SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xjt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 1xjt LYSOZYME
(Escherichia
virus
P1) 		5 / 12 GLY A  39
GLY A  61
ASN A  31
THR A  30
ASN A 115
 None
 1.01A 2y7hB-1xjtA:
undetectable		 2y7hB-1xjtA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 1xjt LYSOZYME
(Escherichia
virus
P1) 		4 / 6 LEU A 182
ARG A  97
MET A 101
VAL A 157
 None
 1.19A 2ygoA-1xjtA:
undetectable		 2ygoA-1xjtA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFX_A_ACTA404_0
(THIAMINE
BIOSYNTHESIS
LIPOPROTEIN APBE)		 1xjt LYSOZYME
(Escherichia
virus
P1) 		4 / 5 LYS A 168
ARG A 171
LEU A 153
ASP A 155
 None
None
None
CIT  A 250 (-4.1A)
 1.45A 4ifxA-1xjtA:
0.0		 4ifxA-1xjtA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG1_A_ACTA504_0
(FAD:PROTEIN FMN
TRANSFERASE)		 1xjt LYSOZYME
(Escherichia
virus
P1) 		4 / 5 LYS A 168
ARG A 171
LEU A 153
ASP A 155
 None
None
None
CIT  A 250 (-4.1A)
 1.41A 4ig1A-1xjtA:
undetectable		 4ig1A-1xjtA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1xjt LYSOZYME
(Escherichia
virus
P1) 		5 / 12 ALA A 105
ASN A  31
ALA A  33
GLY A  34
LEU A  37
 None
 1.01A 4oaeA-1xjtA:
undetectable		 4oaeA-1xjtA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 1xjt LYSOZYME
(Escherichia
virus
P1) 		4 / 7 GLU A  42
THR A  57
GLY A  61
THR A  63
 None
 0.87A 4qwpB-1xjtA:
4.3		 4qwpB-1xjtA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 1xjt LYSOZYME
(Escherichia
virus
P1) 		4 / 4 PHE A 106
ASP A 103
GLY A  98
SER A 107
 None
 1.47A 4xp9C-1xjtA:
undetectable		 4xp9C-1xjtA:
13.68