SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xhe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1xhe AEROBIC RESPIRATION
CONTROL PROTEIN ARCA
(Escherichia
coli) 		3 / 3 THR A  18
LEU A  19
LEU A  50
 None
 0.57A 1mz9C-1xheA:
undetectable		 1mz9C-1xheA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1xhe AEROBIC RESPIRATION
CONTROL PROTEIN ARCA
(Escherichia
coli) 		4 / 5 ALA A 114
PHE A  23
ILE A 101
ASP A  99
 None
 1.17A 1yc2D-1xheA:
5.4		 1yc2D-1xheA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 1xhe AEROBIC RESPIRATION
CONTROL PROTEIN ARCA
(Escherichia
coli) 		4 / 8 PHE A  23
ALA A 114
ARG A 113
LEU A  50
 None
 1.12A 2bxkA-1xheA:
undetectable		 2bxkA-1xheA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 1xhe AEROBIC RESPIRATION
CONTROL PROTEIN ARCA
(Escherichia
coli) 		3 / 3 PRO A   4
PHE A  23
ALA A 114
 None
 0.67A 3itaD-1xheA:
undetectable		 3itaD-1xheA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 1xhe AEROBIC RESPIRATION
CONTROL PROTEIN ARCA
(Escherichia
coli) 		3 / 3 LEU A  43
HIS A  40
MET A  39
 None
 0.95A 3thrD-1xheA:
3.0		 3thrD-1xheA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 1xhe AEROBIC RESPIRATION
CONTROL PROTEIN ARCA
(Escherichia
coli) 		5 / 12 ILE A 101
LEU A 117
LEU A 118
LEU A  80
MET A  78
 None
 1.02A 5nfjA-1xheA:
undetectable		 5nfjA-1xheA:
22.60