SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xkh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 ASP A 509
ASP A 323
ASP A 501
None
0.66A 1eizA-1xkhA:
undetectable
1eizA-1xkhA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 ASP A 509
ASP A 323
ASP A 501
None
0.65A 1ej0A-1xkhA:
undetectable
1ej0A-1xkhA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 7 ARG A 768
SER A 778
ASN A 780
ASP A 179
None
1.36A 1hwiC-1xkhA:
undetectable
1hwiC-1xkhA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 7 ARG A 768
SER A 778
ASN A 780
ASP A 179
None
1.36A 1hwiD-1xkhA:
undetectable
1hwiD-1xkhA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 11 ASP A 458
ARG A 157
GLY A 254
GLY A 530
GLN A 528
None
1.21A 1jr1A-1xkhA:
undetectable
1jr1A-1xkhA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 8 ASP A 458
GLY A 254
GLY A 530
GLN A 528
None
0.87A 1jr1B-1xkhA:
undetectable
1jr1B-1xkhA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 ARG A 227
ASP A 417
ASN A 401
None
0.80A 1nbhA-1xkhA:
undetectable
1nbhA-1xkhA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 ARG A 227
ASP A 417
ASN A 401
None
0.81A 1nbhD-1xkhA:
undetectable
1nbhD-1xkhA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 10 ASP A 509
TRP A 388
GLY A 361
GLY A 385
PHE A 382
None
1.30A 1w76B-1xkhA:
undetectable
1w76B-1xkhA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 PHE A 217
ARG A 245
ASN A 267
None
0.89A 1xzxX-1xkhA:
undetectable
1xzxX-1xkhA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B0Q_A_NMYA305_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 GLU A 142
ASP A 178
ARG A 292
GLU A 282
ASP A 239
None
1.42A 2b0qA-1xkhA:
0.0
2b0qA-1xkhA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 ASN A 401
LEU A 256
TYR A 532
ALA A 480
SER A 479
None
1.41A 2iyfB-1xkhA:
undetectable
2iyfB-1xkhA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 LEU A 762
TYR A 760
GLY A 738
None
0.63A 2ocuA-1xkhA:
undetectable
2ocuA-1xkhA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 ASP A 244
THR A 192
PRO A 193
None
0.58A 2pynB-1xkhA:
undetectable
2pynB-1xkhA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 ARG A 643
THR A 706
VAL A 704
None
0.60A 2q64A-1xkhA:
undetectable
2q64A-1xkhA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 ASP A 244
THR A 192
PRO A 193
None
0.53A 2q64B-1xkhA:
undetectable
2q64B-1xkhA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 ASP A 244
THR A 192
PRO A 193
None
0.58A 2qakB-1xkhA:
undetectable
2qakB-1xkhA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 6 GLY A 508
ILE A 510
ILE A 430
ASP A 507
None
0.70A 3a7eA-1xkhA:
undetectable
3a7eA-1xkhA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 7 VAL A 197
TYR A 207
ILE A 185
ASP A 187
None
1.16A 3bu1A-1xkhA:
undetectable
3bu1A-1xkhA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 ASP A 509
ASP A 323
ASP A 501
None
0.66A 3douA-1xkhA:
undetectable
3douA-1xkhA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 HIS A 324
ASN A 384
PRO A 367
SER A 440
PHE A 503
None
1.33A 3g4lA-1xkhA:
undetectable
3g4lA-1xkhA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 8 SER A 381
ARG A 380
PHE A 321
ASP A 323
None
1.28A 3n62B-1xkhA:
undetectable
3n62B-1xkhA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 GLN A 415
GLU A 403
LYS A 413
None
1.14A 3su9A-1xkhA:
undetectable
3su9A-1xkhA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 7 THR A 154
GLY A 221
ASN A 267
GLY A 258
None
0.82A 3tajA-1xkhA:
undetectable
3tajA-1xkhA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 ASP A 244
THR A 192
PRO A 193
None
0.64A 3tkgD-1xkhA:
undetectable
3tkgD-1xkhA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 ASN A 205
ASP A 186
LEU A 268
GLY A 234
SER A 232
None
1.30A 4djeA-1xkhA:
undetectable
4djeA-1xkhA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 6 THR A 154
GLY A 221
ASN A 267
GLY A 258
None
0.83A 4fjpA-1xkhA:
undetectable
4fjpA-1xkhA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 6 ASP A 803
ASP A 187
ASP A 203
ASN A 184
None
1.30A 4gkhJ-1xkhA:
undetectable
4gkhJ-1xkhA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 8 SER A 479
TYR A 532
PRO A 223
GLN A 218
None
1.21A 4j7uD-1xkhA:
undetectable
4j7uD-1xkhA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 SER A 479
PRO A 223
GLN A 218
ASP A 591
GLY A 260
None
1.48A 4j7xF-1xkhA:
undetectable
4j7xF-1xkhA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 SER A 479
TYR A 532
GLN A 218
ASP A 591
GLY A 260
None
1.26A 4j7xF-1xkhA:
undetectable
4j7xF-1xkhA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 SER A 479
TYR A 532
PRO A 223
GLN A 218
ASP A 591
None
1.11A 4j7xJ-1xkhA:
undetectable
4j7xJ-1xkhA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 5 SER A 481
ARG A 227
PRO A 223
SER A 456
None
1.38A 4k17B-1xkhA:
undetectable
4k17B-1xkhA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA408_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 6 TYR A 789
PRO A 804
ARG A 190
PHE A 321
None
1.33A 4kf9A-1xkhA:
undetectable
4kf9A-1xkhA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 11 VAL A 331
THR A 397
PHE A 217
LEU A 268
THR A 329
None
1.43A 4kyaA-1xkhA:
undetectable
4kyaA-1xkhA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 11 VAL A 331
THR A 397
PHE A 217
LEU A 268
THR A 329
None
1.43A 4kyaE-1xkhA:
undetectable
4kyaE-1xkhA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 ASP A 201
TRP A 515
SER A 232
None
SO4  A2001 (-4.7A)
None
1.08A 4lrhA-1xkhA:
undetectable
4lrhA-1xkhA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 ALA A 634
GLY A 672
ALA A 264
GLY A 251
PHE A 636
None
1.20A 4r29A-1xkhA:
undetectable
4r29A-1xkhA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 LYS A 272
ARG A 308
HIS A 275
None
1.06A 4zbrA-1xkhA:
undetectable
4zbrA-1xkhA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 7 GLY A 258
GLY A 260
SER A 261
ASP A 553
None
0.78A 5ergB-1xkhA:
undetectable
5ergB-1xkhA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 GLY A 508
ASN A 384
GLY A 511
GLY A 361
SER A 389
None
1.12A 5hikA-1xkhA:
undetectable
5hikA-1xkhA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 4 ASN A 267
ILE A 570
TYR A 532
PHE A 546
None
1.21A 5igvA-1xkhA:
0.2
5igvA-1xkhA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
3 / 3 GLY A 558
ASP A 524
ASN A 228
None
0.56A 5jglA-1xkhA:
undetectable
5jglA-1xkhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 8 TYR A 219
SER A 261
ASN A 215
SER A 454
None
1.10A 5l1fA-1xkhA:
undetectable
5l1fB-1xkhA:
undetectable
5l1fA-1xkhA:
22.64
5l1fB-1xkhA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 GLU A 674
SER A 632
THR A 156
ARG A 210
LEU A 249
None
1.35A 5m50B-1xkhA:
undetectable
5m50B-1xkhA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 GLU A 674
SER A 632
THR A 156
ARG A 210
LEU A 249
None
1.46A 5m54B-1xkhA:
undetectable
5m54B-1xkhA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 ARG A 157
GLN A 167
THR A 141
GLY A 150
THR A 151
None
1.33A 5oj0A-1xkhA:
undetectable
5oj0A-1xkhA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 6 GLY A 802
THR A 791
GLN A 757
TYR A 760
None
1.30A 6ag0A-1xkhA:
undetectable
6ag0A-1xkhA:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
4 / 6 GLY A 802
THR A 791
GLN A 757
TYR A 760
None
1.26A 6ag0C-1xkhA:
undetectable
6ag0C-1xkhA:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 VAL A 246
ASP A 178
SER A 810
SER A 778
VAL A 188
None
1.46A 6h7lA-1xkhA:
undetectable
6h7lA-1xkhA:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa)
5 / 12 VAL A 246
ASP A 178
SER A 810
SER A 778
VAL A 188
None
1.49A 6h7lB-1xkhA:
undetectable
6h7lB-1xkhA:
8.20