SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xnf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		3 / 3 THR A 236
LEU A 240
LEU A 247
 None
 0.63A 1mz9C-1xnfA:
undetectable		 1mz9C-1xnfA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		4 / 6 LEU A 172
THR A 107
TYR A 142
TYR A 239
 None
 1.25A 1qvuA-1xnfA:
undetectable		 1qvuA-1xnfA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_1
(ADENOSYLHOMOCYSTEINA
SE)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		5 / 12 THR A 107
ASP A 120
LEU A 148
LEU A 140
GLY A 137
 None
 1.07A 1xwfA-1xnfA:
undetectable		 1xwfA-1xnfA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_1
(ADENOSYLHOMOCYSTEINA
SE)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		5 / 12 THR A 107
ASP A 120
LEU A 148
LEU A 140
GLY A 137
 None
 1.06A 1xwfB-1xnfA:
undetectable		 1xwfB-1xnfA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_1
(ADENOSYLHOMOCYSTEINA
SE)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		5 / 12 THR A 107
ASP A 120
LEU A 148
LEU A 140
GLY A 137
 None
 1.06A 1xwfC-1xnfA:
undetectable		 1xwfC-1xnfA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_1
(ADENOSYLHOMOCYSTEINA
SE)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		5 / 12 THR A 107
ASP A 120
LEU A 148
LEU A 140
GLY A 137
 None
 1.08A 1xwfD-1xnfA:
undetectable		 1xwfD-1xnfA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		5 / 11 LEU A 154
ALA A 182
LEU A 186
SER A 167
LEU A 170
 None
 1.31A 2c12F-1xnfA:
undetectable		 2c12F-1xnfA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		5 / 9 LEU A 278
LEU A 280
LEU A 281
PHE A 257
TYR A 142
 None
 1.24A 2f78B-1xnfA:
undetectable		 2f78B-1xnfA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		5 / 9 LEU A 278
LEU A 280
LEU A 281
PHE A 257
TYR A 142
 None
 1.23A 2f7aB-1xnfA:
undetectable		 2f7aB-1xnfA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		5 / 9 ILE A 138
TYR A 141
LEU A 276
GLU A 277
LYS A 242
 None
 1.09A 3f78A-1xnfA:
undetectable		 3f78A-1xnfA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_B_ICFB2_1
(INTEGRIN ALPHA-L)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		5 / 9 ILE A 138
TYR A 141
LEU A 276
GLU A 277
LYS A 242
 None
 1.15A 3f78B-1xnfA:
undetectable		 3f78B-1xnfA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		4 / 7 ASN A 100
ALA A 132
GLY A 137
ILE A 138
 None
 0.77A 3spkB-1xnfA:
undetectable		 3spkB-1xnfA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		5 / 12 LEU A 256
LEU A 259
LEU A 219
MET A 216
ILE A 202
 None
 1.12A 4ok1A-1xnfA:
0.0		 4ok1A-1xnfA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		5 / 12 GLY A 143
GLY A 144
ALA A 149
ASN A 135
SER A 121
 None
 0.91A 4rtmA-1xnfA:
undetectable		 4rtmA-1xnfA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		4 / 8 GLY A 241
ASN A 237
SER A 234
PHE A 238
 None
 0.77A 5xu8A-1xnfA:
undetectable		 5xu8A-1xnfA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1xnf LIPOPROTEIN NLPI
(Escherichia
coli) 		5 / 12 PHE A 257
TYR A 141
PHE A 238
LEU A 245
LEU A 280
 None
 1.17A 5y2oA-1xnfA:
0.0		 5y2oA-1xnfA:
12.55