SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xiq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UA5_A_06XA501_1 (CYTOCHROME P450 2B6)	1xiq	NUCLEOSIDE DIPHOSPHATE KINASE B (Plasmodium falciparum)	4 / 8	ILE A 129 THR A 41 LEU A 38 VAL A 70	None	0.85A	3ua5A-1xiqA: undetectable	3ua5A-1xiqA: 16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UA5_B_06XB501_1 (CYTOCHROME P450 2B6)	1xiq	NUCLEOSIDE DIPHOSPHATE KINASE B (Plasmodium falciparum)	4 / 7	ILE A 129 THR A 41 LEU A 38 VAL A 70	None	0.77A	3ua5B-1xiqA: undetectable	3ua5B-1xiqA: 16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4APJ_A_ACTA1635_0 (ANGIOTENSIN-CONVERTI NG ENZYME BRADYKININ-POTENTIAT ING PEPTIDE B)	1xiq	NUCLEOSIDE DIPHOSPHATE KINASE B (Plasmodium falciparum)	4 / 6	HIS A 115 GLU A 126 ASP A 118 SER A 122	None	1.18A	4apjA-1xiqA: undetectable 4apjP-1xiqA: undetectable	4apjA-1xiqA: 13.87 4apjP-1xiqA: 4.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_W_BEZW801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 BEZ-LEU-LEU)	1xiq	NUCLEOSIDE DIPHOSPHATE KINASE B (Plasmodium falciparum)	4 / 5	PHE A 25 ILE A 101 GLY A 84 ILE A 21	None	0.82A	5dzkB-1xiqA: undetectable 5dzkI-1xiqA: undetectable 5dzkW-1xiqA: undetectable	5dzkB-1xiqA: 19.91 5dzkI-1xiqA: 19.40 5dzkW-1xiqA: 5.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3UA5_A_06XA501_1","CYTOCHROME P450 2B6","1xiq","NUCLEOSIDE DIPHOSPHATE KINASE B","Plasmodium falciparum",4,"ILE A 129;THR A  41;LEU A  38;VAL A  70","None","0.85A","3ua5A-1xiqA:undetectable","3ua5A-1xiqA:16.14"],["3UA5_B_06XB501_1","CYTOCHROME P450 2B6","1xiq","NUCLEOSIDE DIPHOSPHATE KINASE B","Plasmodium falciparum",4,"ILE A 129;THR A  41;LEU A  38;VAL A  70","None","0.77A","3ua5B-1xiqA:undetectable","3ua5B-1xiqA:16.14"],["4APJ_A_ACTA1635_0","ANGIOTENSIN-CONVERTING ENZYME;BRADYKININ-POTENTIATING PEPTIDE B","1xiq","NUCLEOSIDE DIPHOSPHATE KINASE B","Plasmodium falciparum",4,"HIS A 115;GLU A 126;ASP A 118;SER A 122","None","1.18A","4apjA-1xiqA:undetectable;4apjP-1xiqA:undetectable","4apjA-1xiqA:13.87;4apjP-1xiqA:4.73"],["5DZK_W_BEZW801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1;ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2;BEZ-LEU-LEU","1xiq","NUCLEOSIDE DIPHOSPHATE KINASE B","Plasmodium falciparum",4,"PHE A  25;ILE A 101;GLY A  84;ILE A  21","None","0.82A","5dzkB-1xiqA:undetectable;5dzkI-1xiqA:undetectable;5dzkW-1xiqA:undetectable","5dzkB-1xiqA:19.91;5dzkI-1xiqA:19.40;5dzkW-1xiqA:5.00"]]