SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xn6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
3 / 4 VAL A  83
TRP A 104
TRP A  76
None
1.25A 1gmkA-1xn6A:
undetectable
1gmkB-1xn6A:
undetectable
1gmkA-1xn6A:
6.12
1gmkB-1xn6A:
6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.07A 1zzrA-1xn6A:
undetectable
1zzrB-1xn6A:
undetectable
1zzrA-1xn6A:
15.40
1zzrB-1xn6A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.06A 1zzrA-1xn6A:
undetectable
1zzrB-1xn6A:
undetectable
1zzrA-1xn6A:
15.40
1zzrB-1xn6A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.06A 1zzuA-1xn6A:
undetectable
1zzuB-1xn6A:
undetectable
1zzuA-1xn6A:
15.40
1zzuB-1xn6A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.04A 1zzuA-1xn6A:
undetectable
1zzuB-1xn6A:
undetectable
1zzuA-1xn6A:
15.40
1zzuB-1xn6A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
3 / 3 PHE A  42
ASN A  40
PHE A  37
None
0.77A 2zbuD-1xn6A:
undetectable
2zbuD-1xn6A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.10A 3dqrA-1xn6A:
undetectable
3dqrB-1xn6A:
undetectable
3dqrA-1xn6A:
15.33
3dqrB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.02A 3jx2A-1xn6A:
undetectable
3jx2B-1xn6A:
undetectable
3jx2A-1xn6A:
15.33
3jx2B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.08A 3jx2A-1xn6A:
undetectable
3jx2B-1xn6A:
undetectable
3jx2A-1xn6A:
15.33
3jx2B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.05A 3jx3A-1xn6A:
undetectable
3jx3B-1xn6A:
undetectable
3jx3A-1xn6A:
15.33
3jx3B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.07A 3jx3A-1xn6A:
undetectable
3jx3B-1xn6A:
undetectable
3jx3A-1xn6A:
15.33
3jx3B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 6 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.02A 3jx4A-1xn6A:
0.0
3jx4B-1xn6A:
0.0
3jx4A-1xn6A:
15.33
3jx4B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.00A 3jx4A-1xn6A:
undetectable
3jx4B-1xn6A:
undetectable
3jx4A-1xn6A:
15.33
3jx4B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.01A 3jx5A-1xn6A:
undetectable
3jx5B-1xn6A:
undetectable
3jx5A-1xn6A:
15.33
3jx5B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.06A 3jx5A-1xn6A:
undetectable
3jx5B-1xn6A:
undetectable
3jx5A-1xn6A:
15.33
3jx5B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.07A 3jx6A-1xn6A:
undetectable
3jx6B-1xn6A:
undetectable
3jx6A-1xn6A:
15.33
3jx6B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
0.98A 3jx6A-1xn6A:
undetectable
3jx6B-1xn6A:
undetectable
3jx6A-1xn6A:
15.33
3jx6B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 6 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.07A 3n61A-1xn6A:
undetectable
3n61B-1xn6A:
undetectable
3n61A-1xn6A:
15.33
3n61B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.08A 3n61A-1xn6A:
undetectable
3n61B-1xn6A:
undetectable
3n61A-1xn6A:
15.33
3n61B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.08A 3nljA-1xn6A:
undetectable
3nljB-1xn6A:
undetectable
3nljA-1xn6A:
15.33
3nljB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.09A 3nljA-1xn6A:
undetectable
3nljB-1xn6A:
undetectable
3nljA-1xn6A:
15.33
3nljB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
0.99A 3nlpA-1xn6A:
undetectable
3nlpB-1xn6A:
undetectable
3nlpA-1xn6A:
15.33
3nlpB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.03A 3nlpA-1xn6A:
undetectable
3nlpB-1xn6A:
undetectable
3nlpA-1xn6A:
15.33
3nlpB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 8 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.03A 3nlqA-1xn6A:
undetectable
3nlqB-1xn6A:
undetectable
3nlqA-1xn6A:
15.33
3nlqB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.09A 3nlqA-1xn6A:
undetectable
3nlqB-1xn6A:
undetectable
3nlqA-1xn6A:
15.33
3nlqB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.01A 3nlrA-1xn6A:
undetectable
3nlrB-1xn6A:
undetectable
3nlrA-1xn6A:
15.33
3nlrB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 8 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.01A 3nlrA-1xn6A:
undetectable
3nlrB-1xn6A:
undetectable
3nlrA-1xn6A:
15.33
3nlrB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.07A 4cx3A-1xn6A:
undetectable
4cx3B-1xn6A:
undetectable
4cx3A-1xn6A:
15.33
4cx3B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.06A 4cx3A-1xn6A:
undetectable
4cx3B-1xn6A:
undetectable
4cx3A-1xn6A:
15.33
4cx3B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.08A 4cx4A-1xn6A:
undetectable
4cx4B-1xn6A:
undetectable
4cx4A-1xn6A:
15.33
4cx4B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.06A 4cx4A-1xn6A:
undetectable
4cx4B-1xn6A:
undetectable
4cx4A-1xn6A:
15.33
4cx4B-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 6 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.04A 5addA-1xn6A:
undetectable
5addB-1xn6A:
undetectable
5addA-1xn6A:
15.33
5addB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.05A 5addA-1xn6A:
undetectable
5addB-1xn6A:
undetectable
5addA-1xn6A:
15.33
5addB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 6 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.06A 5adeA-1xn6A:
undetectable
5adeB-1xn6A:
undetectable
5adeA-1xn6A:
15.33
5adeB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.02A 5adeA-1xn6A:
undetectable
5adeB-1xn6A:
undetectable
5adeA-1xn6A:
15.33
5adeB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 VAL A  27
VAL A 140
TRP A  36
PHE A  16
None
1.02A 5g0pA-1xn6A:
undetectable
5g0pB-1xn6A:
undetectable
5g0pA-1xn6A:
15.33
5g0pB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 7 PHE A  16
VAL A  27
VAL A 140
TRP A  36
None
1.05A 5g0pA-1xn6A:
undetectable
5g0pB-1xn6A:
undetectable
5g0pA-1xn6A:
15.33
5g0pB-1xn6A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)
1xn6 HYPOTHETICAL PROTEIN
BC4709

(Bacillus
cereus)
4 / 6 LEU A  72
SER A  73
PHE A  74
HIS A 101
None
1.08A 5om3A-1xn6A:
undetectable
5om3B-1xn6A:
undetectable
5om3A-1xn6A:
24.51
5om3B-1xn6A:
15.83