SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xkf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 1xkf HYPOTHETICAL PROTEIN
RV2626C
(Mycobacterium
tuberculosis) 		5 / 6 MET A   8
VAL A 104
LEU A  49
MET A  48
ILE A 105
 None
 1.44A 3gcsA-1xkfA:
undetectable		 3gcsA-1xkfA:
19.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1xkf HYPOTHETICAL PROTEIN
RV2626C
(Mycobacterium
tuberculosis) 		6 / 12 ILE A 113
THR A 115
ASP A 118
VAL A  12
ILE A  33
PRO A  37
 None
 0.97A 3kpbA-1xkfA:
16.7		 3kpbA-1xkfA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1xkf HYPOTHETICAL PROTEIN
RV2626C
(Mycobacterium
tuberculosis) 		6 / 12 ILE A 113
THR A 115
ASP A 118
VAL A  12
ILE A  33
PRO A  37
 None
 0.95A 3kpbC-1xkfA:
16.7		 3kpbC-1xkfA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1xkf HYPOTHETICAL PROTEIN
RV2626C
(Mycobacterium
tuberculosis) 		5 / 10 ILE A 113
THR A 115
ASP A 118
VAL A  12
ILE A  33
 None
 0.93A 3kpbD-1xkfA:
16.7		 3kpbD-1xkfA:
30.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1xkf HYPOTHETICAL PROTEIN
RV2626C
(Mycobacterium
tuberculosis) 		6 / 11 ILE A 113
THR A 115
ASP A 118
VAL A  12
ILE A  33
PRO A  37
 None
 0.94A 3kpcA-1xkfA:
16.7		 3kpcA-1xkfA:
29.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1xkf HYPOTHETICAL PROTEIN
RV2626C
(Mycobacterium
tuberculosis) 		6 / 12 ILE A 113
THR A 115
ASP A 118
VAL A  12
ILE A  33
PRO A  37
 None
 0.98A 3kpdB-1xkfA:
16.0		 3kpdB-1xkfA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 1xkf HYPOTHETICAL PROTEIN
RV2626C
(Mycobacterium
tuberculosis) 		6 / 12 ILE A 113
THR A 115
ASP A 118
VAL A  12
ILE A  33
PRO A  37
 None
 0.92A 3kpdC-1xkfA:
16.9		 3kpdC-1xkfA:
30.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ8_A_ASDA602_1
(CYTOCHROME P450 19A1)		 1xkf HYPOTHETICAL PROTEIN
RV2626C
(Mycobacterium
tuberculosis) 		5 / 10 ILE A 113
ILE A  33
ALA A  35
VAL A  99
MET A  90
 None
 1.46A 4kq8A-1xkfA:
undetectable		 4kq8A-1xkfA:
15.89