SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xhs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NCW_H_BEZH601_0
(IMMUNOGLOBULIN IGG2A)		 1xhs HYPOTHETICAL UPF0131
PROTEIN YTFP
(Escherichia
coli) 		5 / 9 ALA A  44
LEU A  35
GLY A 106
TRP A 108
GLY A  53
 None
 1.16A 1ncwH-1xhsA:
undetectable
1ncwL-1xhsA:
undetectable		 1ncwH-1xhsA:
19.82
1ncwL-1xhsA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1xhs HYPOTHETICAL UPF0131
PROTEIN YTFP
(Escherichia
coli) 		5 / 9 ALA A  44
LEU A  35
GLY A 106
TRP A 108
GLY A  53
 None
 1.16A 1ru9H-1xhsA:
0.0
1ru9L-1xhsA:
0.0		 1ru9H-1xhsA:
19.82
1ru9L-1xhsA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1xhs HYPOTHETICAL UPF0131
PROTEIN YTFP
(Escherichia
coli) 		5 / 10 ALA A  44
LEU A  35
GLY A 106
TRP A 108
GLY A  53
 None
 1.13A 1ruaH-1xhsA:
undetectable
1ruaL-1xhsA:
undetectable		 1ruaH-1xhsA:
19.82
1ruaL-1xhsA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1xhs HYPOTHETICAL UPF0131
PROTEIN YTFP
(Escherichia
coli) 		5 / 8 ALA A  44
LEU A  35
GLY A 106
TRP A 108
GLY A  53
 None
 1.18A 1rukH-1xhsA:
undetectable
1rukL-1xhsA:
undetectable		 1rukH-1xhsA:
19.82
1rukL-1xhsA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1xhs HYPOTHETICAL UPF0131
PROTEIN YTFP
(Escherichia
coli) 		5 / 9 ALA A  44
LEU A  35
GLY A 106
TRP A 108
GLY A  53
 None
 1.15A 1rulH-1xhsA:
0.0
1rulL-1xhsA:
undetectable		 1rulH-1xhsA:
19.82
1rulL-1xhsA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUM_H_BEZH1601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1xhs HYPOTHETICAL UPF0131
PROTEIN YTFP
(Escherichia
coli) 		5 / 9 ALA A  44
LEU A  35
GLY A 106
TRP A 108
GLY A  53
 None
 1.16A 1rumH-1xhsA:
undetectable
1rumL-1xhsA:
undetectable		 1rumH-1xhsA:
19.82
1rumL-1xhsA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUP_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1xhs HYPOTHETICAL UPF0131
PROTEIN YTFP
(Escherichia
coli) 		5 / 9 ALA A  44
LEU A  35
GLY A 106
TRP A 108
GLY A  53
 None
 1.15A 1rupH-1xhsA:
undetectable
1rupL-1xhsA:
undetectable		 1rupH-1xhsA:
19.82
1rupL-1xhsA:
19.91