SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xjv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1xjv PROTECTION OF
TELOMERES 1
(Homo
sapiens) 		5 / 8 ARG A 276
VAL A  28
VAL A  79
SER A 103
ILE A  71
 None
 1.45A 1igxA-1xjvA:
undetectable		 1igxA-1xjvA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 1xjv PROTECTION OF
TELOMERES 1
(Homo
sapiens) 		5 / 11 LEU A 239
ILE A 241
VAL A 222
LEU A 181
SER A 237
 None
 1.31A 2bxeA-1xjvA:
undetectable		 2bxeA-1xjvA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 1xjv PROTECTION OF
TELOMERES 1
(Homo
sapiens) 		5 / 12 LEU A 239
ILE A 241
VAL A 222
LEU A 181
SER A 237
 None
 1.21A 2bxeB-1xjvA:
undetectable		 2bxeB-1xjvA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1xjv PROTECTION OF
TELOMERES 1
(Homo
sapiens) 		3 / 3 ASP A  77
ARG A 240
LYS A  74
 None
 1.21A 3wipG-1xjvA:
undetectable		 3wipG-1xjvA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 1xjv PROTECTION OF
TELOMERES 1
(Homo
sapiens) 		5 / 12 ASN A 215
SER A 193
ARG A 195
ILE A 220
LEU A 168
 None
 1.47A 4k36A-1xjvA:
undetectable		 4k36A-1xjvA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1xjv PROTECTION OF
TELOMERES 1
(Homo
sapiens) 		5 / 12 ILE A  49
GLY A  27
ALA A 140
VAL A  79
ILE A  72
 None
 1.14A 4rvdA-1xjvA:
undetectable		 4rvdA-1xjvA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 1xjv PROTECTION OF
TELOMERES 1
(Homo
sapiens) 		4 / 7 LEU A 261
SER A 193
ILE A 218
VAL A 183
 None
 1.13A 4tvtA-1xjvA:
undetectable		 4tvtA-1xjvA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 1xjv PROTECTION OF
TELOMERES 1
(Homo
sapiens) 		4 / 7 ILE A  49
PHE A  81
VAL A  29
ILE A  72
 None
 0.99A 4zzbC-1xjvA:
undetectable
4zzbD-1xjvA:
undetectable		 4zzbC-1xjvA:
21.07
4zzbD-1xjvA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 1xjv PROTECTION OF
TELOMERES 1
(Homo
sapiens) 		4 / 8 VAL A 222
HIS A 226
LEU A 164
ILE A 275
 None
 0.86A 5v0vA-1xjvA:
undetectable		 5v0vA-1xjvA:
19.69