GLY A 115
ILE A 126
 None
 0.74A 3cyxB-1xhdA:
undetectable		 3cyxB-1xhdA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		5 / 12 SER A 100
GLY A  97
GLY A 134
GLY A 117
ILE A 140
 None
 0.93A 3gczA-1xhdA:
undetectable		 3gczA-1xhdA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		6 / 12 LEU A  73
ILE A 108
ILE A 126
ILE A 101
VAL A  79
ILE A  90
 None
 1.46A 4q1xB-1xhdA:
undetectable		 4q1xB-1xhdA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		4 / 5 ILE A  84
PHE A 113
CYH A  88
HIS A  64
 None
None
None
SO4  A 201 (-3.6A)
 1.36A 4rzvA-1xhdA:
undetectable		 4rzvA-1xhdA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		4 / 6 GLY A  26
THR A  25
VAL A  28
HIS A  64
 None
None
None
SO4  A 201 (-3.6A)
 0.99A 5ewuA-1xhdA:
undetectable		 5ewuA-1xhdA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		4 / 6 GLY A  26
THR A  25
VAL A  28
HIS A  64
 None
None
None
SO4  A 201 (-3.6A)
 1.05A 5ewuB-1xhdA:
undetectable		 5ewuB-1xhdA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		5 / 12 ASP A  76
ASP A  93
SER A  15
GLU A  32
GLU A  33
 None
 1.40A 5iqeC-1xhdA:
0.0		 5iqeC-1xhdA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE
(Bacillus
cereus) 		4 / 6 SER A 118
ALA A 132
THR A 130
ALA A  94
 None
 1.01A 6ma6A-1xhdA:
undetectable		 6ma6A-1xhdA:
20.36