SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xhl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_A_FFOA1002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	GLY A 19 SER A 21 ALA A 22 SER A 189 PRO A 190	None None None None NDP A1278 (-4.1A)	1.13A	1dfoA-1xhlA: 3.0	1dfoA-1xhlA: 19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_B_FFOB2002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	GLY A 19 SER A 21 ALA A 22 SER A 189 PRO A 190	None None None None NDP A1278 (-4.1A)	1.12A	1dfoB-1xhlA: 3.0	1dfoB-1xhlA: 19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_C_FFOC3002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	GLY A 19 SER A 21 ALA A 22 SER A 189 PRO A 190	None None None None NDP A1278 (-4.1A)	1.13A	1dfoC-1xhlA: 2.8	1dfoC-1xhlA: 19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_D_FFOD4002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	GLY A 19 SER A 21 ALA A 22 SER A 189 PRO A 190	None None None None NDP A1278 (-4.1A)	1.12A	1dfoD-1xhlA: 2.8	1dfoD-1xhlA: 19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DVX_B_DIFB125_2 (TRANSTHYRETIN)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	4 / 7	LEU A 90 SER A 8 THR A 34 VAL A 63	None	0.99A	1dvxB-1xhlA: undetectable	1dvxB-1xhlA: 19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	GLY A 19 SER A 21 ALA A 22 SER A 189 PRO A 190	None None None None NDP A1278 (-4.1A)	1.13A	1eqbA-1xhlA: 2.9	1eqbA-1xhlA: 19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_B_FFOB2293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	GLY A 19 SER A 21 ALA A 22 SER A 189 PRO A 190	None None None None NDP A1278 (-4.1A)	1.12A	1eqbB-1xhlA: 3.0	1eqbB-1xhlA: 19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	GLY A 19 SER A 21 ALA A 22 SER A 189 PRO A 190	None None None None NDP A1278 (-4.1A)	1.13A	1eqbC-1xhlA: 3.0	1eqbC-1xhlA: 19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_D_FFOD4293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	GLY A 19 SER A 21 ALA A 22 SER A 189 PRO A 190	None None None None NDP A1278 (-4.1A)	1.13A	1eqbD-1xhlA: 2.9	1eqbD-1xhlA: 19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_C_TRPC81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	THR A 46 ALA A 23 GLY A 17 ALA A 22 ILE A 18	None None NDP A1278 (-3.1A) None NDP A1278 (-4.0A)	1.11A	1gtnB-1xhlA: undetectable 1gtnC-1xhlA: undetectable	1gtnB-1xhlA: 16.80 1gtnC-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_I_TRPI81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	THR A 46 ALA A 23 GLY A 17 ALA A 22 ILE A 18	None None NDP A1278 (-3.1A) None NDP A1278 (-4.0A)	1.11A	1gtnH-1xhlA: undetectable 1gtnI-1xhlA: undetectable	1gtnH-1xhlA: 16.80 1gtnI-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_M_TRPM81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 11	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.04A	1gtnM-1xhlA: undetectable 1gtnN-1xhlA: undetectable	1gtnM-1xhlA: 16.80 1gtnN-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_U_TRPU81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.08A	1gtnU-1xhlA: undetectable 1gtnV-1xhlA: undetectable	1gtnU-1xhlA: 16.80 1gtnV-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICT_D_T44D129_2 (TRANSTHYRETIN)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	4 / 7	LEU A 90 THR A 36 SER A 8 VAL A 63	None	0.72A	1ictD-1xhlA: undetectable	1ictD-1xhlA: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TYR_B_9CRB130_1 (TRANSTHYRETIN)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	4 / 7	LEU A 90 THR A 36 SER A 8 VAL A 63	None	0.63A	1tyrB-1xhlA: undetectable	1tyrB-1xhlA: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_T_TRPT81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.03A	1utdT-1xhlA: undetectable 1utdU-1xhlA: undetectable	1utdT-1xhlA: 16.80 1utdU-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AXN_A_EDTA737_0 (6-PHOSPHOFRUCTO-2-KI NASE/FRUCTOSE-2,6-BI PHOSPHATASE 3 (6PF-2-K/FRU- 2,6-P2ASE BRAIN/PLACENTA-TYPE ISOZYME) (IPFK-2) [INCLUDES: 6- PHOSPHOFRUCTO-2-KINA SE (EC 2.7.1.105) FRUCTOSE-2,6-BISPHO SPHATASE (EC 3.1.3.46)])	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	THR A 115 ASN A 119 GLY A 95 ALA A 122 ARG A 38	None None NDP A1278 (-3.3A) None NDP A1278 (-3.6A)	1.40A	2axnA-1xhlA: 2.2	2axnA-1xhlA: 21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AXN_A_EDTA737_0 (6-PHOSPHOFRUCTO-2-KI NASE/FRUCTOSE-2,6-BI PHOSPHATASE 3 (6PF-2-K/FRU- 2,6-P2ASE BRAIN/PLACENTA-TYPE ISOZYME) (IPFK-2) [INCLUDES: 6- PHOSPHOFRUCTO-2-KINA SE (EC 2.7.1.105) FRUCTOSE-2,6-BISPHO SPHATASE (EC 3.1.3.46)])	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	THR A 115 ASN A 119 GLY A 95 ALA A 122 THR A 68	None None NDP A1278 (-3.3A) None NDP A1278 ( 3.9A)	1.39A	2axnA-1xhlA: 2.2	2axnA-1xhlA: 21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B25_B_SAMB602_1 (HYPOTHETICAL PROTEIN)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	3 / 3	GLY A 72 GLU A 69 ASP A 75	None	0.68A	2b25B-1xhlA: 6.1	2b25B-1xhlA: 21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_A_SAMA301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	GLY A 13 ARG A 38 ARG A 42 ASP A 66 ALA A 94	NDP A1278 (-3.1A) NDP A1278 (-3.6A) NDP A1278 (-2.8A) NDP A1278 (-3.4A) NDP A1278 (-3.9A)	0.88A	2bm9A-1xhlA: 2.5	2bm9A-1xhlA: 19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_B_SAMB301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	GLY A 13 ARG A 38 ARG A 42 ASP A 66 ASN A 93	NDP A1278 (-3.1A) NDP A1278 (-3.6A) NDP A1278 (-2.8A) NDP A1278 (-3.4A) NDP A1278 (-3.9A)	1.02A	2bm9B-1xhlA: 5.2	2bm9B-1xhlA: 19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_E_SAME301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	GLY A 13 ARG A 38 ASP A 66 ASN A 93 ALA A 94	NDP A1278 (-3.1A) NDP A1278 (-3.6A) NDP A1278 (-3.4A) NDP A1278 (-3.9A) NDP A1278 (-3.9A)	0.99A	2bm9E-1xhlA: 5.3	2bm9E-1xhlA: 19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_C_SAMC301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	GLY A 13 ARG A 38 ARG A 42 ASP A 66 ALA A 94	NDP A1278 (-3.1A) NDP A1278 (-3.6A) NDP A1278 (-2.8A) NDP A1278 (-3.4A) NDP A1278 (-3.9A)	0.89A	2br4C-1xhlA: 5.3	2br4C-1xhlA: 18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DM6_A_IMNA1401_1 (NADP-DEPENDENT LEUKOTRIENE B4 12-HYDROXYDEHYDROGEN ASE)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	ILE A 25 ILE A 236 PRO A 230 GLU A 231 ILE A 233	None	1.31A	2dm6A-1xhlA: 7.7 2dm6B-1xhlA: 7.8	2dm6A-1xhlA: 21.78 2dm6B-1xhlA: 21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNI_A_MTKA501_2 (CYTOCHROME P450 2C8)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 8	ILE A 35 ILE A 11 ILE A 60 VAL A 91 ALA A 241	None	1.47A	2nniA-1xhlA: undetectable	2nniA-1xhlA: 22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q83_A_ADNA1_1 (YTAA PROTEIN)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	4 / 7	ILE A 135 ILE A 77 LEU A 81 ILE A 87	None	0.86A	2q83A-1xhlA: undetectable	2q83A-1xhlA: 21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WD9_C_IBPC1570_1 (ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	ILE A 141 LEU A 178 GLY A 182 GLY A 139 ARG A 184	None	1.23A	2wd9C-1xhlA: 4.1	2wd9C-1xhlA: 22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DL9_A_V2HA602_0 (CYTOCHROME P450 2R1)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	THR A 115 ALA A 200 VAL A 67 VAL A 193 THR A 195	None NDP A1278 ( 4.5A) NDP A1278 (-3.9A) NDP A1278 (-3.8A) NDP A1278 (-2.8A)	1.21A	3dl9A-1xhlA: undetectable	3dl9A-1xhlA: 22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DL9_B_V2HB602_0 (CYTOCHROME P450 2R1)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	VAL A 123 ALA A 122 ALA A 163 MET A 126 THR A 127	None	1.27A	3dl9B-1xhlA: undetectable	3dl9B-1xhlA: 22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IK7_B_IMNB201_1 (TRANSTHYRETIN)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	4 / 8	LEU A 90 THR A 36 SER A 8 VAL A 63	None	0.74A	4ik7B-1xhlA: undetectable	4ik7B-1xhlA: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MMF_B_29QB603_1 (TRANSPORTER)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 9	ASP A 168 VAL A 255 ALA A 256 GLY A 150 SER A 145	None	1.33A	4mmfB-1xhlA: undetectable	4mmfB-1xhlA: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RET_A_DGXA1107_2 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	4 / 4	ASN A 92 VAL A 67 THR A 130 ILE A 77	None NDP A1278 (-3.9A) None None	1.23A	4retA-1xhlA: undetectable	4retA-1xhlA: 16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RET_C_DGXC2005_2 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	4 / 4	ASN A 92 VAL A 67 THR A 130 ILE A 77	None NDP A1278 (-3.9A) None None	1.23A	4retC-1xhlA: undetectable	4retC-1xhlA: 16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XT7_A_TOPA302_1 (RV2671)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 11	ILE A 222 THR A 261 SER A 260 GLY A 259 GLU A 220	None	1.48A	4xt7A-1xhlA: 1.8	4xt7A-1xhlA: 21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y03_B_SALB801_1 (PROTEIN POLYBROMO-1)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	4 / 5	LEU A 211 TYR A 212 ALA A 192 ILE A 222	None None TNE A1279 (-4.0A) None	1.15A	4y03B-1xhlA: undetectable	4y03B-1xhlA: 18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE2_A_1YNA602_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	4 / 5	ALA A 161 TYR A 160 PRO A 190 PHE A 197	None NDP A1278 (-4.9A) NDP A1278 (-4.1A) NDP A1278 (-4.2A)	1.37A	4ze2A-1xhlA: undetectable	4ze2A-1xhlA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEU_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.03A	5eeuO-1xhlA: undetectable 5eeuP-1xhlA: undetectable	5eeuO-1xhlA: 16.80 5eeuP-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEU_R_TRPR101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.05A	5eeuQ-1xhlA: undetectable 5eeuR-1xhlA: undetectable	5eeuQ-1xhlA: 16.80 5eeuR-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.02A	5eevO-1xhlA: undetectable 5eevP-1xhlA: undetectable	5eevO-1xhlA: 16.80 5eevP-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_R_TRPR101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.04A	5eevQ-1xhlA: undetectable 5eevR-1xhlA: undetectable	5eevQ-1xhlA: 16.80 5eevR-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.02A	5eewO-1xhlA: undetectable 5eewP-1xhlA: undetectable	5eewO-1xhlA: 16.80 5eewP-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_R_TRPR101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.04A	5eewQ-1xhlA: undetectable 5eewR-1xhlA: undetectable	5eewQ-1xhlA: 16.80 5eewR-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEX_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.02A	5eexO-1xhlA: undetectable 5eexP-1xhlA: undetectable	5eexO-1xhlA: 16.80 5eexP-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEY_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.02A	5eeyO-1xhlA: undetectable 5eeyP-1xhlA: undetectable	5eeyO-1xhlA: 16.80 5eeyP-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEZ_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.02A	5eezO-1xhlA: undetectable 5eezP-1xhlA: undetectable	5eezO-1xhlA: 16.80 5eezP-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF0_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.03A	5ef0O-1xhlA: undetectable 5ef0P-1xhlA: undetectable	5ef0O-1xhlA: 16.80 5ef0P-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF1_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.03A	5ef1O-1xhlA: undetectable 5ef1P-1xhlA: undetectable	5ef1O-1xhlA: 16.80 5ef1P-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF2_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.03A	5ef2O-1xhlA: undetectable 5ef2P-1xhlA: undetectable	5ef2O-1xhlA: 16.80 5ef2P-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF3_P_TRPP101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 10	GLY A 17 ALA A 22 ILE A 18 THR A 46 ALA A 23	NDP A1278 (-3.1A) None NDP A1278 (-4.0A) None None	1.03A	5ef3O-1xhlA: undetectable 5ef3P-1xhlA: undetectable	5ef3O-1xhlA: 16.80 5ef3P-1xhlA: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_ACTA405_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	3 / 3	GLN A 107 THR A 102 ASP A 100	None	0.72A	5k9dA-1xhlA: undetectable	5k9dA-1xhlA: 24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVS_A_ADNA401_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	4 / 7	GLY A 37 ALA A 62 ASP A 75 ASN A 39	NDP A1278 (-3.8A) None None None	0.89A	5mvsA-1xhlA: 4.7	5mvsA-1xhlA: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVS_B_ADNB401_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	4 / 8	GLY A 37 ALA A 62 ASP A 75 ASN A 39	NDP A1278 (-3.8A) None None None	0.94A	5mvsB-1xhlA: 4.7	5mvsB-1xhlA: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_B_CVIB301_0 (REGULATORY PROTEIN TETR)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	5 / 12	ALA A 23 SER A 21 GLU A 231 ILE A 233 VAL A 238	None	1.21A	5vlmB-1xhlA: undetectable	5vlmB-1xhlA: 19.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DFO_A_FFOA1002_0","SERINE HYDROXYMETHYLTRANSFERASE","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  19;SER A  21;ALA A  22;SER A 189;PRO A 190","None;None;None;None;NDP A1278 (-4.1A)","1.13A","1dfoA-1xhlA:3.0","1dfoA-1xhlA:19.52"],["1DFO_B_FFOB2002_1","SERINE HYDROXYMETHYLTRANSFERASE","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  19;SER A  21;ALA A  22;SER A 189;PRO A 190","None;None;None;None;NDP A1278 (-4.1A)","1.12A","1dfoB-1xhlA:3.0","1dfoB-1xhlA:19.52"],["1DFO_C_FFOC3002_1","SERINE HYDROXYMETHYLTRANSFERASE","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  19;SER A  21;ALA A  22;SER A 189;PRO A 190","None;None;None;None;NDP A1278 (-4.1A)","1.13A","1dfoC-1xhlA:2.8","1dfoC-1xhlA:19.52"],["1DFO_D_FFOD4002_1","SERINE HYDROXYMETHYLTRANSFERASE","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  19;SER A  21;ALA A  22;SER A 189;PRO A 190","None;None;None;None;NDP A1278 (-4.1A)","1.12A","1dfoD-1xhlA:2.8","1dfoD-1xhlA:19.52"],["1DVX_B_DIFB125_2","TRANSTHYRETIN","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",4,"LEU A  90;SER A   8;THR A  34;VAL A  63","None","0.99A","1dvxB-1xhlA:undetectable","1dvxB-1xhlA:19.26"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  19;SER A  21;ALA A  22;SER A 189;PRO A 190","None;None;None;None;NDP A1278 (-4.1A)","1.13A","1eqbA-1xhlA:2.9","1eqbA-1xhlA:19.52"],["1EQB_B_FFOB2293_1","SERINE HYDROXYMETHYLTRANSFERASE","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  19;SER A  21;ALA A  22;SER A 189;PRO A 190","None;None;None;None;NDP A1278 (-4.1A)","1.12A","1eqbB-1xhlA:3.0","1eqbB-1xhlA:19.52"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  19;SER A  21;ALA A  22;SER A 189;PRO A 190","None;None;None;None;NDP A1278 (-4.1A)","1.13A","1eqbC-1xhlA:3.0","1eqbC-1xhlA:19.52"],["1EQB_D_FFOD4293_1","SERINE HYDROXYMETHYLTRANSFERASE","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  19;SER A  21;ALA A  22;SER A 189;PRO A 190","None;None;None;None;NDP A1278 (-4.1A)","1.13A","1eqbD-1xhlA:2.9","1eqbD-1xhlA:19.52"],["1GTN_C_TRPC81_0","TRP RNA-BINDING ATTENUATION PROTEIN","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"THR A  46;ALA A  23;GLY A  17;ALA A  22;ILE A  18","None;None;NDP A1278 (-3.1A);None;NDP A1278 (-4.0A)","1.11A","1gtnB-1xhlA:undetectable;1gtnC-1xhlA:undetectable","1gtnB-1xhlA:16.80;1gtnC-1xhlA:16.80"],["1GTN_I_TRPI81_0","TRP RNA-BINDING ATTENUATION PROTEIN","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"THR A  46;ALA A  23;GLY A  17;ALA A  22;ILE A  18","None;None;NDP A1278 (-3.1A);None;NDP A1278 (-4.0A)","1.11A","1gtnH-1xhlA:undetectable;1gtnI-1xhlA:undetectable","1gtnH-1xhlA:16.80;1gtnI-1xhlA:16.80"],["1GTN_M_TRPM81_0","TRP RNA-BINDING ATTENUATION PROTEIN","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.04A","1gtnM-1xhlA:undetectable;1gtnN-1xhlA:undetectable","1gtnM-1xhlA:16.80;1gtnN-1xhlA:16.80"],["1GTN_U_TRPU81_0","TRP RNA-BINDING ATTENUATION PROTEIN","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.08A","1gtnU-1xhlA:undetectable;1gtnV-1xhlA:undetectable","1gtnU-1xhlA:16.80;1gtnV-1xhlA:16.80"],["1ICT_D_T44D129_2","TRANSTHYRETIN","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",4,"LEU A  90;THR A  36;SER A   8;VAL A  63","None","0.72A","1ictD-1xhlA:undetectable","1ictD-1xhlA:19.24"],["1TYR_B_9CRB130_1","TRANSTHYRETIN","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",4,"LEU A  90;THR A  36;SER A   8;VAL A  63","None","0.63A","1tyrB-1xhlA:undetectable","1tyrB-1xhlA:19.24"],["1UTD_T_TRPT81_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.03A","1utdT-1xhlA:undetectable;1utdU-1xhlA:undetectable","1utdT-1xhlA:16.80;1utdU-1xhlA:16.80"],["2AXN_A_EDTA737_0","6-PHOSPHOFRUCTO-2-KINASE\/FRUCTOSE-2,6-BIPHOSPHATASE 3 (6PF-2-K\/FRU- 2,6-P2ASE BRAIN\/PLACENTA-TYPE ISOZYME) (IPFK-2) [INCLUDES: 6- PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105); FRUCTOSE-2,6-BISPHOSPHATASE (EC 3.1.3.46)]","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"THR A 115;ASN A 119;GLY A  95;ALA A 122;ARG A  38","None;None;NDP A1278 (-3.3A);None;NDP A1278 (-3.6A)","1.40A","2axnA-1xhlA:2.2","2axnA-1xhlA:21.86"],["2AXN_A_EDTA737_0","6-PHOSPHOFRUCTO-2-KINASE\/FRUCTOSE-2,6-BIPHOSPHATASE 3 (6PF-2-K\/FRU- 2,6-P2ASE BRAIN\/PLACENTA-TYPE ISOZYME) (IPFK-2) [INCLUDES: 6- PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105); FRUCTOSE-2,6-BISPHOSPHATASE (EC 3.1.3.46)]","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"THR A 115;ASN A 119;GLY A  95;ALA A 122;THR A  68","None;None;NDP A1278 (-3.3A);None;NDP A1278 ( 3.9A)","1.39A","2axnA-1xhlA:2.2","2axnA-1xhlA:21.86"],["2B25_B_SAMB602_1","HYPOTHETICAL PROTEIN","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",3,"GLY A  72;GLU A  69;ASP A  75","None","0.68A","2b25B-1xhlA:6.1","2b25B-1xhlA:21.91"],["2BM9_A_SAMA301_0","CEPHALOSPORIN HYDROXYLASE CMCI","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  13;ARG A  38;ARG A  42;ASP A  66;ALA A  94","NDP A1278 (-3.1A);NDP A1278 (-3.6A);NDP A1278 (-2.8A);NDP A1278 (-3.4A);NDP A1278 (-3.9A)","0.88A","2bm9A-1xhlA:2.5","2bm9A-1xhlA:19.00"],["2BM9_B_SAMB301_0","CEPHALOSPORIN HYDROXYLASE CMCI","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  13;ARG A  38;ARG A  42;ASP A  66;ASN A  93","NDP A1278 (-3.1A);NDP A1278 (-3.6A);NDP A1278 (-2.8A);NDP A1278 (-3.4A);NDP A1278 (-3.9A)","1.02A","2bm9B-1xhlA:5.2","2bm9B-1xhlA:19.00"],["2BM9_E_SAME301_0","CEPHALOSPORIN HYDROXYLASE CMCI","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  13;ARG A  38;ASP A  66;ASN A  93;ALA A  94","NDP A1278 (-3.1A);NDP A1278 (-3.6A);NDP A1278 (-3.4A);NDP A1278 (-3.9A);NDP A1278 (-3.9A)","0.99A","2bm9E-1xhlA:5.3","2bm9E-1xhlA:19.00"],["2BR4_C_SAMC301_0","CEPHALOSPORIN HYDROXYLASE CMCI","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  13;ARG A  38;ARG A  42;ASP A  66;ALA A  94","NDP A1278 (-3.1A);NDP A1278 (-3.6A);NDP A1278 (-2.8A);NDP A1278 (-3.4A);NDP A1278 (-3.9A)","0.89A","2br4C-1xhlA:5.3","2br4C-1xhlA:18.69"],["2DM6_A_IMNA1401_1","NADP-DEPENDENT LEUKOTRIENE B4 12-HYDROXYDEHYDROGENASE;NADP-DEPENDENT LEUKOTRIENE B4 12-HYDROXYDEHYDROGENASE","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"ILE A  25;ILE A 236;PRO A 230;GLU A 231;ILE A 233","None","1.31A","2dm6A-1xhlA:7.7;2dm6B-1xhlA:7.8","2dm6A-1xhlA:21.78;2dm6B-1xhlA:21.78"],["2NNI_A_MTKA501_2","CYTOCHROME P450 2C8","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"ILE A  35;ILE A  11;ILE A  60;VAL A  91;ALA A 241","None","1.47A","2nniA-1xhlA:undetectable","2nniA-1xhlA:22.66"],["2Q83_A_ADNA1_1","YTAA PROTEIN","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",4,"ILE A 135;ILE A  77;LEU A  81;ILE A  87","None","0.86A","2q83A-1xhlA:undetectable","2q83A-1xhlA:21.45"],["2WD9_C_IBPC1570_1","ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"ILE A 141;LEU A 178;GLY A 182;GLY A 139;ARG A 184","None","1.23A","2wd9C-1xhlA:4.1","2wd9C-1xhlA:22.12"],["3DL9_A_V2HA602_0","CYTOCHROME P450 2R1","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"THR A 115;ALA A 200;VAL A  67;VAL A 193;THR A 195","None;NDP A1278 ( 4.5A);NDP A1278 (-3.9A);NDP A1278 (-3.8A);NDP A1278 (-2.8A)","1.21A","3dl9A-1xhlA:undetectable","3dl9A-1xhlA:22.20"],["3DL9_B_V2HB602_0","CYTOCHROME P450 2R1","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"VAL A 123;ALA A 122;ALA A 163;MET A 126;THR A 127","None","1.27A","3dl9B-1xhlA:undetectable","3dl9B-1xhlA:22.20"],["4IK7_B_IMNB201_1","TRANSTHYRETIN","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",4,"LEU A  90;THR A  36;SER A   8;VAL A  63","None","0.74A","4ik7B-1xhlA:undetectable","4ik7B-1xhlA:19.24"],["4MMF_B_29QB603_1","TRANSPORTER","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"ASP A 168;VAL A 255;ALA A 256;GLY A 150;SER A 145","None","1.33A","4mmfB-1xhlA:undetectable","4mmfB-1xhlA:20.04"],["4RET_A_DGXA1107_2","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",4,"ASN A  92;VAL A  67;THR A 130;ILE A  77","None;NDP A1278 (-3.9A);None;None","1.23A","4retA-1xhlA:undetectable","4retA-1xhlA:16.48"],["4RET_C_DGXC2005_2","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",4,"ASN A  92;VAL A  67;THR A 130;ILE A  77","None;NDP A1278 (-3.9A);None;None","1.23A","4retC-1xhlA:undetectable","4retC-1xhlA:16.48"],["4XT7_A_TOPA302_1","RV2671","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"ILE A 222;THR A 261;SER A 260;GLY A 259;GLU A 220","None","1.48A","4xt7A-1xhlA:1.8","4xt7A-1xhlA:21.63"],["4Y03_B_SALB801_1","PROTEIN POLYBROMO-1","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",4,"LEU A 211;TYR A 212;ALA A 192;ILE A 222","None;None;TNE A1279 (-4.0A);None","1.15A","4y03B-1xhlA:undetectable","4y03B-1xhlA:18.35"],["4ZE2_A_1YNA602_2","LANOSTEROL 14-ALPHA DEMETHYLASE","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",4,"ALA A 161;TYR A 160;PRO A 190;PHE A 197","None;NDP A1278 (-4.9A);NDP A1278 (-4.1A);NDP A1278 (-4.2A)","1.37A","4ze2A-1xhlA:undetectable","4ze2A-1xhlA:18.80"],["5EEU_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.03A","5eeuO-1xhlA:undetectable;5eeuP-1xhlA:undetectable","5eeuO-1xhlA:16.80;5eeuP-1xhlA:16.80"],["5EEU_R_TRPR101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.05A","5eeuQ-1xhlA:undetectable;5eeuR-1xhlA:undetectable","5eeuQ-1xhlA:16.80;5eeuR-1xhlA:16.80"],["5EEV_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.02A","5eevO-1xhlA:undetectable;5eevP-1xhlA:undetectable","5eevO-1xhlA:16.80;5eevP-1xhlA:16.80"],["5EEV_R_TRPR101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.04A","5eevQ-1xhlA:undetectable;5eevR-1xhlA:undetectable","5eevQ-1xhlA:16.80;5eevR-1xhlA:16.80"],["5EEW_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.02A","5eewO-1xhlA:undetectable;5eewP-1xhlA:undetectable","5eewO-1xhlA:16.80;5eewP-1xhlA:16.80"],["5EEW_R_TRPR101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.04A","5eewQ-1xhlA:undetectable;5eewR-1xhlA:undetectable","5eewQ-1xhlA:16.80;5eewR-1xhlA:16.80"],["5EEX_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.02A","5eexO-1xhlA:undetectable;5eexP-1xhlA:undetectable","5eexO-1xhlA:16.80;5eexP-1xhlA:16.80"],["5EEY_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.02A","5eeyO-1xhlA:undetectable;5eeyP-1xhlA:undetectable","5eeyO-1xhlA:16.80;5eeyP-1xhlA:16.80"],["5EEZ_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.02A","5eezO-1xhlA:undetectable;5eezP-1xhlA:undetectable","5eezO-1xhlA:16.80;5eezP-1xhlA:16.80"],["5EF0_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.03A","5ef0O-1xhlA:undetectable;5ef0P-1xhlA:undetectable","5ef0O-1xhlA:16.80;5ef0P-1xhlA:16.80"],["5EF1_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.03A","5ef1O-1xhlA:undetectable;5ef1P-1xhlA:undetectable","5ef1O-1xhlA:16.80;5ef1P-1xhlA:16.80"],["5EF2_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.03A","5ef2O-1xhlA:undetectable;5ef2P-1xhlA:undetectable","5ef2O-1xhlA:16.80;5ef2P-1xhlA:16.80"],["5EF3_P_TRPP101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"GLY A  17;ALA A  22;ILE A  18;THR A  46;ALA A  23","NDP A1278 (-3.1A);None;NDP A1278 (-4.0A);None;None","1.03A","5ef3O-1xhlA:undetectable;5ef3P-1xhlA:undetectable","5ef3O-1xhlA:16.80;5ef3P-1xhlA:16.80"],["5K9D_A_ACTA405_0","DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",3,"GLN A 107;THR A 102;ASP A 100","None","0.72A","5k9dA-1xhlA:undetectable","5k9dA-1xhlA:24.82"],["5MVS_A_ADNA401_1","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",4,"GLY A  37;ALA A  62;ASP A  75;ASN A  39","NDP A1278 (-3.8A);None;None;None","0.89A","5mvsA-1xhlA:4.7","5mvsA-1xhlA:20.35"],["5MVS_B_ADNB401_1","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",4,"GLY A  37;ALA A  62;ASP A  75;ASN A  39","NDP A1278 (-3.8A);None;None;None","0.94A","5mvsB-1xhlA:4.7","5mvsB-1xhlA:20.35"],["5VLM_B_CVIB301_0","REGULATORY PROTEIN TETR","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",5,"ALA A  23;SER A  21;GLU A 231;ILE A 233;VAL A 238","None","1.21A","5vlmB-1xhlA:undetectable","5vlmB-1xhlA:19.80"]]