SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xju'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 1xju LYSOZYME
(Escherichia
virus
P1) 		3 / 3 GLY A 166
ARG A 165
TYR A  49
 None
 0.66A 2opxA-1xjuA:
undetectable		 2opxA-1xjuA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 1xju LYSOZYME
(Escherichia
virus
P1) 		4 / 6 LEU A 182
ARG A  97
MET A 101
VAL A 157
 None
 1.07A 2ygoA-1xjuA:
undetectable		 2ygoA-1xjuA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 1xju LYSOZYME
(Escherichia
virus
P1) 		3 / 3 TYR A 124
ARG A 129
SER A 126
 None
SO4  A 606 (-2.9A)
SO4  A 602 (-3.9A)
 1.12A 4khpI-1xjuA:
undetectable
4khpJ-1xjuA:
undetectable		 4khpI-1xjuA:
20.48
4khpJ-1xjuA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1xju LYSOZYME
(Escherichia
virus
P1) 		5 / 12 ALA A 105
ASN A  31
ALA A  33
GLY A  34
LEU A  37
 None
 1.08A 4oaeA-1xjuA:
undetectable		 4oaeA-1xjuA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 1xju LYSOZYME
(Escherichia
virus
P1) 		4 / 4 PHE A 106
ASP A 103
GLY A  98
SER A 107
 None
 1.48A 4xp9C-1xjuA:
undetectable		 4xp9C-1xjuA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1xju LYSOZYME
(Escherichia
virus
P1) 		5 / 12 GLU A  36
LEU A 182
ALA A 108
SER A 111
ARG A 171
 None
 1.26A 5syeB-1xjuA:
undetectable		 5syeB-1xjuA:
16.00