SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xm7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 6 VAL A 169
ILE A   5
TRP A  65
LEU A  86
 None
 1.17A 1j96A-1xm7A:
undetectable		 1j96A-1xm7A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 7 PHE A  90
ILE A 177
THR A   8
ILE A 182
 None
 0.96A 2v0mB-1xm7A:
undetectable		 2v0mB-1xm7A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 8 HIS A   9
ASP A  50
HIS A 147
ASP A   7
 None
 1.06A 2xadA-1xm7A:
undetectable		 2xadA-1xm7A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 8 HIS A   9
ASP A  50
HIS A 147
ASP A   7
 None
 1.06A 2xadB-1xm7A:
undetectable		 2xadB-1xm7A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 8 HIS A   9
ASP A  50
HIS A 147
ASP A   7
 None
 1.05A 2xadC-1xm7A:
undetectable		 2xadC-1xm7A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 8 HIS A   9
ASP A  50
HIS A 147
ASP A   7
 None
 1.06A 2xadD-1xm7A:
undetectable		 2xadD-1xm7A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 5 TYR A  94
ILE A  73
LEU A  48
LEU A 109
 None
 1.15A 2zb7A-1xm7A:
undetectable		 2zb7A-1xm7A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		3 / 3 ASP A  80
PHE A  90
SER A  85
 None
 0.95A 3i5uB-1xm7A:
undetectable		 3i5uB-1xm7A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 5 TYR A 133
ILE A 132
ASN A 137
ILE A  99
 None
 1.01A 4jtpA-1xm7A:
undetectable		 4jtpA-1xm7A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 6 VAL A 169
ILE A   5
TRP A  65
LEU A  74
 None
 0.85A 4l1wB-1xm7A:
undetectable		 4l1wB-1xm7A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		5 / 7 VAL A 169
ILE A   5
TRP A  65
LEU A  86
LEU A  74
 None
 1.36A 4xo7A-1xm7A:
undetectable		 4xo7A-1xm7A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		5 / 12 LEU A 109
ILE A 142
LEU A 140
ILE A 165
ILE A 177
 None
 0.75A 4y0rA-1xm7A:
undetectable		 4y0rA-1xm7A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		5 / 12 LEU A 109
LEU A  48
ILE A 142
LEU A 140
ILE A 177
 None
 0.96A 4y0rA-1xm7A:
undetectable		 4y0rA-1xm7A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		5 / 12 LEU A 140
ILE A 107
LEU A 109
LYS A  98
ILE A 100
 None
 0.90A 4y0rA-1xm7A:
undetectable		 4y0rA-1xm7A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 7 ILE A 107
HIS A 143
LEU A  48
ALA A 167
 None
 1.01A 5hrqE-1xm7A:
undetectable
5hrqF-1xm7A:
undetectable
5hrqJ-1xm7A:
undetectable		 5hrqE-1xm7A:
7.14
5hrqF-1xm7A:
9.58
5hrqJ-1xm7A:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		5 / 6 ASP A  50
ASP A   7
HIS A   9
HIS A 147
HIS A 111
 None
 1.09A 5ncdA-1xm7A:
undetectable
5ncdD-1xm7A:
undetectable		 5ncdA-1xm7A:
24.80
5ncdD-1xm7A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		5 / 6 ASP A  50
ASP A   7
HIS A   9
HIS A 147
HIS A 111
 None
 1.06A 5ncdB-1xm7A:
undetectable
5ncdC-1xm7A:
undetectable		 5ncdB-1xm7A:
24.80
5ncdC-1xm7A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 4 ASP A  50
HIS A   9
HIS A 147
HIS A 111
 None
 1.08A 5ncdD-1xm7A:
undetectable		 5ncdD-1xm7A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		5 / 6 ASP A  50
ASP A   7
HIS A   9
HIS A 147
HIS A 111
 None
 1.08A 5nelA-1xm7A:
undetectable
5nelD-1xm7A:
undetectable		 5nelA-1xm7A:
24.80
5nelD-1xm7A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 6 ASP A  50
HIS A   9
HIS A 147
HIS A 111
 None
 1.02A 5nelB-1xm7A:
undetectable
5nelC-1xm7A:
undetectable		 5nelB-1xm7A:
24.80
5nelC-1xm7A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 6 HIS A   9
HIS A 145
HIS A 111
HIS A 147
 None
 1.04A 5nelB-1xm7A:
undetectable
5nelC-1xm7A:
undetectable		 5nelB-1xm7A:
24.80
5nelC-1xm7A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 4 ARG A 125
TYR A 122
HIS A 145
HIS A 111
 None
 1.49A 5os7A-1xm7A:
0.0		 5os7A-1xm7A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1xm7 HYPOTHETICAL PROTEIN
AQ_1665
(Aquifex
aeolicus) 		4 / 4 ARG A 125
TYR A 122
HIS A 145
HIS A 111
 None
 1.49A 6gmdB-1xm7A:
0.0		 6gmdB-1xm7A:
19.83